Neuropsychological Functioning in Children with Medium Chain Acyl Coenzyme A Dehydrogenase Deficiency (MCADD): The Impact of Early Diagnosis and Screening on Outcome

Children with medium chain acyl coenzyme A dehydrogenase deficiency (MCADD) have been reported to be at high risk for neurocognitive deficits. However this has not been systematically studied and little is known about the exact nature of neuropsychological sequelae or of the impact of early diagnosis and screening on outcome. We examined cognitive and adaptive outcome in children with MCADD (N?=?38, age range: 2 years, 2 months – 10 years, 3 months) diagnosed either through a newborn screening program (tandem mass spectrometry/MSMS) or upon clinical presentation. There was no evidence of overall intellectual impairment in either groups but there was some suggestion of poorer verbal and specific executive functioning (i.e., planning) abilities in the unscreened cohorts. Adaptive functioning was relatively intact with the exception of reduced Daily Living Skills in both our screened and unscreened groups. Early diagnosis and greater number of hospitalizations were related to higher verbal, communication, and socialization skills. Overall, our results highlight the importance of early diagnosis and management for children with MCADD.     

Personal Construction of Family Relationships: The Relation of Commonality and Sociality to Family Satisfaction for Parents and Adolescents

This study tested the hypothesis that family members showing greater commonality (similarity) and sociality (predictive accuracy) in their construing of family relationships would display greater satisfaction with those relationships than would individuals in families whose relational construing was more discrepant and unpredictable. Forty-seven family triads participated in the study, including a mother, father, and adolescent from each family. Measures of commonality and sociality in the construction of family relationships derived from a family relationships grid were compared to measures of family structure, including the Family Cohesion and Adaptability Evaluation Scale (FACES-II) (Olson, Portner, & Bell, 1982) and the Parent-Adolescent Communication Scale (PACS) (Barnes & Olson, 1982). The findings suggest that members' perceptions of the family as emotionally close, flexible, and communicative may not represent independent aspects of the family structure, at least within the present nonclinical sample. Comparison of the family relationship grids with the FACES-H and PACS demonstrated that commonality and sociality among family members was highly related to mothers' and adolescents' family satisfaction, but was much less predictive of that of the father.     

Fitting the world to constructs: The role of activity in meaning making

Abstract

The authors underscore that construing is not simply a matter of passively anticipating events. Meaning making is understood more fully as a dialectic involving anticipation as well as participation, accommodation as well as assimilation. Factors that may obscure this more active view of the meaning-making process are discussed, and illustrations of the role of activity in construing are presented.     

Counselling asylum seekers and refugees: a study of Kurds in early and later stages of exile

This study explores the experience of asylum seekers and refugees in early and later phases of exile. Twenty-five Kurds (mainly asylum seekers) were interviewed in Greece in early phases of exile and twenty Kurds (mainly refugees) in later phases of exile in the UK. Refugee camps in Greece and community centres in London were the main locations for these interviews. Representatives from eight support organizations were also interviewed in each country. The multidimensional aspects of being a refugee are discussed, including models of formulating the experience, PTSD and the cross-cultural context. Key findings of the study include the desperate need among the asylum seekers and refugees, in the early phases, to have the story of their traumatic journey to Greece witnessed and validated by an outsider; the differing experiences of men and women; a change in identity over time; and considerable fear, which was evident in early and later phases. Moreover, all the support organizations expressed pronounced frustration but responded to it in different ways. Those organizations with supervision and support groups in place demonstrated more insight into their interactions with asylum seekers and refugees. Counselling approaches are evaluated with reference to the asylum seekers' and refugees' needs, and the desirability of adequate support for those with a counselling role is highlighted.     

Teaching with Complicating Views: Beyond the Survey,Behind the Pro and Con

In this article I propose a method of selecting and assigning readings in the religious studies or theology classroom, such that these readings complicate one another, rather than standing in opposition or as simple alternatives. Such a strategy emulates key pedagogical insights of twelfth‐century sentence collection, an activity at the very heart of the earliest universities in Europe. It also draws support from the theories of intellectual development advanced by William G. Perry, Jr. and the Women's Ways of Knowing Collaborative. Both precedents suggest a principle of “complicating views” that can be flexibly employed in a variety of ways and diverse pedagogical contexts, as illustrated by examples from several classes. Such strategies aim to avoid reinforcing intellectual patterns of dualism or undifferentiated relativism; instead, they attempt to promote students' ability to integrate discordant voices and to appreciate diverse points of view, while also staking their own claims relative to them.     

Pushing the limits of task difficulty for the right and left hands in manual aiming

The effects of task difficulty on the performance of the two hands in right-handers were examined in a manual-aiming paradigm. In order to examine both simple and complex tasks, movement amplitude, cursor size, and target size were manipulated, resulting in eight different indices of difficulty (as defined by Fitts' Law). Kinematic parameters examined included reaction time, movement time, time to and time after peak velocity, peak velocity, and resultant accuracy. Analysis revealed no differential effects of task difficulty on the overall movement times of the two hands. These results are discussed in light of current theories of manual asymmetries.     

Natural Doubts: Williams's Diagnosis Of Scepticism

Michael Williams believes that scepticism about the externalworld seems compelling only because the considerations that underpin it are thoughtto be ``mere platitudes' about e.g., the nature and source of human knowledge, and hence,that if it shown through a ``theoretical diagnosis' that it does not rest upon suchplatitudes, but contentious theoretical considerations that we are no means bound toaccept, we can simply dismiss the absurd sceptical conclusion. Williams argues thatscepticism does presuppose two extremely contentious doctrines, however, he admits thatif these doctrines are themselves motivated by ``platitudes' then scepticism follows. Iaddress Williams's arguments for thinking scepticism must presuppose these doctrines,and argue that he overlooks a way that they can be seen as motivated by mere platitudes.Thus, I conclude that William's novel rejection of scepticism fails.     

Visual agnosia and prosopagnosia in childhood: a prospective case study.

Selective impairments in visual processing are well documented in adults but rarely reported in children. The few childhood cases reported are mostly retrospective accounts with little attention paid to developmental, assessment or management issues. We report a prospective case study of a boy with prosopagnosia and visual processing deficits of presumed developmental origin. At the age of 4 years, AL presented with a range of cognitive and visual recognition deficits. Subsequent assessments revealed an evolving pattern in visual recognition and dissociations between developing skills. At the age of 7 AL has impairments in early perceptual analysis, visual organisation and in complex visual processing. Although he can identify facial features and match faces he is unable to recognise familiar faces. His reading and spelling are developing normally. The nature of his deficits and his progress are discussed within a cognitive neuropsychological framework.     

Psychoeducational Interventions with Pediatric Cancer Patients: Part II. Effects of Information and Skills Training on Health-Related Outcomes

In Part I of this paper, we described a model that was used as a framework for reviewing studies of psychoeducational interventions intended to influence illness- and treatment-related behaviors and attitudes in pediatric cancer patients. In Part II, we distinguish between interventions that attempt to influence patients' behaviors just by providing information and interventions that specifically teach skills related to the behaviors they are trying to change. Many types of psychoeducational interventions appear to be effective and those that are training-based generally appear more effective than those that are information-based. Training-based interventions may face a barrier to wide adoption because they are resource-costly, but the development of digital-based training interventions may potentially overcome this barrier.     

Psychometric Properties and Norms of the Family Needs Scale

We studied 205 low-income families, using the Family Needs Scale (FNS). Factor analysis of the FNS data resulted on a 7-factor solution with high internal consistency within the various subscales. We provide normative scores based on the factor structure of the FNS. A total of 53 parents completed the FNS on two occasions with an average of four weeks between these two ratings. In general, the test-retest reliabilities were low to moderate. A total of 61 pairs of parents independently rated their families with the FNS. Again, agreement between raters was low to moderate. Several factors that may have detracted from better test-retest and interrater reliability were identified. Our data point to the need for more psychometric studies with the FNS.