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551.
552.
药物成瘾会导致相关神经环路的结构和功能长期改变.大量新的研究证据表明,在DNA序列不变的情况下,药物成瘾可通过影响不同亚型DNA甲基转移酶(DNMTs)的表达,使脑内多个相关核团发生DNA甲基化以及基因表达的改变,进而导致神经元功能的可塑性变化.因此,DNA甲基化被视作导致成瘾行为长期存在的可能机制之一.结合近几年来的重要发现,本文将重点讨论相关脑区的DNA甲基化在成瘾行为发生发展过程中的作用,以及成瘾药物影响DNA甲基化水平的可能机制,并试图提出可深入的研究展望. 相似文献
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特征框架效应是指当分别以积极框架和消极框架来描述给定情景中的某一事物或事件的关键特征时,一般情况下人们更偏好以积极框架来描述其关键特征的事物或事件的现象.本研究通过2个实验验证了阈下特征框架效应的存在及其产生机制.实验一发现,阈下特征框架效应只在有时间压力下才会产生.实验二发现,被试对与框架类型一致的词汇判断的反应时比对与框架类型不一致的词汇判断的反应时更快,这在一定程度上说明特征框架效应的产生是因为框架激活了与框架一致性的信息,起到了语义启动的作用,从而导致被试判断任务的评定值偏向该框架类型. 相似文献
555.
合取谬误是一种常见的判断偏差,它指的是在不确定条件下,个体评估合取事件及其简单事件发生的概率时,对合取规则系统性偏离的一种现象.实验1 就认知需要类型对合取谬误的影响进行探讨,结果发现高认知需要的被试较不易表现出双重合取谬误和单合取谬误.实验2 探讨了警告类型对合取谬误的影响,结果发现无警告时个体最易表现出单合取谬误,其次是间接警告,最后是直接警告;此外,认知需要与警告类型的交互作用显著,高认知需要的被试在直接警告和间接警告时更少表现出双重合取谬误,在直接警告时更少表现出单合取谬误. 相似文献
556.
Yuhui Li Yanjun Guan Fuxi Wang Xiang Zhou Kun Guo Peng Jiang Zichuan Mo Yumeng Li Zheng Fang 《Journal of Vocational Behavior》2015
Based on career construction theory, the current research examined whether career adaptability mediates the relations of the personality traits (Five-Factor Model personality traits and behavioral inhibition and activation systems (BIS/BAS)) to career exploration behavior. Results from a survey in Chinese university students (N = 264) showed that career exploration correlated negatively with neuroticism, and positively with openness to experience, extroversion, agreeableness, conscientiousness and BAS. Results of regression analyses further showed that openness to experience, agreeableness, conscientiousness and BAS served as the strongest predictors for career exploration. In addition, career adaptability was shown to be a key mediator for the relationships between personality traits and career exploration behavior. Career concern and career curiosity were the more important dimensions in the mediation model. These findings advance current understandings on how different personality traits predict career exploration behavior. 相似文献
557.
Mechanochemical synthesis for studying the melting of metallic nanoparticles: a case study of copper
Mechanochemical synthesis is a promising method for studying the size-dependent melting of metals if the size of the resulting metallic nanoparticles can be tuned effectively. Here, with Cu as an example, we show that tuning of particle sizes can be accomplished by extending the milling time at a high milling speed and following annealing of the milled samples. With the so prepared samples, the melting point depression of Cu nanoparticles and its size dependence are successfully investigated. 相似文献
558.
Jie Sui Yang Sun Kaiping Peng Glyn W. Humphreys 《Attention, perception & psychophysics》2014,76(4):1176-1184
Attentional control over prepotent responses has previously been shown by manipulating the probability with which stimuli appear. Here, we examined whether prepotent responses to self-associated stimuli can be modulated by their frequency of occurrence. Participants were instructed to associate geometric shapes with the self, their mother, or a stranger before having to judge whether the sequential shape–label pairs matched or mismatched the instruction. The probability of the different shape–label pairs was varied. There was a robust advantage to self-related stimuli in all cases. Reducing the proportion of matched self pairs did not weaken performance with self-related stimuli, whereas reducing the frequency of either matched mother or stranger pairs hurt performance, relative to when the different match trials were equiprobable. In addition, while mother and stranger pairs jointly benefitted when they both occurred frequently, there were benefits only to self pairs when the frequency of self trials increased along with either mother or stranger trials. The results suggest that biases favoring self-related stimuli occur automatically, even when self-related stimuli have a low probability of occurrence, and that expectations to frequent, self-related stimuli operate in a relatively exclusive manner, minimizing biases to high-probability stimuli related to other people. In contrast, biases to high-familiarity stimuli (mother pairs) can be reduced when the items occur infrequently and they do not dominate expectations over other high-frequency stimuli. 相似文献
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The current study focused on contributions to the negative compatibility effect (NCE) from object-updating at the perceptual level and self-inhibition (i.e., automatic motor inhibition) at the response (motor) level. We hypothesized that contributions to the NCE from these two levels were moderated by the strength of stimulus and reaction (S–R) link: object-updating should have greater impact on the NCE with weak S–R links, but both object-updating and self-inhibition should impact on the NCE when the S–R links became strong. To test this hypothesis, in two experiments we used a novel type of stimuli and manipulated mask relevance (relevant versus irrelevant mask) and prime/target compatibility. Participants performed two tasks over three successive days. Results showed that under equivalent masking effectiveness between the two conditions of mask, a significant NCE was observed only in the relevant mask condition when the S–R links were weak, but both close to equal NCE sizes were observed in the two mask conditions when the S–R links were acquired through practice. The results indicated that perceptual and motor contributions to the NCE were moderated by the strength of S–R links, if the strength of the links was too weak to trigger the following inhibition, the NCE primarily originated from object-updating at the perceptual level; if the strength of the links was reinforced by practice, which exceeded the inhibitory threshold, the NCE originated from both object-updating and self-inhibition, but the latter was primarily responsible. 相似文献