Time-dependent effects of treadmill exercise on aversive memory and cyclooxygenase pathway function

Exercise induces brain function adaptations and improves learning and memory; however the time window of exercise effects has been poorly investigated. Studies demonstrate an important role for cyclooxygenase-2 (COX-2) pathway function in the mechanisms underlying memory formation. The aim of present work was to investigate the effects of treadmill exercise on aversive memory and COX-2, PGE(2) and E-prostanoid receptors contents in the rat hippocampus at different time points after exercise has ended. Adult male Wistar rats were assigned to non-exercised (sedentary) and exercised (running daily for 20min, for 2weeks) groups. The inhibitory avoidance task was used to assess aversive memory and the COX-2, PGE(2) and E-prostanoid receptors (EP1, EP2, EP3 and EP4) levels were determined 1h, 18h, 3days or 7days after the last training session of treadmill exercise. The step down latency in the inhibitory avoidance, COX-2 and EP4 receptors levels were acutely increased by exercise, with a significant positive correlation between aversive memory performance and COX-2 levels. Increased EP2 content decreased PGE(2) levels were observed 7days after the last running session. The treadmill exercise protocol facilitates inhibitory avoidance memory and induces time-dependent changes on COX-2 pathways function (COX-2, PGE(2) and EP receptors).     

The role of stability in the dynamics of learning, memorizing, and forgetting new coordination patterns

According to a dynamic theory of learning, how a new memory is formed depends on the stability of the nearest preexisting memories. To predict retention after practice, the authors analyzed how 15 participants memorized 2 bimanual coordination patterns (45 degrees or 135 degrees relative phase). The authors assessed (a) how participants memorized the required patterns with learning and (b) how the associated memory layout evolved. Results showed that a practiced 45 degrees pattern near a very stable memory (0 degrees ) persisted, whereas a 135 degrees pattern near a less stable memory (180 degrees ) was forgotten. Those findings corroborate the proposition that retention of coordination patterns depends on the stability of the extant motor memories. The authors discuss that proposal in terms of the coevolution of accuracy and stability with learning to predict persistence of required or false memories.     

How emotional auditory stimuli modulate time perception

Emotional and neutral sounds rated for valence and arousal were used to investigate the influence of emotions on timing in reproduction and verbal estimation tasks with durations from 2 s to 6 s. Results revealed an effect of emotion on temporal judgment, with emotional stimuli judged to be longer than neutral ones for a similar arousal level. Within scalar expectancy theory (J. Gibbon, R. Church, & W. Meck, 1984), this suggests that emotion-induced activation generates an increase in pacemaker rate, leading to a longer perceived duration. A further exploration of self-assessed emotional dimensions showed an effect of valence and arousal. Negative sounds were judged to be longer than positive ones, indicating that negative stimuli generate a greater increase of activation. High-arousing stimuli were perceived to be shorter than low-arousing ones. Consistent with attentional models of timing, this seems to reflect a decrease of attention devoted to time, leading to a shorter perceived duration. These effects, robust across the 2 tasks, are limited to short intervals and overall suggest that both activation and attentional processes modulate the timing of emotional events.     

Delineating the construct network of the Personnel Reaction Blank: associations with externalizing tendencies and normal personality

Integrity testing has long been utilized in personnel selection to screen for tendencies toward counterproductive workplace behaviors. The construct of externalizing from the psychopathology literature represents a coherent spectrum marked by disinhibitory traits and behaviors. The present study drew on a sample of male and female undergraduates to examine the construct network of the Personnel Reaction Blank (PRB; H. G. Gough, R. D. Arvey, & P. Bradley, 2004), a measure of integrity, in relation to externalizing as well as normal-range personality constructs assessed by the Multidimensional Personality Questionnaire (MPQ; A. Tellegen & N. G. Waller, 2008). Results revealed moderate to strong associations between several PRB scales and externalizing, which were largely accounted for by MPQ traits subsumed by Negative Emotionality and Constraint. After accounting for MPQ traits in the prediction of externalizing, a modest predictive increment was achieved when adding the PRB scales, particularly biographical indicators from the Prosocial Background subscale. The findings highlight externalizing as a focal criterion for scale development in the integrity testing literature and help delineate the construct network of the PRB within the domains of personality and psychopathology.     

Primal seduction, matricial space and asymmetry in the psychoanalytic encounter

Wishing to highlight the asymmetric dimension that characterizes ethics as 'responsibility toward the other' in Levinas's philosophy, the author presents as an introduction three related concepts of Levinas's thinking: the caress, the face, the saying. Following some poetic narrative reflections offered as 'interlude' moments, the author seeks to bring together her concept of 'matricial space' inspired by Levinas's conception of ethics and the Laplanchian concept of 'primal seduction', both based on asymmetry. She suggests adding to Laplanche's proposition of two kinds of transference (filled-in transference and hollowed-out transference) a third kind: the matricial-space transference. She argues that together with the hollowed-out transference, which is related to the primal seduction, the matricial-space transference, which relates to the matricial position in the parent/analyst, is provoked by the analyst. If the hollowed-out transference assures the moving-on of the analysis, the matricial-space transference, in combination with the hollowed-out transference, is prerequisite for transformation to occur and may be deciphered specifically in 'impasse' situations, at what she coined 'subjectal moments'. As a conclusion, while insisting on the need for asymmetry in the analytic encounter, she suggests the existence in the human neonate of a need for ethics, and she questions the origin of the human capacity to be responsible toward the other. She illustrates her argument using clinical material from her own work alongside that of other authors.     

Differential involvement of internal clock and working memory in the production and reproduction of duration: a study on older adults

The present study uses the inter-individual variability in time perception of a group of elderly participants to differentiate the processes underlying time production and time reproduction. Participants performed duration production and reproduction tasks. They were also administered working memory tests and a spontaneous motor tempo task. The findings suggest that duration production and duration reproduction involve different mechanisms. Correlational analyses revealed a double dissociation: production was only correlated with spontaneous motor tempo and reproduction only with working memory measures. These findings suggest that the internal clock rate modulates the production of duration and that reproduced duration varies according to working memory capacities.     

Temporal differentiation of response duration in children of different ages: developmental changes in relations between verbal and nonverbal behavior.

Children aged 4.5, 7, or 11 years received an experimental session in which a contingency was placed on button-press duration. Each discrete trial was followed by a brief verbal probe asking a question about the contingency requirement. Other groups of children received an identical task followed by a postexperimental interview. Level of adaptation to the duration contingency tended to increase with age in subjects receiving posttrial verbal probes, but not for those who were interviewed. Eleven-year-olds in the verbal probe condition showed a strong correlation between accurate temporal differentiation and number of verbalizations relating to response duration or timing. The younger subjects, with one exception, showed no association between timing-related verbalizations (which were almost totally absent) and response duration differentiation. This developmental difference occurred even though the younger subjects verbalized after almost every trial. The results suggest that although 11-year-old children apparently produce rule-governed behavior under verbal control as adults do, the behavior of younger children may be controlled directly by reinforcement contingencies even when their verbal repertoires are highly developed.     

Affect and between-meal snacking in daily life: the moderating role of gender and age

Objective: Affect-related energy intake from snacks remains relatively unexplored in daily life. This study examines the associations between momentary positive affect (PA) and momentary negative affect (NA) and subsequent energy intake from snacks. In addition, the moderating role of BMI, gender, age and level of education is investigated.

Design: Adults (N = 269), aged 20–50, participated in this study. Demographics were assessed in an online composite questionnaire. An experience sampling smartphone application was used to map momentary NA/PA and energy intake (kilocalories) from snacks in the context of daily life.

Main outcome measures: Energy intake from moment-to-moment self-reported snacks in real-life settings.

Results: A significant negative main effect of momentary NA on moment-to-moment energy intake was found. The higher the momentary NA, the lower the subsequent amount of kilocalories consumed. There was no main effect with regard to PA. Interaction analyses showed that men decreased their energy intake after experiencing NA, and increased their intake after experiencing PA. No associations were found in women. Additionally, young adults (20–30) increased their energy intake after experiencing PA. No associations were found in the other age groups.

Conclusion: Interventions aiming at reducing energy intake might also address PA-related snacking in young adults and men.