Cognitive and emotional influences in anterior cingulate cortex

Anterior cingulate cortex (ACC) is a part of the brain's limbic system. Classically, this region has been related to affect, on the basis of lesion studies in humans and in animals. In the late 1980s, neuroimaging research indicated that ACC was active in many studies of cognition. The findings from EEG studies of a focal area of negativity in scalp electrodes following an error response led to the idea that ACC might be the brain's error detection and correction device. In this article, these various findings are reviewed in relation to the idea that ACC is a part of a circuit involved in a form of attention that serves to regulate both cognitive and emotional processing. Neuroimaging studies showing that separate areas of ACC are involved in cognition and emotion are discussed and related to results showing that the error negativity is influenced by affect and motivation. In addition, the development of the emotional and cognitive roles of ACC are discussed, and how the success of this regulation in controlling responses might be correlated with cingulate size. Finally, some theories are considered about how the different subdivisions of ACC might interact with other cortical structures as a part of the circuits involved in the regulation of mental and emotional activity.     

Use of a common software system for collaborative clinical research on attentional processes in schizophrenia and ADHD

MacArthur Network III, consisting of five nodes (locations) and over 100 investigators, was formed in 1983 to conduct collaborative clinical research on risk and protective factors associated with psychiatric disorders. The common measurement of attentional dysfunction associated with two specific disorders (schizophrenia and attention deficit-hyperactivity disorder) was a goal of a subgroup of 11 Network III investigators. In this paper, the experiences with five approaches for implementing common protocols on laboratory computers for collaborative clinical research are described. The reasons for selecting the approach provided by Schneider’s (1988) MEL system are presented and discussed.     

After-school activities and the development of low-income urban children: a longitudinal study.

After-school activities of 194 African American and White children from low-income households were studied from 3rd to 5th grade to determine relations with (a) child, family, and contextual variables and (b) children's adjustment over time. Girls were more likely to engage in academic activities and socializing, whereas boys were more likely to play coached sports. Children who attended after-school programs spent more time on academic and extracurricular activities, whereas children in informal care settings spent more time watching TV and hanging out. Evidence of transactional relations between after-school activities and child adjustment was found. Time spent in activities between 3rd and 5th grades was related to children's adjustment in 5th grade. In addition, child adjustment measured in 3rd grade was associated with time in different activities in 5th grade.     

Mood Management Mail Intervention Increases Abstinence Rates for Spanish-Speaking Latino Smokers

A self-administered mood management intervention program for smoking cessation provided through the mail to Spanish-speaking Latinos resulted in a 23% abstinence rate at 3 months compared to an 11% abstinence rate for a smoking cessation guide alone. Participants (N = 136) were randomly assigned to receive either the cessation guide (the Guía), or the Guía plus a mood management intervention (Tomando Control de su Vida) presented in writing and in audiotape format. At 3 months after random assignment, 16 out of 71 of those assigned to the Guía-plus-mood management condition reported being abstinent (not smoking for at least 7 days) compared to 7 out of 65 in the Guía-only condition (z = 1.8; p = .04, one-tailed). Moreover, those with a history of major depressive episodes, but not currently depressed, reported an even higher abstinence rate in the Guía-plus-mood management condition, compared to the Guía-only condition (31 vs. 11%, z = 1.8, p = .04, one-tailed). We conclude that the mood management mail intervention substantially increases abstinence rates, especially for those with a history of major depressive episodes.     

Lexical access and the brain: anatomical constraints on cognitive models of word recognition.

Recent studies in the cognitive psychology of reading and many other skilled performances have been dominated by models inspired by neural connectivity (e.g., McClelland & Rumelhart, 1986). Such models have not yet begun to consider the accumulating evidence of considerable anatomical localization of component cognitive operations in the human brain (e.g., Posner, Petersen, Fox, & Raichle, 1988). In this article we apply anatomical findings to the job of building computational models of visual word recognition. Brain imaging studies already provide important constraints on how lexical access should be defined in terms of isolable encoding operations that compute the visual form, phonology, and semantics of words. Brain imaging studies also speak to issues of modularity versus interaction between these encoding operations, distribution versus localization of processing within the operations, and orchestration of operations to accomplish different word processing tasks. We conclude that a combined cognitive and anatomical analysis may be of considerable benefit in developing more adequate models of human information processing.     

On the selection of signals

In a previous paper, it was argued that alertness, selectivity (set), and processing capacity (consciousness) could be identified and studied as separate components of attention. The current paper develops this theme by showing that alertness does not affect the buildup of information within the memory system but only the rate at which a later system responds to that information. Thus, in standard reaction-time tasks, increased alertness produces a reduction in reaction ’time but no decrease in errors. In contrast, providing a model of the signal the S is to process improved both speed and accuracy. The,. presence of a model of what the S is to process varies the vertex neural response to that specific signal as compared to a mismatching signal in the first 200–300 msec after its presentation. Three accounts of this effect are: speeded processing of a matching stimulus, habituation of the electrical response to a matching stimulus, and prolonged or enhanced processing of a mismatch. Evidence favors the first of these explanations, but the other two cannot be dismissed as possible contributors to this effect.     

Orienting of attention

Bartlett viewed thinking as a high level skill exhibiting ballistic properties that he called its “point of no return”. This paper explores one aspect of cognition through the use of a simple model task in which human subjects are asked to commit attention to a position in visual space other than fixation. This instruction is executed by orienting a covert (attentional) mechanism that seems sufficiently time locked to external events that its trajectory can be traced across the visual field in terms of momentary changes in the efficiency of detecting stimuli. A comparison of results obtained with alert monkeys, brain injured and normal human subjects shows the relationship of this covert system to saccadic eye movements and to various brain systems controlling perception and motion. In accordance with Bartlett's insight, the possibility is explored that similar principles apply to orienting of attention toward sensory input and orienting to the semantic structures used in thinking.