平板运动试验心脏变时功能不全对冠心病的诊断价值

为探讨平板运动试验(treadmill exercise testing,TET)心脏变时功能不套(chronotropic incompetence,CI)对冠心病(coronary heart disease,CHD)的诊断价值,分析112例临床拟诊冠心病患者,先后均行TET及冠状动脉造影检查(coronary angiography,CAG),并按CAG结果分为CHD组和非CHD组,分析比较两组间心脏变时性指标;并对传统的ST标准、CI指标及两项指标联合诊断冠心病的敏感性、特异性、准确性进行比较.运动后最大心率小于预测最大心率的85％和变时性指数(chronotropic response index,CRI)小于0.8为心脏变时功能不全.结果表明CHD组运动后最大心率、CRI两种变时功能不全的指标均低于非CHD组(P＜0.01);与传统的ST段标准相比,CI指标诊断CHD的敏感性、特异性、准确性无明显差异(P＞0.05),而两项指标联合诊断冠心病的敏感性与传统的ST段标准相近,特异性及准确性显著高于传统ST标准,差异有统计学意义(P＜0.05).故CI指标是诊断CHD的重要价值的指标,可以提高TET对CHD的诊断率.     

Correlation between ductility and work function in NiAl–Ce–Cr alloys

In spite of many superior high-temperature properties of intermetallics, it has been difficult to understand their intrinsic brittleness. To eliminate or improve the embrittlement, the conventional alloying technique based on the trial-and-error method is still the most effective and practical. However, it remains a main challenge for both physicists and materials scientists to provide either an alloying principle or a deep insight into its toughening mechanism at an atomic or electronic level. This letter reports a simple experimental approach that uses work function (WF) as a sensitive indicator of the role of alloying in changing mechanical behavior. NiAl is chosen as a typical example. It is found that with the addition of Cr and Ce, the ductility of NiAl increases significantly. Such an increase in ductility corresponds to a concomitant decrease in the WF, which is attributed to a change in the nature of the atomic bonding or in the electronic structure induced by the alloying. This fundamental understanding on the embrittlement nature of NiAl could provide some alloying guidelines or principles for other intermetallics.     

Emotion and appraisal: A study using ecological momentary assessment

This study employed Ecological Momentary Assessment to test predictions from appraisal theories of emotion about the relationships between emotions and appraisals, using a sample of police officers from Singapore. Strong support was obtained for the predictions, thus demonstrating ecological validity of appraisal theories while circumventing shortcomings of previously used methods in appraisal studies. The results also indicate that the emotions were accounted for by specific configurations of appraisals over and above those accounted for by individual constituent appraisals.     

Teaching Engineering Ethics using BLOCKS Game

The aim of this study was to investigate the use of a newly developed design game called BLOCKS to stimulate awareness of ethical responsibilities amongst engineering students. The design game was played by seventeen teams of chemical engineering students, with each team having to arrange pieces of colored paper to produce two letters each. Before the end of the game, additional constraints were introduced to the teams such that they faced similar ambiguity in the technical facts that the engineers involved in the Challenger disaster had faced prior to the space shuttle launch. At this stage, the teams had to decide whether to continue with their original design or to develop alternative solutions. After the teams had made their decisions, a video of the Challenger explosion was shown followed by a post-game discussion. The students’ opinion on five Statements on ethics was tracked via a Five-Item Likert survey which was administered three times, before and after the ethical scenario was introduced, and after the video and post-game discussion. The results from this study indicated that the combination of the game and the real-life incident from the video had generally strengthened the students’ opinions of the Statements.     

广泛期小细胞肺癌一线化疗进展

小细胞肺癌(small cell lung cancer,SCLC)生长迅速,具有高度的侵袭性,就诊时多数患者已发生远处转移,对于广泛期小细胞肺癌,治疗仍以全身化疗为主,在过去30余年里,EP/CE方案作为标准一线化疗方案在治疗广泛期小细胞肺癌中取得了较高的缓解率,但多数患者在化疗停止6个月内疾病发生进展,2年的生存率不足5％,我们需要更加积极有效的一线化疗方案,本文综述了近10余年来广泛期小细胞肺癌的一线化疗进展.     

Asian culture in transition: is it related to reported parenting styles and transitivity of simple choices?

Does culture shape reported parenting styles and cognitive processes like transitive reasoning, of choosing A over B, B over C, and then A over C (transitivity)? Asian‐American, Caucasian‐American, and Indian university students differed significantly in transitivity and in reported parental styles. India participants were more intransitive and, contrary to traditional findings in the literature, reported their parents as more laissez‐faire, individualistic, and competitive than did Caucasian‐Americans. Recent technological and industrial advances in India likely explain some of these obtained differences. Predictions from Adlerian theory and work of Kurt Lewin, that parenting styles would relate to transitivity of choices, were indirectly supported. Stronger evidence was found that culture impacts both reported parental styles and transitivity of simple choices.     

决策的三参照点理论:从原理到应用

三参照点理论(Tri-Reference Point Theory,Wang,2008a; Wang& Johnson,2012)以底线、现状和目标为参照点,将决策结果空间划分为失败、损失、获益和成功4个功能区域.根据3个参照点的心理权重的排序:底线＞目标＞现状,该模型继而推导出跨越不同区域的以现状为分界的双S-型的价值函数,以及据此产生的对于跨越不同参照点的预期结果的偏好转换、和损失-获益及失败-成功的两种不对称性.总之,风险决策的基本任务在于,在使得达到目标的可能性最大化的同时使底线不保的可能性最小化.三参照点理论将统计学和金融学中的均值与方差(均差)分析与行为决策研究中的参照点效应有机地结合在一起;在面对不同的风险选项时,通过分析各个预期结果的均差分布与3个参照点之间的关系作出适应性的决策.本文介绍了三参照点理论的基本推论、运行原则、实证检验、以及它与期望效用理论和前景理论相比较的异同之处.同时我们也探讨了三参照点理论对实践中管理决策的指导意义和多重启示.     

辩证思维与辩证情绪的因果关系探究

辩证情绪是指个体对同一刺激同时体验到积极和消极情绪的一种心理状态.为探索辩证思维和辩证情绪的因果关系,在研究1中首先收集和筛选了诱发辩证情绪的视频;在研究2中,选取219个被试,先通过思维启动改变被试的辩证思维程度,然后考察辩证思维程度的改变对随后诱发辩证情绪强度的影响.结果发现,思维启动(辩证思维和线性思维)引起的辩证思维程度的差异显著,辩证情绪诱发效果显著,辩证思维在启动类型和辩证情绪之间的中介作用显著.这揭示了辩证思维程度的改变确实引起随后诱发的辩证情绪强度的变化,即辩证思维和辩证情绪存在因果关系.     

注意偏向训练对社交焦虑的干预：方法、效果与机制

社交焦虑障碍是最普遍且难于治疗的精神障碍之一。大量研究发现, 注意偏向训练可以有效缓解社交焦虑。研究者从自我报告、结构化评估、生理记录等方面考察发现, 接受了注意偏向训练的社交焦虑个体其注意偏向、生理唤醒和脑神经活动发生变化并且社交焦虑症状有所缓解。注意偏向训练对社交焦虑的干预机制可能是因为训练提升了个体对威胁性刺激的注意解除能力。今后的研究可以进一步明确注意偏向训练干预社交焦虑的效果与机制, 拓宽评估注意偏向训练效果的手段, 并探索其对社交焦虑干预的长期效果和对其它心理疾病的作用。     

初中生数学成绩、数学学业能力自我概念与数学学业情绪的关系

采用学业情绪问卷、数学学业自我概念问卷调查了370名初中学生,以探讨初中生数学学业情绪特点及其与数学成绩、数学学业能力自我概念间的关系。结果发现：（1）除积极高唤醒情绪外的其它数学学业情绪在性别上差异显著,除消极高唤醒外的其它情绪在年级上差异显著。（2）数学成绩通过数学学业能力自我概念间接预测四类数学学业情绪。结论是,初中男生数学积极情绪多于女生,女生数学消极情绪多于男生,积极情绪随年级下降,消极情绪随年级上升;初中生数学学业能力自我概念在数学成绩和数学学业情绪间起完全中介作用。