Irrelevant sensory stimuli interfere with working memory storage: Evidence from a computational model of prefrontal neurons

The encoding of irrelevant stimuli into the memory store has previously been suggested as a mechanism of interference in working memory (e.g., Lange & Oberauer, Memory, 13, 333–339, 2005; Nairne, Memory & Cognition, 18, 251–269, 1990). Recently, Bancroft and Servos (Experimental Brain Research, 208, 529–532, 2011) used a tactile working memory task to provide experimental evidence that irrelevant stimuli were, in fact, encoded into working memory. In the present study, we replicated Bancroft and Servos’s experimental findings using a biologically based computational model of prefrontal neurons, providing a neurocomputational model of overwriting in working memory. Furthermore, our modeling results show that inhibition acts to protect the contents of working memory, and they suggest a need for further experimental research into the capacity of vibrotactile working memory.     

Confounding of Big Five Personality Assessments in Emotional Disorders by Comorbidity and Current Disorder

Foremost cross‐sectional studies of personality in common mental disorders show similar Big Five trait profiles [i.e. high neuroticism (N), low conscientiousness (C) and low extraversion (E)]. It remains undecided whether this lack of distinct personality profiles is partly due to comorbidity among disorders or contamination by current state. Using data from the Netherlands Study of Depression and Anxiety, we investigated 1046 participants with panic disorder (PD), social anxiety disorder (SAD) and/or major depressive disorder (MDD) and 474 healthy controls. Personality traits at baseline and two‐year follow‐up were assessed with the NEO‐Five Factor Inventory. The Composite International Diagnostic Interview was used to determine the presence of emotional disorders at baseline and at two‐year follow‐up; the Life Chart Interview determined symptom severity in the month prior to baseline and during follow‐up. By analysing pure cases and investigating the effects in remitted cases, PD participants were found to be higher in N, but not lower in E and C than controls. Pure PD participants were also lower in N and higher in E than SAD and MDD participants. Both SAD and MDD participants were characterized by high levels of N and low levels of E, irrespective of comorbidity or current disorder state. Future studies should be more attentive to confounding of personality profiles by comorbidity and state effects. Copyright © 2012 John Wiley & Sons, Ltd.     

Optimizing treatment of schizophrenia. Enhancing affective/cognitive and depressive functioning

Recognition and treatment of schizophrenia has largely focused on positive symptoms of the disorder, such as delusions, hallucinations, and disorganization. However, other important symptoms, such as depression, cognition, and social functioning, have not received comparable attention. Fifty percent of schizophrenic patients suffer from comorbid depression, which is a major risk factor for suicide in this population, while 10% to 25% suffer from comorbid obsessive-compulsive disorder. Cognitive deficits commonly observed in patients with schizophrenia include problems with concentration, attention, and memory, as well as problem-solving and verbal skills. These deficits are observed at early stages of the illness and can predict deficits in functional capabilities, such as occupational and social skills, educational attainment, and the ability to live independently. The severity of such impairments affects all patient in this population, including up to 10% of patients working full time and up to one third of those working part time. In light of the debilitating effects of depression, cognitive impairment, and other aspects of affective functioning on the quality of life of patients with schizophrenia, physicians need to partner with their patients to address these concerns and determine an appropriate treatment regimen. This can be done with simple functional-based cognitive questioning, the use of evidence-based psychosocial practices, and psychoeducation on the many pharmacotherapeutic options. It is recommended that depressive or suicidal symptoms of schizophrenia be treated with an antidepressant or mood stabilizer only if the symptoms have not subsided after treatment of the psychosis with an atypical antipsychotic. Additionally, relative to older medications, atypicals have demonstrated benefit in improving some of the cognitive impairments.     

Does psychology make a significant difference in our lives?

The intellectual tension between the virtues of basic versus applied research that characterized an earlier era of psychology is being replaced by an appreciation of creative applications of all research essential to improving the quality of human life. Psychologists are positioned to "give psychology away" to all those who can benefit from our wisdom. Psychologists were not there 35 years ago when American Psychological Association (APA) President George Miller first encouraged us to share our knowledge with the public. The author argues that psychology is indeed making a significant difference in people's lives; this article provides a sampling of evidence demonstrating how and why psychology matters, both in pervasive ways and specific applications. Readers are referred to a newly developed APA Web site that documents current operational uses of psychological research, theory, and methodology (its creation has been the author's primary presidential initiative): www.psychologymatters.org.     

Parent-School and Community Partnerships in Children's Mental Health: Networking Challenges, Dilemmas, and Solutions

Inter-agency collaboration, service coordination, and the creation of successful partnerships among parents, teachers, and human services professionals continues to be a challenge for the development of responsive community-based systems of care for at-risk youth and their families. We explore how one inner-city neighborhood struggles to create successful community partnerships through traditional networking strategies. Our findings identify networking strategies that appear to work and those that do not. Recommendations for improving communication are provided.     

How Truth Behaves When There’s No Vicious Reference

In The Revision Theory of Truth (MIT Press), Gupta and Belnap (1993) claim as an advantage of their approach to truth “its consequence that truth behaves like an ordinary classical concept under certain conditions—conditions that can roughly be characterized as those in which there is no vicious reference in the language.” To clarify this remark, they define Thomason models, nonpathological models in which truth behaves like a classical concept, and investigate conditions under which a model is Thomason: they argue that a model is Thomason when there is no vicious reference in it. We extend their investigation, considering notions of nonpathologicality and senses of “no vicious reference” generated both by revision theories of truth and by fixed-point theories of truth. We show that some of the fixed-point theories have an advantage analogous to that which Gupta and Belnap claim for their approach, and that at least one revision theory does not. This calls into question the claim that the revision theories have a distinctive advantage in this regard.     

Word use of outpatients with a personality disorder and concurrent or previous major depressive disorder

In a recent study, Rude, Gortner, and Pennebaker (2004) found word use to be related to depression and vulnerability to depression in the essays of college students. We sought to replicate and extend these findings in a clinical sample. Written essays of 304 psychiatric outpatients with a personality disorder and a mixed psychiatric profile on DSM-IV axis-I and 108 healthy controls were examined with word count software. Data on the tendency to be discrepant about the current self compared to a more ideal self were also gathered. We found that psychiatric outpatients in general used more words referring to the self and negative emotion words and fewer positive emotion words, compared to healthy controls. However, word-use proved unrelated to depression specifically. Actual-ideal self discrepancies were related to patient status and to current depression. Contrary to our hypothesis, these discrepancies did not correlate with the use of words referring to the self. We conclude that the negative content and self-focus of written essays and high levels of discrepancy reflect a negative thinking style that is common to a range of psychiatric disorders rather than being specific to depression.     

PREVENTING BACK INJURIES IN HOSPITAL SETTINGS: THE EFFECTS OF VIDEO MODELING ON SAFE PATIENT LIFTING BY NURSES

This study evaluated video scoring and feedback about scoring as a safety intervention among 6 nursing staff. The dependent variable was safety behavior on one‐person transfers. Following baseline, 5 nursing staff participated in an information phase. A video scoring phase was then introduced for all 6. A feedback phase was added for 2 participants. All participants experienced treatment withdrawal. Information resulted in improvements for all 5 participants who received it. Further improvements were observed during video scoring for the 5 participants who improved following information. No improvements were observed for the participant who received only video scoring. Safety feedback further improved safety for the 2 participants who received it. However, participants' behavior returned to video scoring levels during withdrawal.     

Period and Cohort Effects on Religious Nonaffiliation and Religious Disaffiliation: A Research Note

Period and cohort effects on reports of no religious preference and religious disaffiliation are estimated. Results show that by 2006, the probability of reporting no religious preference had risen to almost .16. Additionally, the growing proportion of Americans raised with no religious preference substantially influences the increase in reporting no religious preference. Two recently developed analysis techniques for disentangling period and cohort effects are used: intrinsic estimator models and cross‐classified, random‐effects models. Results show (1) period‐based increases in the probability of reporting no religious preference from 1990 to 2006, (2) across‐cohort increases in no religious preference beginning with those born in the 1940s, and (3) a decline in the likelihood of religious disaffiliation (being raised with a religious preference but currently reporting no religious preference) for those born in the 1960s and 1970s compared to those born between 1945 and 1959.     

Contour entropy: a new determinant of perceiving ground or a hole

Figure-ground perception is typically described as seeing one surface occluding another. Figure properties, not ground properties, are considered the significant factors. In scenes, however, a near surface will often occlude multiple contours and surfaces, often at different depths, producing alignments that are improbable except under conditions of occlusion. We thus hypothesized that unrelated (high entropy) lines would tend to appear as ground in a figure-ground paradigm more often than similarly aligned ordered (low entropy) lines. We further hypothesized that for lines spanning a closed area, high line entropy should increase the hole-like appearance of that area. These predictions were confirmed in three experiments. The probability that patterned rectangles were seen as ground when alternated with blank rectangles increased with pattern entropy. A single rectangular shape appeared more hole-like when the entropy of the enclosed contours increased. Furthermore, these same contours, with the outline shape removed, gave rise to bounding illusory contours whose strength increased with contour entropy. We conclude that figure-ground and hole perception can be determined by properties of ground in the absence of any figural shape, or surround, factors.