Neurocognitive Functioning in Depressed Young People: A Systematic Review and Meta-Analysis

Background: Depression is among the most common mental health problems for young people. In adults, depression is associated with neurocognitive deficits that reduce the effectiveness of treatment and impair educational and vocational functioning. Compared to adults, less is known about the neurocognitive functioning of young people with depression, and existing research has reported inconsistent findings. Method: This systematic review and meta-analysis synthesized the literature on neurocognitive functioning in currently depressed youth aged 12–25 years in comparison to healthy controls. Results: Following a systematic review of the literature, 23 studies were included in the meta-analysis. Poorer performance in the domains of attention (SMD: .50, 95% CI: .18–.83, p?=?.002), verbal memory (SMD: .78, 95% CI: .50–1.0, p?<?.001), visual memory (SMD: .65, 95% CI: .30–.99, p?<?.001), verbal reasoning/knowledge (SMD: .46; 95% CI: .14–.79; p?<?0.001) and IQ (SMD: .32; 95% CI: .08–.56; p?=?0.01) were identified in depressed youth. Relative weaknesses in processing speed/reaction time and verbal learning were also evident, however, these findings disappeared when the quality of studies was controlled for. Moderator analysis showed a tendency for poorer set-shifting ability in younger depressed participants relative to controls (although non-significant; p?=?.05). Moderator analysis of medication status showed taking medication was associated with poorer attentional functioning compared to those not taking medication. Conclusion: The findings suggest that currently depressed young people display a range of neurocognitive weaknesses which may impact treatment engagement and outcome. The findings support the need to consider neurocognitive functioning when treating youth with depression.     

A Conceptual Framework for Understanding the Stigmatization of Children of Incarcerated Parents

Stigmatization is often listed as one of the adverse consequences of parental incarceration; yet, there is very little research on this phenomenon. We address this knowledge deficit by providing a conceptual model of stigmatization and describing how it may apply to children with parents in jail or prison. This model helps to explain why families conceal the fact that a child’s parent is incarcerated; the potentially protective function of social withdrawal; possible links between stigmatization and childhood emotional and behavioral problems; how fear of stigmatization may impede help seeking; and the possibility for research and advocacy to contribute to the stigmatization of children who experience parental incarceration. It also helps to define specific aspects of stigmatization requiring further study.     

Fechner, information, and shape perception

How do retinal images lead to perceived environmental objects? Vision involves a series of spatial and material transformations—from environmental objects to retinal images, to neurophysiological patterns, and finally to perceptual experience and action. A rationale for understanding functional relations among these physically different systems occurred to Gustav Fechner: Differences in sensation correspond to differences in physical stimulation. The concept of information is similar: Relationships in one system may correspond to, and thus represent, those in another. Criteria for identifying and evaluating information include (a)?resolution, or the precision of correspondence; (b)?uncertainty about which input (output) produced a given output (input); and (c)?invariance, or the preservation of correspondence under transformations of input and output. We apply this framework to psychophysical evidence to identify visual information for perceiving surfaces. The elementary spatial structure shared by objects and images is the second-order differential structure of local surface shape. Experiments have shown that human vision is directly sensitive to this higher-order spatial information from interimage disparities (stereopsis and motion parallax), boundary contours, texture, shading, and combined variables. Psychophysical evidence contradicts other common ideas about retinal information for spatial vision and object perception.     

Age,working memory,and the Tower of London task

The current study explores the role of three components of working memory in age differences in an executive task, the Tower of London (TOL). The TOL task is sensitive to frontal lobe damage, and is widely used to measure planning ability. Dual tasks were used to test the involvement of the phonological loop (articulatory suppression), visuospatial buffer (pattern tapping), and central executive (random generation) in age effects on the TOL. Older adults showed greater reliance than young on domain-specific verbal and spatial memory components in performing the TOL. In terms of executive function, qualitatively different interference patterns were seen in young and old participants. However, the validity of using random generation tasks to assess executive function in older populations can be questioned. For older participants, performing the TOL loads all components of working memory, whereas for the younger participants the TOL more specifically loads executive functioning.     

Job context, selection decision outcome, and the perceived fairness of selection tests: biodata as an illustrative case

S. W. Gilliland (1993) has proposed a model of perceived selection system fairness to help understand applicants' prehire and posthire behavior. The present study aimed to verify and extend his framework by investigating the role of job context in the formation of fairness perceptions of biodata. A sample of 255 students (108 men, 147 women) completed an operational biodata instrument, believing that it would be used to hire persons for either international, local, or unspecified entry-level managerial positions. Participants were then presented with outcome information (selected or rejected for further consideration). Consistent support was found for the research hypotheses derived from the Gilliland model. Participants' perceptions of the fairness and job relatedness of biodata were affected by the selection context and decision outcome. The importance of considering selection context in assessments of perceived test fairness is discussed.     

Variations in the relationship between radius of curvature and velocity as a function of joint motion

A power law describes the relationship between the geometric properties of a trajectory (radius of curvature) and movement kinematics (tangential velocity) in curved drawing movements. Although the power law is a general law of motion, there are conditions under which it degrades. In particular, the power law may be less explanatory of movements around certain joints. The present study considered how varying motion around different joints influenced the fit of the power law. Motions associated with finger and wrist, or elicited by an isometric force production task, were compared. The power law was most explanatory of finger motion and isometric production and least explanatory of wrist motion. The fit of the power law for finger and wrist motion suggested separate laws for each joint system. Since the fit of the power law was better for finger than for wrist motion, there is some suggestion that the power law better explains motion around fewer or simpler joint systems.     

Psychophysiological mediators of caregiver stress and differential cognitive decline

The authors examined relationships between chronic stress and cognitive decline and whether such relationships were mediated by psychophysiological factors. Ninety-six caregivers of spouses with Alzheimer's disease (AD) were compared with 95 similar noncaregiver spouses. All were free of diabetes. Although the groups started similarly, over 2 years caregivers declined by a small but significant amount (1 raw score point and 4 percentile points, each p<.05) on Shipley Vocabulary. In contrast, noncaregivers did not change. Higher hostile attribution (beta=-.09; p<.05) and metabolic risk (beta=-.10; p<.05) in caregivers mediated the cognitive decline. This is the first study of cognitive decline and mediators in caregivers. This work has implications for caregiver and care-recipient health and for research on cognition, psychophysiology, diabetes, and AD.     

Nursing and psychological treatments

Presents a comment on "Psychological Treatments" by D. H. Barlow. In his article, Barlow pointed to the need "to solidify the identification of psychology as a health care profession" by changing the terminology of practice in the health care context from psychotherapy to psychological treatments and suggested that the only persons qualified to carry out such interventions are doctoral-level psychologists. Unfortunately, there was no discussion of the health care professionals who already provide psychological treatments in health care settings and their contribution to the evidence base supporting such treatment. The authors find several aspects of the article to be problematic. Overall, the authors feel that suggesting that psychology should claim treatment of psychological disorders and psychological components of physical disorders in health care settings as exclusively its own domain ignores the research and clinical contributions of others.     

The role of the bereavement group in the face of 9/11: a self-psychology perspective

The sudden traumatic loss of a spouse equates to an assault on self and the loss of both an internal and external self-object. Mourning requires compensatory self-objects to help in the restoration of self and in the creation of new self-structure. The catastrophe of 9/11 not only assaulted thousands with unanticipated traumatic loss, but also devastated the usual networks of support. In this light, the bereavement group became a valuable venue for self-restoration and recovery. In her group work with 9/11 corporate and uniformed service widows, the author applies a self-psychology perspective that considers that empathic immersion not only affords safety and stabilization, but the opportunity to have self-object needs met in a process that restores and develops self-structure. She proposes the bereavement group as a cohesive self-object milieu serving mirroring, twinship, and idealizing needs. Drawing upon clinical examples, she illuminates the capacity of the group to establish safety, regulate affect, reduce isolation and shame, rekindle memory, and foster coping skills. As such, the group affords a restoration of the assaulted self, an integration of the loss, and an emerging redefinition of self.     

Convergence of biological and psychological perspectives on cognitive coordination in schizophrenia

The concept of locally specialized functions dominates research on higher brain function and its disorders. Locally specialized functions must be complemented by processes that coordinate those functions, however, and impairment of coordinating processes may be central to some psychotic conditions. Evidence for processes that coordinate activity is provided by neurobiological and psychological studies of contextual disambiguation and dynamic grouping. Mechanisms by which this important class of cognitive functions could be achieved include those long-range connections within and between cortical regions that activate synaptic channels via NMDA-receptors, and which control gain through their voltage-dependent mode of operation. An impairment of these mechanisms is central to PCP-psychosis, and the cognitive capabilities that they could provide are impaired in some forms of schizophrenia. We conclude that impaired cognitive coordination due to reduced ion flow through NMDA-channels is involved in schizophrenia, and we suggest that it may also be involved in other disorders. This perspective suggests several ways in which further research could enhance our understanding of cognitive coordination, its neural basis, and its relevance to psychopathology.