Medication-assisted treatment research with criminal justice populations: challenges of implementation

Creating, implementing and evaluating substance abuse interventions, especially medication-assisted treatments, for prisoners, parolees, and probationers with histories of heroin addiction is an especially challenging endeavor because of the difficulty in coordinating and achieving cooperation among diverse criminal justice, substance abuse treatment, research, and social service agencies, each with its own priorities and agenda. In addition, there are special rules that must be followed when conducting research with criminal justice-involved populations, particularly prisoners. The following case studies will explore the authors' experience of over 10 years conducting pharmacotherapy research using methadone, buprenorphine, and naltrexone with criminal justice populations. The major obstacles and how they were overcome are presented. Finally, recommendations are provided with regard to implementing and conducting research with criminal justice populations. Copyright © 2011 John Wiley & Sons, Ltd.     

The effects of custodial vs non-custodial sanctions on reoffending: lessons from a systematic review

Based on a systematic review of some 23 (out of 300 originally located) studies, it is concluded that most studies show lower rates of re-offending following a non-custodial compared to a custodial sanction. However, this outcome may be biased because, in most quasi-experiments of this kind, subjects with the worst prospects of rehabilitation are likely to be sent to prison. In a meta-analysis limited to five randomised controlled trials and one natural experiment, it is concluded that custodial and non-custodial sanctions do not differ significantly in terms of re-offending. Lessons from this review include, in view of future evaluations, the need to increase randomised controlled trials, to use broader measures of re-offending and rehabilitation, to look at long-term effects, and to deal with possible Hawthorn effects. Equal rates of re-offending do not mean that or , but that criminal justice policies should not be based on the belief that short-term confinement will be damaging.     

Integrating haptic-tactile feedback into a video-capture-based virtual environment for rehabilitation.

Video-capture virtual reality (VR) systems are gaining popularity as intervention tools. To date, these platforms offer visual and audio feedback but do not provide haptic feedback. We contend that adding haptic feedback may enhance the quality of intervention for various theoretical and empirical reasons. This study aims to integrate haptic-tactile feedback into a video capture system (GX VR), which is currently applied for rehabilitation. The proposed multi-modal system can deliver audio-visual as well as vibrotactile feedback. The latter is provided via small vibratory discs attached to the patient's limbs. This paper describes the system, the guidelines of its design, and the ongoing usability study.     

Anomalous brain dominance and the immune system: Do left-handers have specific immunological patterns?

Geschwind and Behan (1982) and Geschwind and Galaburda (1985a, 1985b, 1985c) suggested a correlation between brain laterality and immune disorders. To test whether this hypothesis holds true not only for the frequency of immune diseases and circulating autoantibodies, but extends also to cellular immunity, we examined the association between handedness and markers of cellular immunity. Twenty-seven left-handed and 37 right-handed subjects were serologically screened for cellular parameters and 22 left-handed subjects were typed for human leukocyte antigen (HLA). When compared to the right-handers, the left-handed group showed a significant decrease in the inflammatory cell types CD3(+) T cells (total T cells), CD4(+) T cells (T-helper cells), and HLA-Dr (MHC-II, antigen-presenting cells) as well as in the CD19(+) cells (B cells) and CD16/CD57(+) cells (natural killer cells). We assume a relationship exists between cerebral hemispheric specialisation and the immune system not only for humoral but also for cellular immunity, and we discuss the role of the major histocompatibility complex in neurological and immunological development.     

MEMORY, AMNESIA, AND DISSOCIATIVE IDENTITY DISORDER

Abstract— Virtually all patients with dissociative identity (or multiple personality) disorder manifest interpersonality amnesia, whereby events experienced by a particular personality slate or identity are retrievable by that same identity but not by a different one Though considered a hallmark of dissociative identity disorder (DID), interpersonality amnesia has to date attracted little empirical attention. Further, the few studies on the topic typically include just 1 DID patient and a single index of retention. In contrast the current experiment involved 9 DID patients and several measures of either explicit or implicit memory Replicating and extending the single-case study of Nissen, Ross, Willingham, MacKenzie, and Schacter (1988), the present results revealed that implicit testing is a necessary but not a sufficient condition for demonstrating transfer of information from one identity to another Specifically, whereas priming in word-stem completion occurred only if the same personality state performed at both study and at test, priming in picture-fragment completion was as robust between different identities as it was within the same identity Discussion focuses on prospects for future research aimed at understanding the nature and scope of interpersonality amnesia.     

The onset time delaying effect: smokers vs non-smokers place the adverse consequences of smoking further in the future

Despite all the information about the risks, many people still smoke. Several studies investigated risk perceptions in smokers. The adequate perceptions of the risks from smoking is particularly important and this study investigated the risk perception of young smokers vs non-smokers by a new time-estimation task in which we required participants (smokers and non-smokers) to estimate the onset time of smoking-related conditions in an average young smoker. The findings supported our main hypothesis that smokers, compared to non-smokers, postponed the onset of both mild and severe smoking-related conditions. The results also revealed that the onset time estimates for mild conditions given by both smokers and non-smokers were associated with their self-perceptions of risk and level of fear of developing smoking-related conditions. The findings cast light on smokers’ distorted temporal perception of the health-damaging consequences of smoking. Implications for the adequacy of risk perception in smokers are discussed.     

Bidirectional links in the network of multiplication facts

In three experiments, we tested the hypothesis that activation of multiplication operand nodes (e.g., 3 and 8) can occur through presentation of their product (e.g., 24). In Experiments 1 and 2 we found activation of the operands when the product was presented as a cue in a number-matching task. In Experiment 3, activation also occurred in a parity-matching task, where the product (24) was not relevant to the parity matching on its operands (3 and 8). We concluded that bidirectional links exist among the operands and their product for multiplication problems and these links can be activated in a purely stimulus-driven manner. We suggest this may constitute the basis for the solution of simple divisions by mediation through the complementary multiplication facts.     

Number magnitude orients attention, but not against one’s will

Recent evidence has shown that uninformative numbers can trigger attention shifts congruent with the spatial representation of number magnitude (Fischer, Castel, Dodd, & Pratt, 2003). In the present study, three spatial-cuing experiments whose aim was to qualify the automaticity of this numbermediated orienting are described. Experiment 1 replicated the phenomenon, showing that uninformative numbers can evoke orienting in a simple detection task. In Experiment 2, target location was random, but the participants were encouraged to shift attention to the left in response to large numbers and to the right in response to small numbers. No evidence for strong automaticity was observed, since the participants’ performance was better when left-side targets were preceded by large numbers than when they were preceded by small numbers and vice versa. Experiment 3 corroborated this pattern by comparing gaze- and number-mediated cuing under conditions of real counterpredictiveness. The results indicate that unlike gaze-driven orienting, number-mediated orienting is not obligatory.     

Automatic spatial coding of perceived gaze direction is revealed by the Simon effect

In a typical Simon task, the (irrelevant) spatial position of the stimulus interferes with the processing of the salient characteristic (e.g., color). We used the Simon effect to investigate the automatic processing of gaze cues. We show that a simple drawing of schematic eyes automatically generates a spatially defined code of gaze direction. Although completely irrelevant to the task, direction of gaze influenced reaction times in a spatially selective two-choice discrimination based on eye color. Moreover, in one experiment employing an orthogonal manipulation of stimulus position and gaze direction, we found that coding of gaze direction is independent of stimulus spatial coding. Our finding of a “gazedirection Simon effect” is congruent with the hypothesis that gaze direction is coded by a specialized mechanism.     

The SNARC effect: an instance of the Simon effect?

Our aim was to investigate the relations between the Spatial-Numerical Association of Response Codes (SNARC) effect and the Simon effect. In Experiment 1 participants were required to make a parity judgment to numbers from 1 to 9 (without 5), by pressing a left or a right key. The numbers were presented to either the left or right side of fixation. Results showed the Simon effect (left-side stimuli were responded to faster with the left hand than with the right hand whereas right-side stimuli were responded to faster with the right hand), and the SNARC effect (smaller numbers were responded to faster with the left hand than with the right hand, whereas larger numbers were responded to faster with the right hand). No interaction was found between the Simon and SNARC effects, suggesting that they combine additively. In Experiment 2 the temporal distance between formation of the task-relevant non-spatial stimulus code and the task-irrelevant stimulus spatial code was increased. As in Experiment 1, results showed the presence of the Simon and SNARC effects but no interaction between them. Moreover, we found a regular Simon effect for faster RTs, and a reversed Simon effect for longer RTs. In contrast, the SNARC effect did not vary as a function of RT. Taken together, the results of the two experiments show that the SNARC effect does not simply constitute a variant of the Simon effect. This is considered to be evidence that number representation and space representation rest on different neural (likely parietal) circuits.