Neuropsychological Functioning in Children with Medium Chain Acyl Coenzyme A Dehydrogenase Deficiency (MCADD): The Impact of Early Diagnosis and Screening on Outcome

Children with medium chain acyl coenzyme A dehydrogenase deficiency (MCADD) have been reported to be at high risk for neurocognitive deficits. However this has not been systematically studied and little is known about the exact nature of neuropsychological sequelae or of the impact of early diagnosis and screening on outcome. We examined cognitive and adaptive outcome in children with MCADD (N?=?38, age range: 2 years, 2 months – 10 years, 3 months) diagnosed either through a newborn screening program (tandem mass spectrometry/MSMS) or upon clinical presentation. There was no evidence of overall intellectual impairment in either groups but there was some suggestion of poorer verbal and specific executive functioning (i.e., planning) abilities in the unscreened cohorts. Adaptive functioning was relatively intact with the exception of reduced Daily Living Skills in both our screened and unscreened groups. Early diagnosis and greater number of hospitalizations were related to higher verbal, communication, and socialization skills. Overall, our results highlight the importance of early diagnosis and management for children with MCADD.     

Individuals with Autism can Categorize Facial Expressions

The ability of high-functioning individuals with autism to perceive facial expressions categorically was studied using eight facial expression continua created via morphing software. Participants completed a delayed matching task and an identification task. Like undergraduate male participants (N = 12), performance on the identification task for participants with autism (N = 15) was predicted by performance on the delayed matching task for the angry-afraid, happy-sad, and happy-surprised continua. This result indicates a clear category boundary and suggests that individuals with autism do perceive at least some facial expressions categorically. As this result is inconsistent with findings from other studies of categorical perception in individuals with autism, possible explanations for these findings are discussed.     

MEASURING SATISFACTION IN JEWISH “UTOPIA”

As a framework for social analysis, utopia is usually the province of classicists and political theorists. Yet practitioners of Jewish social studies — particularly specialists on the subject of the kibbutz — have much to offer non‐regional specialists of intentional communities and micropolities. Indeed, by applying standard social scientific techniques of survey and analysis, the kibbutz framework re‐emerges as a viable construct within contemporary comparative politics and sociology. Here, two similarly planned communities in the Negev desert, with founding memberships including a core (approximately one‐third) of “progressive” (i.e.Reform) Jewish emigrants from the USA, are analysed and compared statistically along several indices of satisfaction. Significant differences arise in the areas of personal relations, economic security, contentment with children’s education, and standard of living. Contrasting degrees of ideological and theological flexibility — attributable, in these two communities, to middle ageing and child rearing — may also account for different success outcomes. Measurement of satisfaction levels in Israel can help other neo‐utopian movements refine their proposed programmes and quantify their claims to superior socio‐political planning.     

Personal Construction of Family Relationships: The Relation of Commonality and Sociality to Family Satisfaction for Parents and Adolescents

This study tested the hypothesis that family members showing greater commonality (similarity) and sociality (predictive accuracy) in their construing of family relationships would display greater satisfaction with those relationships than would individuals in families whose relational construing was more discrepant and unpredictable. Forty-seven family triads participated in the study, including a mother, father, and adolescent from each family. Measures of commonality and sociality in the construction of family relationships derived from a family relationships grid were compared to measures of family structure, including the Family Cohesion and Adaptability Evaluation Scale (FACES-II) (Olson, Portner, & Bell, 1982) and the Parent-Adolescent Communication Scale (PACS) (Barnes & Olson, 1982). The findings suggest that members' perceptions of the family as emotionally close, flexible, and communicative may not represent independent aspects of the family structure, at least within the present nonclinical sample. Comparison of the family relationship grids with the FACES-H and PACS demonstrated that commonality and sociality among family members was highly related to mothers' and adolescents' family satisfaction, but was much less predictive of that of the father.     

Counselling asylum seekers and refugees: a study of Kurds in early and later stages of exile

This study explores the experience of asylum seekers and refugees in early and later phases of exile. Twenty-five Kurds (mainly asylum seekers) were interviewed in Greece in early phases of exile and twenty Kurds (mainly refugees) in later phases of exile in the UK. Refugee camps in Greece and community centres in London were the main locations for these interviews. Representatives from eight support organizations were also interviewed in each country. The multidimensional aspects of being a refugee are discussed, including models of formulating the experience, PTSD and the cross-cultural context. Key findings of the study include the desperate need among the asylum seekers and refugees, in the early phases, to have the story of their traumatic journey to Greece witnessed and validated by an outsider; the differing experiences of men and women; a change in identity over time; and considerable fear, which was evident in early and later phases. Moreover, all the support organizations expressed pronounced frustration but responded to it in different ways. Those organizations with supervision and support groups in place demonstrated more insight into their interactions with asylum seekers and refugees. Counselling approaches are evaluated with reference to the asylum seekers' and refugees' needs, and the desirability of adequate support for those with a counselling role is highlighted.     

Pushing the limits of task difficulty for the right and left hands in manual aiming

The effects of task difficulty on the performance of the two hands in right-handers were examined in a manual-aiming paradigm. In order to examine both simple and complex tasks, movement amplitude, cursor size, and target size were manipulated, resulting in eight different indices of difficulty (as defined by Fitts' Law). Kinematic parameters examined included reaction time, movement time, time to and time after peak velocity, peak velocity, and resultant accuracy. Analysis revealed no differential effects of task difficulty on the overall movement times of the two hands. These results are discussed in light of current theories of manual asymmetries.     

Levels of consensus and majority and minority influence

Three experiments are reported which examine the effects of consensus information on majority and minority influence. In all experiments two levels of consensus difference were examined; large (82% versus 18%) and small (52% versus 48%). Experiment 1 showed that a majority source had more influence than a minority source, irrespective of consensus level. Experiment 2 examined the cause of this effect by presenting only the source label (‘majority’ versus ‘minority’), only the consensus information (percentages) or both. The superior influence of the majority was again found when either (a) both source label and consensus information were given (replicating Experiment 1) and (b) only consensus information was given, but not when (c) only the source label was given. The results showed majority influence was due to the consensus information indicating more than 50% of the population supported that position. Experiment 3 also manipulated message quality (strong versus weak arguments) to identify whether systematic processing had occurred. Message quality only had an impact with the minority of 18%. These studies show that consensus information has different effects for majority and minority influence. For majority influence, having over 50% support is sufficient to cause compliance while for a minority there are advantages to being numerically small, in terms of leading to detailed processing of its message. Copyright © 2002 John Wiley & Sons, Ltd.     

Theory of mind and epistemological development: the relation between children's second-order false-belief understanding and their ability to reason about evidence

The study investigates the hypothesis that children's ability to attribute second-order beliefs facilitates their understanding of evidence, as seen in the ability to distinguish between causes and reasons. Seventy-four children 5–7 yr old were given belief and evidence tests. The belief tests assessed their ability to represent and reason from second-order false-beliefs, and the evidence tests assessed their ability to distinguish between the cause of a situation and a person's reason for believing it. The relation between performance on the two tests was determined, taking into account general language and non-verbal reasoning abilities. Results show that performance on the belief test and on the evidence part of the evidence test improved significantly over the age range, and that a significant proportion of variance in the evidence test scores is accounted for by second-order false-belief understanding, over and above that accounted for by general language and non-verbal abilities. The argument is made that second-order false-belief understanding is fundamental to children's epistemological development, underlying not just their understanding of evidence, but also their understanding of inference and truth.     

Visual agnosia and prosopagnosia in childhood: a prospective case study.

Selective impairments in visual processing are well documented in adults but rarely reported in children. The few childhood cases reported are mostly retrospective accounts with little attention paid to developmental, assessment or management issues. We report a prospective case study of a boy with prosopagnosia and visual processing deficits of presumed developmental origin. At the age of 4 years, AL presented with a range of cognitive and visual recognition deficits. Subsequent assessments revealed an evolving pattern in visual recognition and dissociations between developing skills. At the age of 7 AL has impairments in early perceptual analysis, visual organisation and in complex visual processing. Although he can identify facial features and match faces he is unable to recognise familiar faces. His reading and spelling are developing normally. The nature of his deficits and his progress are discussed within a cognitive neuropsychological framework.     

Recognition memory for tactile sequences.

In three experiments participants were required to compare the similarity in item order for two temporally separated sequences of tactile stimuli presented to the fingers of the hand. Between-sequence articulatory suppression but not tactile interference impaired recognition accuracy (Experiment 1), and the null effect of tactile interference was not due to the second tactile sequence overwriting the sensory record of the first sequence (Experiment 2). Experiment 3 showed that compared to a condition where the second sequence was presented in the tactile modality only, recognition was enhanced when the second sequence was seen presented either to the hand or on a diagrammatic representation of a hand. A final experiment showed that the effects of Experiment 1 were replicated when the underside of the forearm was used for stimulus presentation, suggesting that the data are not idiosyncratic to the first method of presentation. The pattern of results suggests memory for a sequence of tactile stimuli involves the deployment of strategies utilising a combination of verbal rehearsal and visuo-spatial recoding rather than relying solely on the retention of sensory traces. This is taken to reflect limitations in both the capacity and duration of tactile sensory memory.