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21.
Horse-race model simulations of the stop-signal procedure   总被引:18,自引:0,他引:18  
In the stop-signal paradigm, subjects perform a standard two-choice reaction task in which, occasionally and unpredictably, a stop-signal is presented requiring the inhibition of the response to the choice signal. The stop-signal paradigm has been successfully applied to assess the ability to inhibit under a wide range of experimental conditions and in various populations. The current study presents a set of evidence-based guidelines for using the stop-signal paradigm. The evidence was derived from a series of simulations aimed at (a) examining the effects of experimental design features on inhibition indices, and (b) testing the assumptions of the horse-race model that underlies the stop-signal paradigm. The simulations indicate that, under most conditions, the latency, but not variability, of response inhibition can be reliably estimated.  相似文献   
22.
Inhibitory attentional control in patients with frontal lobe damage   总被引:3,自引:0,他引:3  
The performance of a group of frontal lobe lesion and a group of frontal lobe dementia patients was compared with the performance of their respective matched normal control groups on two tests of inhibitory attentional control-the stop-signal reaction time task and a negative priming task. Both patient groups responded significantly slower than their respective normal control groups, but they showed only marginally significant selective impairments on the measures of inhibition. The data suggest that the specific inhibitory processes evaluated by these two tests are, in general, spared in patients with focal frontal lobe lesions or frontal lobe degeneration.  相似文献   
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The reliability of subjects' judgments of the groups present in dot patterns and the sensitivity of those judgments to stimulus transformation were assessed. The subjects indicated the groups that they saw within random dot patterns, and each judgment was compared with those of other subjects and with their own judgments for related presentations. Within subjects, each pattern appeared in an initial presentation, an identical repetition, and a transformed state (a rotation or a change in scale). Within-subjects judgments were more reliable than between-subjects judgments. An interpretation of within-subjects results was made in relation to predictions made by a formal algorithm of grouping by proximity (the CODE algorithm), which assumes that grouping by proximity is invariant over transformations such as rotations or changes in scale. A slight cost to transforming the patterns was found. The implications for CODE and for using grouping judgments as data are discussed.  相似文献   
25.
Anger is a significant human emotion with far‐reaching implications for individuals and relationships. We propose a transactional model of anger that highlights its relational relevance and potentially positive function, in addition to problematic malformations. By evolutionary design, physical, self‐concept, or attachment threats all similarly trigger diffuse physiological arousal, psychologically experienced as anger‐emotion. Anger is first a signaling and motivational system. Anger is then formed to affirming, productive use or malformed to destructive ends. A functional, prosocial approach to anger organizes it for protective and corrective personal and relational adaptation. In our model, threat perception interacts with a person's view of self in relation to other to produce helpful or harmful anger. Inflated or collapsed views of self in relation to other produce distinct manifestations of destructive anger that are harmful to self, other, and relationship. Conversely, a balanced view of self in relation to other promotes constructive anger and catalyzes self, other, and relationship healing. Clinical use of the model to shape healing personal and relational contact with anger is explored.  相似文献   
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Patterson SY  Smith V  Mirenda P 《Autism》2012,16(5):498-522
Aim: The purpose of this systematic review was to examine research utilizing single subject research designs (SSRD) to explore the effectiveness of interventions designed to increase parents' ability to support communication and social development in children with autism spectrum disorders (ASDs). Method: Included studies were systematically assessed for methodological quality (Logan et al., 2008; Smith et al., 2007) and intervention effects. Data examining participant characteristics, study methodology, outcomes, and analysis were systematically extracted. Results: Eleven SSRD parent-training intervention studies examining 44 participants with ASD were included. Overall, the studies were of moderate quality and reported increases in parent skills and child language and communication outcomes. Interpretation: The results supported by improvement rate difference (IRD) analysis indicated several interventions demonstrated positive effects for both parent and child outcomes. However, limited generalization and follow-up data suggested only one intervention demonstrated parents' accurate and ongoing intervention implementation beyond training.  相似文献   
28.
About 10 % of infertile/subfertile women are diagnosed with diminished ovarian reserve (DOR), of which?<?5 % will become pregnant spontaneously. Fragile X (FMR1) genetic testing may provide a reason for her early ovarian aging and/or have reproductive implications. Seven women with DOR (genetic study subset) and the male partners of six of these women were separately interviewed about the experience of being asked to undergo this unanticipated genetic test. Three interviews were conducted (before, within 1 week after, and 3 months after learning the test results). None of the participants carried the FMR1 premutation (largest FMR1 allele 27–50 CGG repeats). For women, their pregnancy-seeking journey was long and exhausting. Women understood the reproductive implications of carrying the FMR1 premutation, and hoped for a negative result. Being offered a genetic test caused women to pause and re-think their future reproductive plans. Husbands viewed the infertility journey as filled with unknowns, of which the genetic test results would be one more puzzle piece. The expense of fertility testing/treatment was mentioned by both spouses, though more notably by husbands. The introduction of a possible genetic cause of infertility, with additional potential health consequences for future biological children, caused women to re-think their quest for pregnancy. In contrast, the genetic test was viewed as an additional source of information for their husbands as opposed to raising concern regarding potential reproductive ramifications.  相似文献   
29.
An unresolved issue in the task-switching literature is whether preparatory reconfiguration occurs before a change of task. In this study, we used event-related potentials (ERPs) to determine whether preparatory reconfiguration occurs during two different task-switching procedures: voluntary and cued task switching. We focused on two ERP components that index different cognitive operations. The contingent negative variation (CNV) is a sensitive measure of a participant’s preparedness to use a specific stimulus–response mapping. In contrast, the P3 indexes memory updating. We found a pronounced modulation of the CNV before voluntary task switches, but not before cued task switches. Instead, cued task switches were preceded by a larger P3, as compared with task repetitions. Our findings suggest that task set reconfiguration is carried out prior to voluntary task switches, whereas memory processes dominate cued task switches.  相似文献   
30.
When we plan sequences of actions, we must hold some elements of the sequence in working memory (WM) while we execute others. Research shows that execution of an action can be delayed if it partly overlaps (vs. does not overlap) with another action plan maintained in WM (partial repetition cost). However, it is not known whether all features of the action maintained in WM interfere equally with current actions. Most serial models of memory and action assume that interference will be equal, because all action features in the sequence should be activated to an equal degree in parallel; others assume that action features earlier in the sequence will interfere more than those later in the sequence, because earlier features will be more active. Using a partial repetition paradigm, this study examined whether serial position of action features in action sequences maintained in WM have an influence on current actions. Two stimulus events occurred in a sequence, and participants planned and maintained an action sequence to the first event (action A) in WM while executing a speeded response to the second event (action B). Results showed delayed execution of action B when it matched the first feature in the action A sequence (partial repetition cost), but not when it matched the last feature. These findings suggest that serial order is represented in the action plan prior to response execution, consistent with models that assume that serial order is represented by a primacy gradient of parallel feature activation prior to action execution.  相似文献   
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