关注肿瘤患者避免过度诊疗——解析ASCO大会关于肿瘤诊疗的5项建议

现代肿瘤的诊疗水平已经有了长足的进步,先进的诊断技术使得很多肿瘤得以早期发现并积极治疗,很多晚期患者也不再面临无药可用的境地,但由于临床医生的认识存在偏差,存在过度诊断和过度治疗的问题,进而给患者带来不必要的负担和痛苦。美国临床肿瘤学会（ASC0）年会上发布了一篇名为“ASCO为改善肿瘤治疗质量及医疗花费的5项建议”的文章,特别提出要重视五项临床广泛应用、花费较大,但缺乏高级临床证据的肿瘤治疗或干预措施,也提示我们需要充分评估,综合思考,为合适的患者提供正确的诊治方案,才能给患者带来更大的获益。     

辩证情绪:研究方法及展望

有关辩证情绪的实证研究已经成为情绪研究中的一个新的热点问题,并从一个本土心理学的研究领域演变为主流心理学的研究课题。辩证情绪是指积极和消极情绪的共存。文章对辩证情绪的研究方法进行了回顾,主要包括辩证情绪研究范式的演变、辩证情绪的诱发方法、辩证情绪的测量方法以及辩证情绪的计算方法,并对不同的研究方法的优缺点及其贡献进行了比较和分析。最后,文章对辩证情绪研究方法的未来发展提出了展望。     

最大信息量法在CCSPC评分中应用的效度证据

采用基于最大信息量法的多维项目反应理论模型估计计算机模拟心理咨询病例系统（CCSPC）的合成分数及四个模块分数,并收集效标效度证据、成长变化效度证据和内容效度证据,结果表明：五个指标与心理咨询师考试三级技能成绩的相关均达到显著,且高于其与三级理论成绩的相关;所有指标得分均随着心理学学历升高而升高;多数指标分数随心理学本科年级提高而提高;获得心理咨询师资格认证的被试在CCSPC上有更高的得分.     

Problem Finding and Contradiction: Examining the Relationship Between Naive Dialectical Thinking,Ethnicity, and Creativity

This research examined the association between naive dialectical thinking and creativity, measured as originality in problem construction and reframing (types of problem finding). Ethnic identity (Caucasian vs. Asian/Asian American) was examined as a moderator. Two correlational studies and one experimental study revealed a complex pattern of results: For problems with low inherent contradiction, naive dialectical thinking decreased originality on problem finding tasks, whereas for tasks with higher contradiction, there was no or even a slight positive effect. Furthermore, these relationships were found for Caucasian participants but not for Asian or Asian American participants. This research built upon the long-standing notion that dialectical thinking is positively associated with creativity, but suggests the relationship might be culture-, task-, and process-specific. The nature of dialectical thinking as involving the acceptance of contradiction or necessitating the resolution of tension should be explored.     

The Role of Sketching States in the Stimulation of Idea Generation: An Eye Movement Study

Sketching is widely used in design to generate creative ideas. Design studies present stimuli during sketching to enhance creativity. This study examines the effect of stimuli presented during different sketching states, especially of those presented during the stuck period. It conducted a sketching experiment that enrolled 41 students with an average of 5.7 years’ practice in industrial design. The sketching with stimuli presented at regular intervals, those with stimuli presented during the stuck period, and those without stimulus were compared. Eye movements during the sketching processes were recorded. The attention to stimuli, and the direct applications of stimuli to design ideas, and the idea connection and idea differentiation were analyzed. Participants sketching with stimuli presented during the stuck period had a higher sketching quality, compared with those in other experimental conditions. They fixated longer on stimuli, built more links among related ideas, and had a more differentiated and balanced exploration. This study then proposed the mechanisms of stimuli processing. The stimuli presented at regular intervals were stored and acted as additional memory. The stimuli presented during the stuck period were dissected and acted as supporter, inducing a more creative sketching.     

Knowledge and economic growth—creativity,learning and knowledge utilization

The purpose of this study is to discuss the dynamic interdependence of knowledge and economic growth. We show that the traditional economics, which treats knowledge as parameters and is mainly developed within linearized, stable and static frameworks can hardly explain the modern economic complexity. We argue that it is necessary to treat creativity, learning and knowledge utilization as endogenous dynamic processes of social and economic evolution. To handle with the complicated dynamic interdependence of wealth and knowledge accumulation, we need to apply genuine nonlinear dynamic theory. In particular, we discuss possible benefits of government's intervention in education and science to the society when the social and economic evolution is characterized of nonlinearity, instability and multi‐equilibria.     

A Computationally Efficient State Space Approach to Estimating Multilevel Regression Models and Multilevel Confirmatory Factor Models

Although the state space approach for estimating multilevel regression models has been well established for decades in the time series literature, it does not receive much attention from educational and psychological researchers. In this article, we (a) introduce the state space approach for estimating multilevel regression models and (b) extend the state space approach for estimating multilevel factor models. A brief outline of the state space formulation is provided and then state space forms for univariate and multivariate multilevel regression models, and a multilevel confirmatory factor model, are illustrated. The utility of the state space approach is demonstrated with either a simulated or real example for each multilevel model. It is concluded that the results from the state space approach are essentially identical to those from specialized multilevel regression modeling and structural equation modeling software. More importantly, the state space approach offers researchers a computationally more efficient alternative to fit multilevel regression models with a large number of Level 1 units within each Level 2 unit or a large number of observations on each subject in a longitudinal study.     

Sensitivity of Fit Indices to Misspecification in Growth Curve Models

This study investigated the sensitivity of fit indices to model misspecification in within-individual covariance structure, between-individual covariance structure, and marginal mean structure in growth curve models. Five commonly used fit indices were examined, including the likelihood ratio test statistic, root mean square error of approximation, standardized root mean square residual, comparative fit index, and Tucker-Lewis Index. The fit indices were found to have differential sensitivity to different types of misspecification in either the mean or covariance structures with severity of misspecification controlled. No fit index was always more (or less) sensitive to misspecification in the marginal mean structure relative to those in the covariance structure. Specifying the covariance structure to be saturated can substantially improve the sensitivity of fit indices to misspecification in the marginal mean structure; this result might help identify the sources of specification error in a growth curve model. An empirical example of children's growth in math achievement (Wu, West, &; Hughes, 2008 Wu, W., West, S. G. and Hughes, J. N. 2008. Effect of retention in first grade on children's achievement trajectories over four years: A piecewise growth analysis using propensity score matching.. Journal of Educational Psychology, 100: 727–740. [Crossref], [PubMed], [Web of Science ®] , [Google Scholar]) was used to illustrate the results.     

Evaluating Word in Phrase: The Modulation Effect of Emotional Context on Word Comprehension

The present study aims to explore the influence of emotional context on word evaluation. Participants were asked to read an “adjective + noun” phrase, where the adjective could be a positive or negative word, and the noun could be a positive, neutral or negative word, and then to make an emotional evaluation on the emotional tone of the target noun based on a 9-point Likert scale. In a control condition, an isolated noun was presented with no context. Results showed that positive context made the evaluation of target words bias toward positive tone, while negative context shaped the evaluation of target words toward negative tone. The modulatory effect of negative context was greater than that of positive context in shaping evaluation of emotional words with opposite valence. Moreover, the modulatory effect of emotional context was constrained by the inherent meaning of target word. The present study demonstrated the flexibility as well as the relative stability of emotional meaning of word.     

不同线索下特质焦虑个体的返回抑制

焦虑与注意偏向的研究是近年来情绪与认知领域的热点。为探讨特质焦虑个体的注意偏向特点及其返回抑制能力是否受不同线索的调节, 采用特质焦虑量表筛选高特质焦虑大学生29名, 低特质焦虑大学生28名完成线索-靶子任务。要求被试在提示线索消失后, 对位置进行快而准地辨别反应, 分别探索中性和情绪性提示线索下被试的返回抑制。结果发现：(1)在中性线索条件下, 高焦虑个体平均反应时慢于低焦虑个体。(2) 在情绪线索条件下, 高焦虑个体在负性线索下的反应时小于在正性线索下的反应时; 高、低焦虑个体在各种SOA条件下均出现了返回抑制, 但各组返回抑制量受到情绪线索的调节：在正性情绪线索条件下, 两组返回抑制量没有显著差异; 在负性情绪线索下, 高焦虑个体返回抑制量显著小于低焦虑个体。这表明, (1)焦虑个体的注意偏向受到刺激信息的影响：只对负性情绪线索出现注意警觉; (2)只有在涉及负性情绪信息时高、低焦虑个体返回抑制能力才有差异, 高焦虑个体存在对负性情绪线索的抑制困难。