On the Ethics of Facial Transplantation Research

Transplantation continues to push the frontiers of medicine into domains that summon forth troublesome ethical questions. Looming on the frontier today is human facial transplantation. We develop criteria that, we maintain, must be satisfied in order to ethically undertake this as-yet-untried transplant procedure. We draw on the criteria advanced by Dr. Francis Moore in the late 1980s for introducing innovative procedures in transplant surgery. In addition to these we also insist that human face transplantation must meet all the ethical requirements usually applied to health care research. We summarize the achievements of transplant surgery to date, focusing in particular on the safety and efficacy of immunosuppressive medications. We also emphasize the importance of risk/benefit assessments that take into account the physical, aesthetic, psychological, and social dimensions of facial disfiguration, reconstruction, and transplantation. Finally, we maintain that the time has come to move facial transplantation research into the clinical phase.     

Assessing the Factorial Validity of the Attitudes and Belief Scale 2-Abbreviated Version: A Call for the Development a Gold Standard Method of Measuring Rational and Irrational Beliefs

Rational emotive behaviour therapy (REBT) does not possess a measure of rational and irrational beliefs that meets internationally recognised standards for acceptable psychometric properties. Without such a measure the theory/practice of REBT cannot be rigorously evaluated, thus undermining its scientific veracity. The current study investigates the validity and reliability of a recently developed measure of rational and irrational beliefs: the Attitudes and Belief Scale 2-Abbreviated Version (ABS-2-AV). University students from three countries completed the ABS-2-AV (N = 397). An alternative models framework using confirmatory factor analysis indicated that a theoretically consistent eight-factor model of the ABS-2-AV provided the best fit of the data. A number of post hoc modifications were required in order to achieve acceptable model fit results, and these modifications revealed important methodological limitations with the ABS-2-AV. Results indicated that the validity of the ABS-2-AV was undermined due to items measuring both the psychological process of interest (rational and irrational beliefs) and the context in which these beliefs processes are presented. This is a serious methodological limitation of the ABS-2 and all questionnaires derived from it, including the ABS-2-AV. This methodological limitation resulted in the ABS-2-AV possessing poor internal reliability. These limitations are discussed in relation to the broader REBT literature and the impact such problems have on research and practice. A call is made for REBT researchers to come together to develop a “gold standard” method of assessing rational and irrational beliefs that meets international standard for psychometric excellence.     

The End of the Solidly Democratic South: The Impressionable‐Years Hypothesis

The partisan realignment of the White South, which transformed this region from being solidly Democratic to being the base of the Republican Party, has been the focus of much scholarship. Exactly how it occurred is unclear. Widespread individual‐level attitude changes would be contrary to the well‐known within‐person stability of party identification. However, according to the impressionable‐years hypothesis, events that occur during adolescence and early adulthood may have a lasting impact on later political attitudes. This would suggest that cohort replacement may be driving partisan realignment. We test this possibility using data from the American National Election Studies from 1960 to 2008. Consistent with the impressionable‐years hypothesis, Southern Whites from the pre‐Civil Rights cohort (born before 1936) maintained their Democratic Party identification longer than their younger counterparts. However, all cohorts in the South have changed their partisan attitudes at comparable rates over time, contrary to the impressionable‐years hypothesis. These data suggest that the partisan realignment of the South was driven by both cohort replacement and within‐cohort attitude change. More targeted case studies of older cohorts living through the civil rights era, and of younger cohorts in the post‐Reagan era, yield results generally consistent with the impressionable‐years hypothesis. More generally, our findings suggest that very large scale events are required to disrupt the normal continuity of party identification across the life span.     

Encouraging electricity savings in a university residential hall through a combination of feedback, visual prompts, and incentives

This experiment investigated the combined use of visual prompts, daily feedback, and rewards to reduce electricity consumption in a university residential hall. After a 17-day baseline period, the experimental intervention was introduced in the intervention hall, and no change was made in the control hall. Energy usage decreased in the intervention hall, but energy usage did not change appreciably in the control hall. In the intervention hall, mean daytime and nighttime savings were 16.2% and 10.7%, respectively, compared to savings of 3.8% (day) and 6.5% (night) in the control hall.     

Engaging Narratives and the Limits of Lay Ethics: Introduction

How can one discover the ethical issues associated with nanotechnologies? One heuristic is to tend closely to the ethical reflections of lay publics and the ways in which these are informed by experience with technological innovation, technology governance, and the (broken) promises of visionary science and technology. A close collaboration between social scientists and philosophers took this heuristic to its limits: On the one hand, it achieved remarkably fine–grained insights into public reflection about nanotechnologies. On the other hand, a philosophical analysis of these reflections makes apparent that there is a profound disconnect between the lay ethics rooted in public talk and the ethical and normative commitments that are embedded in nanotechnological research programs and practices. Accordingly, critical engagement with the ways in which ordinary people try to make sense of nanotechnologies constitutes a novel heuristic for the discovery of ethical issues. This introduction and the subsequent four papers show this heuristic at work.     

Construct Validity of the Balloon Analogue Risk Task (BART): Relationship with MDMA Use by Inner-City Drug Users in Residential Treatment

In a program of research assessing the validity of the balloon analogue risk task (BART; C. W. Lejuez et al., 2002) as a measure of risk taking, the BART was administered to a sample of inner-city drug users in residential treatment (n = 76). Construct validity of the BART was evaluated by measuring risk-taking behavior and 3,4-methylenedioxymethamphetamine (MDMA) use while controlling for self-reported impulsivity, sensation seeking, polysubstance use, and demographic variables. Supporting the construct validity of the BART, while controlling for interrelated variables in the context of logistic regression analyses, (BART) risk-taking propensity accounted for significant incremental variance in differentiating MDMA users from non-users. BART scores, polysubstance use, and younger age were most associated with MDMA use, and together these variables were associated with 91% classification accuracy in predicting MDMA use.     

Stimulus-response compatibilities during top-bottom discriminations.

Participants indicated whether a small dot was located near the top or bottom pole of a rotated object. Response times increased as a function of object orientation more for top trials than for bottom trials. The interaction between orientation and response was shown to be due to a relationship between response times and the dot's height on the screen. The orientation effect was influenced, positively and negatively, by a vertical arrangement of the response keys depending on whether the upper or lower key was used for the top response. Horizontal key placement produced an intermediate orientation effect, with asymmetries of about 180 degrees depending on which hand was used for top responses. This task appears to reflect spatial stimulus-response compatibilities more than object processing.     

Process causality and asymmetry

Process theories of causality seek to explicate causality as a property of individual causal processes. This paper examines the capacity of such theories to account for the asymmetry of causation. Three types of theories of asymmetry are discussed; the subjective, the temporal, and the physical, the third of these being the preferred approach. Asymmetric features of the world, namely the entropic and Kaon arrows, are considered as possible sources of causal asymmetry and a physical theory of asymmetry is subsequently developed with special reference to the questions of objectivity and backwards causation.An earlier draft of this paper was read at the A.A.P. conference at the University of Sydney, June, 1990. The author would like to thank Peter Menzies and Huw Price for their helpful comments.