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71.
72.
Wang Z Pan Y Li W Jiang H Chatzimanolis L Chang J Gong Z Liu L 《Learning & memory (Cold Spring Harbor, N.Y.)》2008,15(3):133-142
The role of the foraging (for) gene, which encodes a cyclic guanosine-3',5'-monophosphate (cGMP)-dependent protein kinase (PKG), in food-search behavior in Drosophila has been intensively studied. However, its functions in other complex behaviors have not been well-characterized. Here, we show experimentally in Drosophila that the for gene is required in the operant visual learning paradigm. Visual pattern memory was normal in a natural variant rover (for(R)) but was impaired in another natural variant sitter (for(S)), which has a lower PKG level. Memory defects in for(S) flies could be rescued by either constitutive or adult-limited expression of for in the fan-shaped body. Interestingly, we showed that such rescue also occurred when for was expressed in the ellipsoid body. Additionally, expression of for in the fifth layer of the fan-shaped body restored sufficient memory for the pattern parameter "elevation" but not for "contour orientation," whereas expression of for in the ellipsoid body restored sufficient memory for both parameters. Our study defines a Drosophila model for further understanding the role of cGMP-PKG signaling in associative learning/memory and the neural circuit underlying this for-dependent visual pattern memory. 相似文献
73.
74.
从卡介苗成功治疗膀胱癌论肿瘤的免疫治疗 总被引:3,自引:0,他引:3
卡介苗(BCG)膀胱内灌注是治疗浅表性膀胱癌一种最有效的方法。通过对治疗后的监测发现,卡介苗灌注后可引发肿瘤部位显著的固有免疫和适应性免疫细胞反应,体内大多数的抗肿瘤免疫效应细胞参与这一反应过程。这一结果表明,有效的肿瘤免疫治疗必须由固有免疫和适应性免疫细胞协同作用才能完成。 相似文献
75.
76.
策略型学习者认知心理结构及其运行机制 总被引:2,自引:0,他引:2
高效率学习是现代社会发展的需要,也是适应信息量急增的社会变革需要的必然选择。从教育心理学的视角研究策略型学习者,对其高效率学习心理,特别是高效率学习认知心理结构及其运行机制进行研究,有助于教育理论与实践工作者准确把握这类特殊教育对象的心理特点与规律,为开展策略型学习者教育提供了心理学依据。 相似文献
77.
78.
供应链伙伴间的信任、承诺对合作绩效的影响 总被引:18,自引:0,他引:18
本文通过问卷调查的方式探讨供应链伙伴间的信任、关系承诺对合作绩效的影响。研究结果显示组织信任、个人信任与合作绩效存在正相关关系,组织信任通过关系承诺对合作绩效的间接影响明显高于其直接影响,个人信任通过关系承诺对合作绩效的间接影响明显不及其直接影响。 相似文献
79.
The literature on policy transfer between countries and organization has seen rapid growth. Whether framed in terms of policy
transfer, institutional transplantation, imitation and emulation or copying policy models and ideas, a sizeable number of
determinants for success have been identified to understand why such conceptual or institutional transfers grow out to become
successes or failures in their countries or organizations of adoption. What is much less common is to describe such a process
through the lens of participants inside this transfer. This paper is an attempt to do just that. It will tell the story of
the higher-educational concept of Technology, Policy and Management from Delft University of Technology in the Netherlands
to Harbin Institute of Technology in China, studied by means of participatory observation. The keys and clues for successful
transplantation from the literature will subsequently be compared with the experiences from this case, and additional lessons,
some of which are specific to Western-Chinese mutual learning, are formulated.
Martin de Jong is associate professor of policy, organization and management at the Faculty of Technology, Policy and Management
of Delft University of Technology, the Netherlands. He publishes and lectures mainly on subjects of cross-national policy
transfer, cross-cultural management and transport infrastructure policy. He is also responsible for the international master
program Engineering and Policy Analysis, for which he has helped to set up a Chinese counterpart with the same name.
Xi Bao is professor of public management and real estate management at the School of Management and the National Centre of
Technology, Policy and Management of Harbin Institute of Technology, People’s Republic of China. He is also a co-director
of the National Centre of TPM in China and lectures and publishes mainly on real estate management and infrastructure policy. 相似文献
80.
术前谈话与患者的知情同意权 总被引:3,自引:2,他引:1
告知说明义务是医师的法定义务,知情同意权是患者的法定权利,术前谈话是外科医师履行告知说明义务和手术患者实现知情同意权的共同方式。外科医师应深入理解患者的知情同意权,合理履行告知说明义务,临床实践中做到告知说明内容充分,变更手术重新告知说明,避免使用穷尽式列举,确定签字人身份合法且具有完全民事行为能力。 相似文献