Enriched housing reverses age-associated impairment of cognitive functions and tPA-dependent maturation of BDNF

Although tissue type plasminogen activator (tPA) and brain derived neurotrophic factor (BDNF) have been extensively described to influence brain outcomes in a number of disorders, their roles during physiological aging are poorly investigated. In the present study, we investigated whether maintenance of mice in different environmental conditions could influence age-associated changes in hippocampal tPA expression and BDNF maturation in relation with modifications of their cognitive performances. Our data indicate that maintenance in enriched housing led to a reversal of age-associated decrease in expression of hippocampal tPA. A subsequent increase in the level of mature BDNF and an improvement in emotional and spatial memories were observed. Taken together, these data suggest that the tPA–BDNF axis could play a critical role in the control of cognitive functions influenced both by the age and housing conditions.     

Increasing emotional competence improves psychological and physical well-being, social relationships, and employability

This study builds on earlier work showing that adult emotional competencies (EC) could be improved through a relatively brief training. In a set of 2 controlled experimental studies, the authors investigated whether developing EC could lead to improved emotional functioning; long-term personality changes; and important positive implications for physical, psychological, social, and work adjustment. Results of Study 1 showed that 18 hr of training with e-mail follow-up was sufficient to significantly improve emotion regulation, emotion understanding, and overall EC. These changes led in turn to long-term significant increases in extraversion and agreeableness as well as a decrease in neuroticism. Results of Study 2 showed that the development of EC brought about positive changes in psychological well-being, subjective health, quality of social relationships, and employability. The effect sizes were sufficiently large for the changes to be considered as meaningful in people's lives.     

Older adults' configural processing of faces: role of second-order information

Problems with face recognition are frequent in older adults. However, the mechanisms involved have only been partially discovered. In particular, it is unknown to what extent these problems may be related to changes in configural face processing. Here, we investigated the face inversion effect (FIE) together with the ability to detect modifications in the vertical or horizontal second-order relations between facial features. We used a same/different unfamiliar face discrimination task with 33 young and 33 older adults. The results showed dissociations in the performances of older versus younger adults. There was a lack of inversion effect during the recognition of original faces by older adults. However, for modified faces, older adults showed a pattern of performance similar to that of young participants, with preserved FIE for vertically modified faces and no detectable FIE for horizontally modified faces. Most importantly, the detection of vertical modifications was preserved in older relative to young adults whereas the detection of horizontal modifications was markedly diminished. We conclude that age has dissociable effects on configural face-encoding processes, with a relative preservation of vertical compared to horizontal second-order relations processing. These results help to understand some divergent results in the literature and may explain the spared familiar face identification abilities in the daily lives of older adults.     

“There is Nothing More…Than Dressing and Eating”: Li Zhi 李贄 and the Child-like Heart-Mind (Tongxin 童心)

This article examines the writings of the controversial 16th century thinker Li Zhi 李贄, also named (hao 號) Zhuowu 卓吾 (1527–1602), and argues that he articulates a coherent and compelling vision of a good life focused on the expression of genuine feelings distinctive to each individual. Through a study of literary texts and terms of art he refers to in his critical essay “On the Child-like Heart-mind” (Tongxin Shuo 童心說), as well as the metaphors and images he fleshes out throughout his writings, I characterize Li’s ethical vision and show that it is rooted in a particular loose and accommodating conception of human nature and centered on the simple and intuitive act of daily maintaining the birthright of our “child-like heart-mind.”     

Children's judgments about their own self‐knowledge: The role of disclosure to other

Previous research has suggested that children of 5/6 years fail to understand that they are the authority on their own self‐knowledge. That is, when asked questions like, ‘Who knows best when you are feeling tired?’, they tend to cite their mother rather than themselves. Here we report a study that, rather than asking about generalities (‘Who knows best what you are thinking?’), presented 5‐, 7‐ 9‐ and 11‐year‐children with hypothetical vignettes about specific circumstances in which they were described as either disclosing or not disclosing a specified state to their mother. Children were subsequently asked to judge who would best know the state. Over all age groups children were significantly more likely to identify themselves as authorities on their own self‐knowledge when states had not been disclosed to mother than when they had. However, in the case of disclosed states, young children (though not older ones) asserted that, ‘mum knows best’. These findings are interpreted as suggesting not that young children entirely fail to understand first person authority, but instead that they make the relatively sophisticated assumption that mothers' interpretive competence is greater than their own.     

Integral Bias in Naming of Phobia-related Words

Abstract

There is now considerable evidence that a person's cognitive processing is influenced by emotional factors. It is less clear, however, how this bias arises. Two hypotheses are distinguished and compared in the present study. The Inferred Bias hypothesis asserts that the cognitive effects of an emotion are not, in general, inherent consequences of that emotion, but instead arise from earlier experiences in which the particular patterns of emotional and Cognitive activity have tended to be associated. The Integral Bias hypothesis asserts, in contrast, that the cognitive effects of an emotion are in general a fundamental characteristic of that emotion. In order to compare these two hypotheses, the cognitive effects of a phobia in children were studied. An effect on the Stroop naming of spider-related words was detected in spider-phobic children as young as 6 or 7 years old. Furthermore, the magnitude of this effect did not differ significantly over the age range to 12 or 13 years old. These results can be interpreted as suggesting that in this case the cognitive effects of an emotional disturbance emerged relatively fully fledged at a young age, and as such arc consistent with the Integral Bias hypothesis of their origin.