Short- and Long-Term Impact of Receiving Genetic Mutation Results in Women at Increased Risk for Hereditary Breast Cancer

Forty-seven unaffected women from high-risk breast cancer families who had received results for hereditary breast/ovarian predisposition genes between 1 month and 5 years ago were interviewed regarding their experiences. Women responded to open-ended questions. The initial emotional turmoil reported by most was generally short lived. However, the impact of genetic testing went beyond the individual to the extended family and social context, particularly in the short-term. A common theme was the difficulty associated with divulging a result to family members, who were also adjusting to their own result. The majority of carriers reported advantages that were both physical (options for surveillance programs and prophylactic surgery) and emotional (reduced uncertainty, increased awareness of options and knowledge about risk, preparation time). Most carriers reported no change in lifestyle although some reported discovering their mutation status as a positive life-changing experience. Implications for genetic counseling and further research are discussed.     

Alternative Employment Arrangements: A Gender Perspective

In this study we drew on national-level data to investigate the gendered nature of two alternative employment arrangements (independent contractors and temporary agency help), preferences for such arrangements, and the extent to which such arrangements accommodate work/family career quandaries of contemporary workers. Multivariate analyses revealed the perpetuation of gender schema and gendered structures, but this varied by type of alternative employment arrangement. Greater preference for temporary agency employment by married women than by married men derived from women not having to be the primary source of family income, rather than from an effort to balance work and child-rearing responsibilities. There were also gender differences in the tendency of married men and women to be independent contractors; women were less likely to be contractors. However, this alternative employment arrangement offers potential for both men and women to satisfy or challenge other gendered family structures and schema.     

managing the action: sports bookmakers as entrepreneurs

More and more states have moved to legalize various forms of gambling as a viable way to raise substantial revenues. And while some have considered adding sports betting to their menu of games, Nevada continues to be the only state where placing a bet on sports events is legal. This is both puzzling and ironic considering the popularity of gambling and the prominence of sports. Despite the lack of concrete knowledge about illegal sports betting, two justifications for keeping it illegal have dominated the public debate. The first has to do with whether legal sports betting could successfully compete with illegal operations were it to be legalized and the second has to do with a purported link between gambling on sports and organized crime. This paper focuses on the second line of argument and examines the social, organizational, and occupational features of bookmaking. If bookmakers are conduits for organized crime, as is claimed, there should be evidence of this in the day-to-day activities of bookmaking and in the career trajectories of bookmakers. The analysis is based upon interviews with 47 sports bookmakers working in the Rust Belt region. Drawing upon what sports bookies themselves have to say about their experiences in the business and their career trajectories, there appears to be little merit to the organized crime link argument. The analysis suggests that unlike other types of deviance, the social organization of bookmaking insulates bookies from the more typical consequences associated with frequent and prolonged deviant activity, for example, getting arrested, being prosecuted, serving time in prison, and forced association with other criminals. In fact, the findings suggest that bookies are more like entrepreneurs than criminals. While a single study cannot resolve the normative question about whether sports bookmaking should be criminalized, the findings do show that the social construction of bookmaking and bookmakers found in the public debate and popular culture does not reflect the reality of sports bookmaking.     

Attitudes toward women's right to self-determination

Abstract

After briefly describing the purpose, structure, and functions of a typical family planning center, the paper suggests and gives support for a more relationship-centered service delivery system. The major thesis of the paper is that these centers should adopt a system which recognizes and promotes intimate human relationships, and that marriage and family counselors would be highly valuable resources in such a system. The paper stresses the importance of attending to the myriad relationship issues involved in the entire process of enabling individual couples to more effectively plan and control their own fertility. Several ways in which the marriage and family counselor can work with and within the family planning center are outlined.     

Chance,command, and chaos in ancient military engagements 1

The Greeks and the Romans believed that commanders ought to exercise their foresight to preclude risks in combat. They also tried to inculcate and to preserve order in their military systems by the use of initiatory mechanisms, repetitive drill, and replication of the military order in social, economic, and spatial arrangements. In spite of their efforts to minimize entropy within their military units, these systems sometimes underwent chaotic transformations during set‐piece engagements on the battlefield. These set‐piece battles which followed a simple, formulaic pattern provide the data for a case‐study in the behavior of military systems within a relatively simple set of constraints. The results suggest that command functions can have little influence once a system is actively engaged with the enemy and that small effects can drive even simple military systems irreversibly over thresholds into chaos. They illustrate the dangers in any analysis of military phenomena which assumes linear rather than chaotic change. They also suggest that prediction, let alone control, of the course of an engagement is considerably more difficult than is often assumed. It is even difficult to label known outcomes as victories or losses, since the same result may appear differently to two observers occupying different vantage points. Military analysts should take into account values held by society at large.     

Functional and connectivity changes during working memory in Huntington’s disease: 18 month longitudinal data from the IMAGE-HD study

Background

This study aimed to characterize, for the first time, 18 month longitudinal changes in both functional activation and functional connectivity during working memory in premanifest Huntington’s disease (pre-HD) and symptomatic HD (symp-HD).

Methods

Functional magnetic resonance imaging (fMRI) was used to investigate longitudinal changes in neuronal activity during working memory performance via an N-BACK task (0-BACK and 1-BACK) in 27 pre-HD, 17 symp-HD, and 23 control participants. Whole-brain analysis of activation and region-of-interest analysis of functional connectivity was applied to longitudinal fMRI data collected at baseline and 18 months follow-up.

Results

Compared with controls, the pre-HD group showed significantly increased activation longitudinally during 1-BACK versus 0-BACK in the lateral and medial prefrontal, anterior cingulate, primary motor, and temporal areas cortically, and caudate and putamen subcortically. Pre-HD far from onset, compared with controls, showed further longitudinal increases in the right and left dorsolateral prefrontal cortex (DLPFC). Longitudinal increased activation in anterior cingulate and medial primary motor areas were associated with disease burden in the pre-HD group. Moreover, in pre-HD increased activation over time in primary motor and putamen regions were associated with average response time during 1-BACK performance. During 1-BACK, functional connectivity between the right DLPFC and posterior parietal, anterior cingulate, and caudate was significantly reduced over 18 months only in the pre-HD group.

Conclusions

Longitudinal reductions in connectivity over 18 months may represent an early signature of cortico-cortical and cortico-striatal functional disconnectivity in pre-HD, whereas the concomitant increased cortical and subcortical activation may reflect a compensatory response to the demands for cognitive resources required during task performance. Our findings demonstrate that functional imaging modalities have the potential to serve as sensitive methods for the assessment of cortical and subcortical responses to future treatment measures.     

The Work of Feminists is Not Yet Done: The Gender Pay Gap—a Stubborn Anachronism

Lips (2012) critiques the literature, predominantly from the United States, to assess how well human capital theory explains the gender pay gap. Her analysis shows that human capital inputs are an imperfect explanation for the gap and that social psychological influences also provide key explanations. I comment on Lips’s paper using literature from the United States and other English-speaking highly developed countries and, to a lesser extent, from European countries. I elaborate and extend her position, promoting the argument for the effect of social influences and for their interactive and incremental effects. I place the phenomenon of the gender pay gap into a societal context. I borrow from the literature for the effect of gender discrimination on women’s advancement in management to discuss explanatory influences. I extend the inference that the gender pay gap supports and maintains the lesser status of women in society and that it helps to preserve the status quo with respect to gender roles. To explain the gender pay gap, I propose that the development of an integrated theoretical framework is needed. The framework would combine the direct and interactive influences of human capital and social psychological inputs, in the context of a cumulative, incremental pattern that occurs over a person’s working life.     

Homelessness Is Traumatic: Abuse,Victimization, and Trauma Histories of Homeless Men

Homelessness is traumatic, and trauma-informed care is an emerging best practice. Using structured interviews with day shelter clients (N = 152), this study examined trauma among homeless men. The PTSD Checklist (PCL–C) was used to assess for posttraumatic stress disorder (PTSD). Participants’ pattern of PCL–C responses suggested that 23% to 30% screened positive for PTSD. Those with positive PTSD screens had been homeless longer and were more likely to have met time criteria for chronic homelessness. They were significantly more likely to be veterans and to report violent attacks, abuse histories, and mental health problems. Importantly, only 69% of those with positive PTSD screens acknowledged current mental health problems. These individuals were much less likely to report mental health counseling in the prior year.     

Presenting Different Selves to Different People: Self-Presentation as a Function of Relationship Type and Contingent Self-Esteem

Past work has established a connection between self-esteem and self-presentation; however, research has not explored how self-esteem that is contingent on one's relationship may influence self-presentational tactics in that relationship. Across two studies, undergraduate students reported on the extent to which their self-esteem depended on their friendship and romantic relationship, as well as the extent to which they engaged in self-presentation behaviors in those relationships. The results suggest that relationship-specific contingent self-esteem predicts relationship-specific self-presentation; however, friendship-contingent self-esteem predicted self-presentation in both friendships and romantic relationships. These results suggest that individuals are keenly and differentially attuned to qualitatively different relationships, and when perceiving potential problems, they attempt to remedy those through their self-presentations. Furthermore, results indicate the possibility that self-esteem tied to a particular relationship may not be as important as self-esteem based more generally on one's relationships.