The Pavlov Department of Physiology: a scientific history

The scientific adventure of the Ivan Pavlov Department of Physiology is traced from Pavlov's and his students pioneer work on "psychic salivation" to the times of the Biological Station at Koltushi. The development of the Department after Pavlov's death is described and the research trends of the three present laboratories (Neurobiology of Integrative Brain Functions, Psychophysiology of Emotions, and Neurodynamic Correction of Psycho Neurological Pathology) are discussed.     

Inhibition and working memory: effect of acute sleep deprivation on a random letter generation task]

The literature contains inconsistent data on the effects of acute sleep deprivation on the superior cognitive functions. The primary purpose of this study is to determine the effectiveness of inhibition, one of the functions of the working memory executive centre (EC), over an extended, 36-hour waking period. Inhibition is a cognitive mechanism whereby individuals ignore non-relevant information recorded in their working memory. We also tested the effects of a 36-hour period of acute sleep deprivation on simple reaction time. Twelve young, healthy volunteers (M = 21.5 years, sigma = 2.3) performed a random generation task involving letters and a simple reaction time psychomotor test over four sessions held at 10-hour intervals. Each participant was assigned a "constant routine." Participants were kept awake in a prone position within a room whose environment was held strictly constant (light, noise, temperature, meals, etc.). This control procedure provided assurance that any variation in participant performance was solely caused by sleep deprivation. The random generation task, nearly two minutes in length, consisted in verbally producing a sequence of 100 letters in a random fashion (i.e. by inhibiting, for example, alphabetical order) and by keeping to a set rhythm. Our assumption was that capacity for inhibition diminished as the number of hours of sleep deprivation increased. The simple reaction test, 10 minutes in length, involved pressing a button as swiftly as possible to cause a black square to disappear from a screen. In this case our assumption was that acute sleep deprivation alters simple reaction time. Analysis of variance (ANOVA) through repeated measures using the "sessions" factor as an intra-subject variable showed no significant changes in randomization indices of the random generation task, contrary to analysis of average simple reaction times. Participants' reaction times deteriorated over the first two minutes of the test during the night they were deprived of sleep. It would seem that the contradictory results of previous studies of the effects of acute sleep deprivation on the inhibition function would be due to errors in factor identification. In conclusion, the inhibition function, as measured during the performance of a brief task, seems to remain intact during an extended, 36-hour waking period. Simple reaction time assessed by means of a brief psychomotor test is affected during a night of sleep deprivation. The working-memory inhibition executive function shows greater resistance to acute sleep deprivation than does psychomotor reaction time for the performance of short tasks.     

From I: A/M to “Who am I?”—Aggregation/Massification and Trauma-Based Affects and Object Relations in Groups: A Response to Earl Hopper

Hopper's portrayal of the fourth basic assumption of Incohesion: Aggregation/Massification has two components: (1) a revision of Turquet's theory of BA Oneness to incorporate the polarity of aggregation and massification stemming from annihilation anxiety; and (2) a conception of the difficult patient as having an encapsulated psychosis. Hopper's theory of the encapsulated psychosis offers an important but incomplete perspective in explaining borderline and narcissistic pathology, as well as psychological trauma. In this response to Hopper, I suggest that the fourth assumption is in fact a still more primitive state of boundary opening and closing. I also see a need to differentiate trauma as such from borderline pathology, and further hold that the relationship between Hopper's British Independent theory and trauma theories based on dissociation needs to be clarified.     

The effects of complexity on jurors' verdicts and construction of evidence

One hundred twenty mock jurors heard 1 of several versions of a civil trial. The tort trial was either high or low in information load and contained evidence that either clearly favored the plaintiffs or was ambiguous. Expert witnesses testified in either technical or less technical language. Verdicts favored the plaintiffs when the evidence was clear and was presented in technical language because technical language enhanced witnesses' credibility when the evidence was clear. Although high information loads and technical language hindered evidence processing, jurors endeavored to comprehend, as indicated by the recall of more facts and alternative constructions of the evidence when that evidence was ambiguous. However. those constructions were of poorer quality, incorporating evidence of lesser probative value.     

Stimulus-determined discrimination mechanisms for color search

Visual attention can be goal driven, stimulus driven, or a combination of the two. Here we report evidence for an unexpectedly stimulus-driven component of visual search for a target defined by color. Observers demonstrated a surprisingly cost-free ability to incorporate multiple classifiers in search for a target of one color from among distractors of other colors. A target color was presented among distractors that could change from trial to trial (intermixed presentation) or that remained constant across all trials in a block (blocked presentation). For blocked presentation, a single search classifier (a mechanism that segregates the target from distractors in color space) could be adopted, whereas for intermixed presentation different classifiers had to be used when the distractor colors changed. The benefit of blocked presentation was very small, suggesting that the appropriate classifier was determined very quickly in trials for which the classifier changed. The results suggest that the stimulus-driven activation of an appropriate stimulus classifier can be very efficient.     

Mathematical engineering and mathematical change 1

In this paper, I introduce and examine the notion of “mathematical engineering” and its impact on mathematical change. Mathematical engineering is an important part of contemporary mathematics and it roughly consists of the “construction” and development of various machines, probes and instruments used in numerous mathematical fields. As an example of such constructions, I briefly present the basic steps and properties of homology theory. I then try to show that this aspect of contemporary mathematics has important consequences on our conception of mathematical knowledge, in particular mathematical growth.     

The history of Russian psychoanalysis and the problem of its periodisation

The formation and spread of the psychoanalytic teaching of Sigmund Freud and his followers is one of the most significant events in the life of the spirit in the twentieth century. The recognition of this as an historical fact--irrespective of its relation to Freud and his ideas--assumes of course and need to gain a proper understanding and appropriate interpretation of psychoanalysis in all its dimensions. Generally speaking, the history of psychoanalysis and the psychoanalytic movement has been researched quite fully, although for a variety of reasons and circumstances there are a number of gaps in it. Perhaps the most important of these is the history of Russian psychoanalysis, which has developed within a country where, at the beginning of the century, Freud's works were translated and published in a most effective and representative way, and where psychoanalytic ideas drew a response both from specialists and among the public at large, although in content and inclination the Russian mentality did not at heart suit a psychoanalytical treatment of man and his culture.