Differences in feedback- and inhibition-related neural activity in adult ADHD

The objective of this study was to examine response inhibition- and feedback-related neural activity in adults with attention deficit hyperactivity disorder (ADHD) using event-related functional MRI. Sixteen male adults with ADHD and 13 healthy/normal controls participated in this study and performed a modified Go/NoGo task. Behaviourally, attention and inhibition problems in the ADHD group were observed; no feedback-related differences between the groups were detected. The neuroimaging data showed that the ADHD group displayed more activation in the inferior frontal gyrus and putamen during response inhibition. During feedback-related processes, the ADHD group displayed less activation in the inferior frontal/orbitofrontal cortex, hippocampus/nucleus accumbens, and caudate nucleus, but more activity in the inferior frontal gyrus. These results indicate that at least two distinguishable underlying brain networks related to response inhibition and feedback are altered in adults with ADHD.     

HIV, Cognition and Women

Although the incidence of HIV in the United States is higher among men compared to women, the global proportion of women versus men who are infected has been approximately 50% since the late 1990s. Women have been under-represented in neuropsychological studies of HIV. A small number of studies have reported a significantly higher prevalence of neurocognitive impairment among HIV+ women compared to HIV− controls regardless of symptom status and with or without an AIDS diagnosis. Impairment was most evident on psychomotor tasks. The risk of neuropsychological impairment was increased among HIV+ women not on antiretroviral therapy. Age and depressive symptoms also increase neurocognitive risk. New neurocognitive studies of ovarian steroid hormones, PTSD and other psychiatric conditions are critical for addressing potential female-specific aspects of HIV-Associated Neurocognitive Disorder. Such studies will also address questions regarding involvement of the hippocampus and verbal memory, which may be of particular significance among HIV+ women.

Long-term outcome of sex therapy

In a prospective investigation of the long-term outcome of 140 couples who had entered sex therapy 1–6 yrs earlier for a variety of sexual dysfunctions, successful follow-up, mostly by interview, was possible with at least one partner in 75% of cases. While recurrence of sexual difficulties was common, coping strategies were identified which often helped overcome relapses. Improvements in couples' general relationships resulting from treatment were usually sustained. Long-term outcome was excellent for vaginismus, good for erectile dysfunction, but often poor for premature ejaculation, and especially, for female impaired sexual interest. While the results of this study support the continued use of sex therapy for sexual dysfunction, they also emphasize the need for new therapeutic approaches for problems with poor outcome, especially female loss of sexual interest.     

Mood as input and perseverative worrying following the induction of discrete negative moods

Previous research has demonstrated that a combination of negative mood and rigorous "as many as can" stop rules can be used to help explain a range of perseverative psychopathologies such as pathological worrying, compulsive checking, and depressive rumination (known as the mood-as-input hypothesis). The aim of the present study was to extend this work and examine whether specific emotions of the same valence will have similar or differential effects on task perseveration. The study experimentally induced discrete moods and manipulated task stop rules in an analog population. Results showed that perseveration at a worry-based interview task conformed to standard mood-as-input predictions in which perseveration was significantly greater when an "as many as can" stop rule was paired with a negative mood or a "feel like continuing" stop rule was paired with a positively valenced mood. The pattern of results revealed no significant inherent differences in processing depending on the type of discrete negative mood being experienced. These findings support a view of mood-as-input effects where overall valency is the important factor in determining perseveration.     

The Myth of Closure

Therapies for grief and loss have traditionally focused on the work of grieving. The goal was to reach an endpoint, now popularly called closure. There are, however, many people who, through no fault of their own, find a loss so unclear that there can be no end to grief. They have not failed in the work of grieving, but rather have suffered ambiguous loss, a type of loss that is inherently open ended. Instead of closure, the therapeutic goal is to help people find meaning despite the lack of definitive information and finality. Hope lies in increasing a family's tolerance for ambiguity, but first, professionals must increase their own comfort with unanswered questions. In this article, the authors, one a poet, the other a family therapist and theorist, offer a unique blending of theory, reflection, and poetry to experientially deepen the process of self‐reflection about a kind of loss that defies closure.     

Canonical Extensions and Discrete Dualities for Finitely Generated Varieties of Lattice-based Algebras

The paper investigates completions in the context of finitely generated lattice-based varieties of algebras. In particular the structure of canonical extensions in such a variety ${\mathcal {A}}$ is explored, and the role of the natural extension in providing a realisation of the canonical extension is discussed. The completions considered are Boolean topological algebras with respect to the interval topology, and consequences of this feature for their structure are revealed. In addition, we call on recent results from duality theory to show that topological and discrete dualities for ${\mathcal {A}}$ exist in partnership.     

Subjective Wellbeing in China: A Review

We critically review studies of subjective wellbeing conducted in China by the International Wellbeing Group, and we evaluate the International Wellbeing Index (IWI), a new instrument they developed. Subjective wellbeing was positive and similar in studies across China, and conformed to the normative range. Its resilience (PWI = 61.2–67.1) mirrors survey findings conducted in Western countries, in agreement with Subjective Wellbeing Homeostasis. Reliability, validity and psychometric analyses support the utility of the IWI as a measure of subjective wellbeing. Our conclusions have implications for research and social development in China, discussed further in this review.     

Valence-specific laterality effects in vocal emotion: interactions with stimulus type, blocking and sex

Valence-specific laterality effects have been frequently obtained in facial emotion perception but not in vocal emotion perception. We report a dichotic listening study further examining whether valence-specific laterality effects generalise to vocal emotions. Based on previous literature, we tested whether valence-specific laterality effects were dependent on blocked presentation of the emotion conditions, on the naturalness of the emotional stimuli, or on listener sex. We presented happy and sad sentences, paired with neutral counterparts, dichotically in an emotion localisation task, with vocal stimuli being preceded by verbal labels indicating target emotions. The measure was accuracy. When stimuli of the same emotion were presented as a block, a valence-specific laterality effect was demonstrated, but only in original stimuli and not morphed stimuli. There was a separate interaction with listener sex. We interpret our findings as suggesting that the valence-specific laterality hypothesis is supported only in certain circumstances. We discuss modulating factors, and we consider whether the mechanisms underlying those factors may be attentional or experiential in nature.     

Cognitive neutralising strategies and their use across differing stressor types

Abstract

Three studies are described which investigate the kinds of strategies that individuals use to devalue the threatening meaning of a stressor (cognitive neutralising strategies, CNS). These studies identified seven factorially independent constructs corresponding to Downward Comparison, Positive Reappraisal, Cognitive Disengagement, Optimism, Faith in Social Support, Denial and Life Perspective. The use of CNS was highly correlated with the use of problem-focused coping strategies regardless of stressor type, but associated with the use of avoidance coping and emotion-focused coping only in the case of certain stressor types. The role of CNS in the coping process is discussed in the light of the present results.     

Book reviews

Eero Riikonen and Gregory Madan Smith (1997) Re-Imagining Therapy: Living Conversations and Relational Knowing, London: Sage, $14.99

Shulamit Ramon (1996) Mental Health in Europe: Ends, Beginnings and Rediscoveries, London: Mind, $12.99

Re:Public (eds) (1998) Planet Diana: Cultural Studies and Global Mourning, Kingswood, NSW: Research Centre in Intercommunal Studies, University of Western Sydney Nepean, pp. vii + 163, Aus$22

Lucy Yardley (ed.) (1997) Material Discourses of Health and Illness, London and New York: Routledge, pp. 256, $14.99 (pb), $45.00 (hb)

J.H. Berke, S. Pierides, A. Sabbadini and S. Schneider (1998) Even Paranoids Have Enemies, London: Routledge, $15.99

Hans W. Cohn (1997) Existential Thought and Therapeutic Practice, London: Sage, pp. 135, $11.99 (pb), $29.99 (hb)