A new challenge to ethical codes: Heart transplants

Summary We have entered into a new era of medical achievement with the development of successful transplantation of human organs. The transplantation of the heart has aroused the greatest scientific interest and at the same time created serious new problems of an ethical and legal nature. It has been necessary to develop new criteria to determine the moment of death of the donor in order to ensure continued life for the recipient. The decision of the moment of death should be made by a small team of skilled physicians interested in furthering this important development, but not as emotionally involved as are the surgeons awaiting the chance to prolong their patient's life with a new heart. Available and suitable hearts will probably always be in very short supply, and the selection of recipients will therefore become critical if the procedure proves to be widely acceptable.New laws will be essential before this process can be adopted in many states and countries. The cost in terms of total resources is so large that careful evaluation of the long-term results must be undertaken after a reasonable number of patients have been operated on and observed, perhaps at the end of the second year following the first procedure. Since the cost of each operation of this type approximates that of the education of several young physicians who could care for thousands of patients during their life span, a good hard look at the potential benefits and ultimate values is in order. At this point in time it is extremely important that this type of surgery be encouraged but limited to those prepared to undertake it with maximum skill and minimal risk. At present it must be recognized as a great experiment rather than a therapeutic triumph for general application.     

Contralateral and heteromodal interaction effects in somatosensation: Do they exist?

In this paper we concern ourselves with the problem of whether or not conditioning stimuli of other modalities or stimuli applied to a distant locus of the body interact with a sensitive test of somesthetic temporal acuity we have called the gap test. The results of the experiment indicate that visual stimuli do not exert an observable influence on this temporal judgment, but that auditory stimuli and contralateral stimulation in the same modality do show a significant but relatively small effect. This is compared and contrasted with the very large and persistent effect reported when the conditioning stimulus is applied to the same electrodes as the gap test. By comparing our results with experiments of similar design carried out on lower animals by other investigators, some insights into the neural localization of the reported effects is obtained.     

Escape behavior under continuous reinforcement as a function of aversive light intensity

In 11 male albino rats, lever-pressing responses, maintained under a CRF escape schedule with light as the aversive stimulus, were examined at each of five intensities, viz., 2.5, 18, 105, 190, and 386 ft-C. The function relating reciprocal of latency of the escape response to aversive light intensity passed through a maximum.     

Book reviews

The Word Speaks to the Faustian Man. Som Raj Gupta. Delhi, Motilal Banarsidass. 455+xvi pp., Rs. 500

A History of Indian Buddhism, From Sākyamuni to Early Mahāyāna. Hirakawa Akira, translated and edited by Paul Groner, 1990. Asian Studies at Hawaii, No. 36. Honolulu, HI, University of Hawaii Press. xix +402, £33.25

The Doctrine of the Upanisads and the Early Buddhism. Hermann Oldenberg, translated by Shridhar B. Shrotri, 1991. Delhi, Motilal Banarsidass. Rs. 225

Evil and the Mystics’ God: Towards a Mystical Theodicy. Michael Stoeber. London, Macmillan. x+225 pp., £40     

PIGEONS ARE SENSITIVE TO THE SPATIAL ORGANIZATION OF COMPLEX VISUAL STIMULI

Abstract— Two experiments investigated the role of spatial organisation in the discrimination and generalization of complex visual stimuli by pigeons. In Experiment 1, after pigeons had been trained to discriminate line drawings of four objects, they were tested with novel pictures in which the same component parts of the objects were spatially rearranged. The spatially scrambled pictures led to a dramatic drop in recognition accuracy, hut responding remained above chance. In Experiment 2, pigeons reached a high level of discriminative performance when required to choose among four different spatial arrangements of the same object parts. These results confirm Cerella's (1980) conclusion that pigeons discriminate the component parts of complex visual stimuli, but. unless it is assumed that the scrambling deleted or created emergent features, the results disconfirm his conclusion that spatial organization plays no role in pigeons' picture perception.     

Nonsuicidal physically self-damaging acts in adolescents

To determine the frequency and correlates of nonsuicidal physically self-damaging acts in 12–14 year olds, a two stage epidemiologic survey with a self-administered questionnaire (N=3283) followed by a psychiatric interview of a subsample of the adolescents and their parents (N=444) was used. Prevalence estimates of interview validated nonsuicidal physically self-damaging acts were 2.46% in males and 2.79% in females. Significant relationships were found between nonsuicidal physically self-damaging acts and suicidal ideation, major depression and undesirable life events. Data suggest that physically self-damaging acts occur at substantial rates during early adolescence. The strong correlation between nonsuicidal self-destructive acts and both suicidal ideation and major depression clarifies prior conflicting reports in the literature and suggests that a history of self-damaging acts should be taken into consideration when evaluating for possible depression and suicide risk.     

Dynamic spatial performance and general intelligence

A computerized video-game-like dynamic spatial ability measure and a paper-and-pencil group test of intelligence were administered to 94 university students. The purpose of the study was threefold: (a) to evaluate the reliability of the dynamic spatial measure; (b) to investigate the extent to which the dynamic spatial measure is saturated with variance associated with traditional measures of fluid and crystallized intellectual ability; and (c) to explore the possibility that dynamic computer based performance measures define factors that are distinct from those associated with traditional paper-and-pencil measures. The number of times the participant hit a moving target served as the dependent variable for the dynamic spatial measure. Number of hits proved to be correlated with Performance IQ, but was not significantly correlated with Verbal IQ. Maximum likelihood factor analysis revealed that the dynamic spatial measure did not load substantially on a factor of general intellectual ability but provided additional evidence that it is related to a performance component.