Evaluating gene x psychological risk factor effects in the pathogenesis of anxiety: a new model approach

The present study evaluated the singular and interactive effects of a functional polymorphism (variation) in the serotonin transporter (5-HTT) gene and a psychological trait (anxiety sensitivity [AS], i.e., fear of arousal symptoms) in predicting subjective and physiological responses to a 35% carbon dioxide (CO2) challenge in a community sample (N = 72). Genotypes were divided into 2 groups in accord with prior research. Findings were partially supportive of the hypothesized risk model. These indicated that the Group L genotype (homozygous for the 1 allele), compared with the Group S genotype (homozygous for the s allele plus heterozygous individuals), predicted greater fearful response to the biological challenge. There was also an AS x Genotype interaction predicting heart rate variability (HRV) in response to the CO2, suggesting that high AS plus Group L status predicts decreased HRV.     

Perceptual assumptions and projective distortions in a three-dimensional shape illusion

We examine a shape illusion, in which the balconies of a building appear to tilt up or down, depending on the viewpoint. The balconies are actually level parallelogram shapes, but appear as tilted rectangles. We measured the illusory tilts observed when parallelogram shapes are viewed above the line of sight, using three-dimensional stimuli consisting of parallelograms of various tilts viewed at different orientations. Under perspective projection, parallelism and orthogonality are not preserved. However, perspective distortions alone cannot account for the perceived tilts measured in these experiments, since observers perceived illusory tilts even for stimuli in the frontoparallel plane. We introduce a model, based on the theory that observers assume ambiguously projected three-dimensional angles to be equal to 90 degrees, but revise their predictions on the basis of observation. In the model, perceived tilt is predicted as a weighted sum of the tilts predicted by the assumptions that the shape is rectangular, and that the shape is level (i.e. that the angle between the shape and the vertical backboard is equal to 90 degrees). We prove that it is mathematically impossible for a planar rectangle to share a projection with a nonrectangular parallelogram. A less restrictive assumption that just the two leading internal angles are equal to 90 degrees is suggested as an alternative, and it is further proven that this new configuration of angles leads to a unique perceived tilt. The relative weights in the model reflect the amount that each prediction is revised, and are shown to vary systematically with stimulus orientation. For some observers a better fit was found by replacing the level-tilt assumptions with an assumption that physical tilt was equal to the projected tilt.     

Illusory illusions: the significance of fixation on the perception of geometrical illusions

Some well-known geometrical illusions disappear when the eyes are fixating and saccades are suppressed for a period of time. This disappearance is not accompanied by fading due to stabilisation of the retinal image. Any saccade made on purpose restores the illusion immediately. The fixation time after which some illusions disappeared was measured for four illusions and four subjects each. Effects of practice have been observed after measurements were repeated on successive days. Present theories of vision cannot readily explain the effect.     

Circadian phase-shifted rats show normal acquisition but impaired long-term retention of place information in the water task

It is thought that circadian rhythms may influence learning and memory processes. However, research supporting this view does not dissociate a mnemonic impairment from other performance deficits. Furthermore, published reports do not specify the type of memory system influenced by the circadian system. The present study assessed the effects of phase shifting on acquisition and expression of place navigation in the water maze, a task sensitive to hippocampal dysfunction. The results showed that phase-shifting circadian rhythms in rats impaired the expression of place information on a retention test but not initial acquisition or encoding of place information. These results suggest that disruption of circadian rhythms may impair consolidation of previously encoded hippocampal place information.     

Models of self and others and their relation to positive and negative caregiving responses

The burden of providing informal care to a family member can lead to caregiver depression and potentially harmful caregiving behavior. Given the interpersonal nature of caregiving, the relationship between caregivers and care recipients may impact caregiver responses. We applied attachment theory to understanding caregiver depression, and both potentially harmful and exemplary caregiving responses. We present data from 430 caregivers in the Family Relationships in Late Life (FRILL 2) Project, a multisite, longitudinal study of caregiving. Age, gender, and model of self were related to caregiving responses, suggesting that model of self may help identify caregivers at risk for poor responses.     

Ethical Assurance Statements in Political Science Journals

Many journals in the physical sciences require authors to submit assurances of compliance with human subjects and other research ethics standards. These requirements do not cover all disciplines equally, however. In this paper we report on the findings of a survey of perceptions of ethical and managerial problems from journal editors in political science and related disciplines. Our results show that few journals in political science require assurance statements common to journals for other scientific disciplines. We offer some reasons for this as well as some recommendations for implementing ethical assurance safeguards for political science.     

Are cross-cultural comparisons of personality profiles meaningful? Differential item and facet functioning in the Revised NEO Personality Inventory

Measurement invariance is a prerequisite for confident cross-cultural comparisons of personality profiles. Multigroup confirmatory factor analysis was used to detect differential item functioning (DIF) in factor loadings and intercepts for the Revised NEO Personality Inventory (P. T. Costa, Jr., & R. R. McCrae, 1992) in comparisons of college students in the United States (N = 261), Philippines (N = 268), and Mexico (N = 775). About 40%-50% of the items exhibited some form of DIF and item-level noninvariance often carried forward to the facet level at which scores are compared. After excluding DIF items, some facet scales were too short or unreliable for cross-cultural comparisons, and for some other facets, cultural mean differences were reduced or eliminated. The results indicate that considerable caution is warranted in cross-cultural comparisons of personality profiles.