Executive functions,impulsivity, and inhibitory control in adolescents: A structural equation model

Background. Adolescence represents a critical period for brain development, addressed by neurodevelopmental models to frontal, subcortical-limbic, and striatal activation, a pattern associated with rise of impulsivity and deficits in inhibitory control. The present study aimed at studying the association between self-report measures of impulsivity and inhibitory control with executive function in adolescents, employing structural equation modeling. Method. Tests were administered to 434 high school students. Acting without thinking was measured through the Barratt Impulsiveness Scale and the Dickman Impulsivity Inventory, reward sensitivity through the Behavioral Activation System, and sensation seeking through the Zuckerman–Kuhlman–Aluja Personali- ty Questionnaire. Inhibitory control was assessed through the Behavioral Inhibition System. The performance at the Wisconsin Card Sorting Task indicated executive function. Three models were specified using Sample Covariance Matrix, and the estimated parameters using Maximum Likelihood. Results. In the final model, impulsivity and inhibitory control predicted executive function, but sensation seeking did not. The fit of the model to data was excellent. Conclusions. The hypothesis that inhibitory control and impulsivity are predictors of executive function was supported. Our results appear informative of the validity of self-report measures to examine the relation between impulsivity traits rather than others to regulatory function of cognition and behavior.     

The effect of experience and of dots’ density and duration on the detection of coherent motion in dogs

Knowledge about the mechanisms underlying canine vision is far from being exhaustive, especially that concerning post-retinal elaboration. One aspect that has received little attention is motion perception, and in spite of the common belief that dogs are extremely apt at detecting moving stimuli, there is no scientific support for such an assumption. In fact, we recently showed that dogs have higher thresholds than humans for coherent motion detection (Kanizsar et al. in Sci Rep UK 7:11259, 2017). This term refers to the ability of the visual system to perceive several units moving in the same direction, as one coherently moving global unit. Coherent motion perception is commonly investigated using random dot displays, containing variable proportions of coherently moving dots. Here, we investigated the relative contribution of local and global integration mechanisms for coherent motion perception, and changes in detection thresholds as a result of repeated exposure to the experimental stimuli. Dogs who had been involved in the previous study were given a conditioned discrimination task, in which we systematically manipulated dot density and duration and, eventually, re-assessed our subjects’ threshold after extensive exposure to the stimuli. Decreasing dot duration impacted on dogs’ accuracy in detecting coherent motion only at very low duration values, revealing the efficacy of local integration mechanisms. Density impacted on dogs’ accuracy in a linear fashion, indicating less efficient global integration. There was limited evidence of improvement in the re-assessment but, with an average threshold at re-assessment of 29%, dogs’ ability to detect coherent motion remains much poorer than that of humans.     

On Argumentation Logic and Propositional Logic

This paper studies the relationship between Argumentation Logic (AL), a recently defined logic based on the study of argumentation in AI, and classical Propositional Logic (PL). In particular, it shows that AL and PL are logically equivalent in that they have the same entailment relation from any given classically consistent theory. This equivalence follows from a correspondence between the non-acceptability of (arguments for) sentences in AL and Natural Deduction (ND) proofs of the complement of these sentences. The proof of this equivalence uses a restricted form of ND proofs, where hypotheses in the application of the Reductio of Absurdum inference rule are required to be “relevant” to the absurdity derived in the rule. The paper also discusses how the argumentative re-interpretation of PL could help control the application of ex-falso quodlibet in the presence of inconsistencies.     

rTMS for PTSD: induced merciful oblivion or elimination of abnormal hypermnesia?

Neuroimaging studies and experimental data suggest that symptoms of posttraumatic stress disorder (PTSD) are associated with dysfunctions of neural circuits linking prefrontal cortex and the limbic system that have a role in autobiographic episodic memory. High-frequency repetitive transcranial magnetic stimulation (rTMS) of the right dorsolateral prefrontal cortex (DLPFC) has been suggested to be beneficial to patients with PTSD, transiently alleviating re-experiencing as well as avoidance reactions and associated anxiety symptoms. In healthy humans, converging evidence suggests that rTMS of the right DLPFC interferes with episodic memory retrieval. Hence, we hypothesize that daily applications of rTMS in PTSD patients may reduce access to the set of autobiographical stored events, that, if re-experienced, may cause the overt PTSD symptoms.     

The validity of the hospital anxiety and depression scale and the geriatric depression scale in Parkinson's disease

We assessed the concurrent validity of the Hospital Anxiety and Depression Scale (HADS) and the Geriatric Depression Scale (GDS) against the Hamilton Rating Scale for Depression (Ham-D) in patients with Parkinson's disease (PD). Forty-six non-demented PD patients were assessed by a neurologist on the Ham-D. Patients also completed four mood rating scales: the HADS, the GDS, the VAS and the Face Scale. For the HADS and the GDS, Receiver Operating Characteristics (ROC) curves were obtained and the positive and negative predictive values (PPV, NPV) were calculated for different cut-off scores. Maximum discrimination between depressed and non-depressed PD patients was reached at a cut-off score of 10/11 for both the HADS and the GDS. At the same cut-off score of 10/11 for both the HADS and the GDS, the high sensitivity and NPV make these scales appropriate screening instruments for depression in PD. A high specificity and PPV, which is necessary for a diagnostic test, was reached at a cut-off score of 12/13 for the GDS and at a cut-off score of 11/12 for the HADS. The results indicate the validity of using the HADS and the GDS to screen for depressive symptoms and to diagnose depressive illness in PD.     

Kierkegaard’s Regulative Sacrifice: A Post-Kantian Reading of Fear and Trembling

Abstract

The present paper suggests to consider Kierkegaard’s use of Abraham’s story in Fear and Trembling in regulative terms, that is, to consider it as a model – not for our moral behaviour but rather for our religious behaviour. To do so, I first rely on recent literature to argue that Kierkegaard should be regarded as a distinctively post-Kantian philosopher: namely, a philosopher who goes beyond Kant in a way that is nevertheless true to the spirit of Kant’s original critical philosophy. Then, I present a post-Kantian reading of Fear and Trembling, focusing on the problematic implications that result from comparing this text with Hegel’s theory of recognition. Finally, I submit that sacrifice in Fear and Trembling is a regulative notion in a Kantian sense. This interpretation addresses some of the most problematic aspects of the text. I conclude that the regulativity of sacrifice may be regarded as an important and perhaps an essential component of Kierkegaard’s overall philosophical strategy.     

Kant’s sacrificial turns

This paper addresses the role of the notion of sacrifice in Kant’s theoretical philosophy, practical philosophy, and in his account of religion. First, I argue that kenotic sacrifice, or sacrifice as ‘withdrawal’, plays a hidden and yet important role in the development of Kant’s transcendental philosophy. Second, I focus on Kant’s practical philosophy, arguing that the notion of sacrifice that is both implied and explicitly analyzed by Kant is mainly suppressive sacrifice. However, Kant’s account is fundamentally ambiguous, as sometimes the kenotic meaning of sacrifice seems to resurface, especially in the context of Kant’s discussion of the happiness of others as an end in itself. Because religious notions are regarded by Kant as necessary transitional forms (Darstellungen) to be used to make moral ideas applicable to the world, I then scrutinize Kant’s view of sacrifice as an improper symbol, and I analyze Kant’s arguments for such a dismissal and discuss the subject matter in recent literature. Finally, I examine the role of sacrifice in Kant’s account of Christ as the prototype of pure moral disposition. I conclude by arguing that Kant indeed grasped the importance of including kenotic dynamics in practical philosophy but was somehow unable or unwilling to integrate it into the formal grounding of his ethics. This tension, however, effectively provides an entry point for features that can be found in the post-Kantians.