Effects of nicotine deprivation on alcohol-related information processing and drinking behavior

This study examined the influence of smoking cues and nicotine deprivation on responses to alcohol among hazardous drinkers. Fifty-six daily smoking, hazardous drinkers were exposed to either smoking cues or control cues after either 6 hr of nicotine deprivation or no deprivation. Urges to drink alcohol, alcohol-related cognitive processing, and alcohol consumption were assessed after cue exposure. Results indicated that nicotine deprivation increased urges to drink, the accessibility of alcohol outcome expectancies, and the volume of alcohol consumed. There was little influence of the smoking cue manipulation on these processes. Implications for understanding the mechanisms underlying alcohol-tobacco interactions are discussed.     

Effects of reserpine on retention of escape reversal in mice: absence of state-dependent learning.

A discriminated escape training paradigm was used to study the effects of reserpine on learning and memory in mice. Intraperitoneal injection of reserpine before reversal training had no effect on acquisition but did produced a time-and dose-dependent impairment of retention test performance 10 days later. These results suggested that reserpine may have interfered with some aspect of memory storage. Retention impairments observed when a 2.0 mg/kg reserpine injection was given 2 hr before reversal training were not attenuated by readministering the drug before testing, a finding that provides no support for a state-dependency interpretation. Furthermore, animals treated with reserpine exhibited inferior retention of previous training, regardless of the pharmacological state present during that learning. This was interpreted as a drug-induced impairment of memory retrieval. In addition, performance during the initial discriminated escape training session suggested that reserpine may also impair acquisition under some conditions. In the last experiment, it was found that when the catecholamine precursor L-dihydroxyphenylalamine (100 mg/kg) and the indole amine precursor D,L-5-hydroxytryptophan (125 mg/kg) were both given after reserpine treatment, subsequent retention performance was not significantly impaired. The results are discussed in terms of the possible roles of biogenic amines in arousal, learning, and memory.     

Theory of mind and rule-based reasoning

The hypothesis is tested that during the preschool period a particular form of reasoning is applied to theory of mind and a set of problems that do not require the understanding of mental states. Three experiments each provided a different piece of support for this hypothesis. Experiment 1 found similar age-related changes between three standard theory-of-mind tasks (false belief, appearance-reality and representational change) and two specially designed nonmental state tasks (rule-based card sorting and physical causality). Experiment 2 demonstrated that 3-year-olds' poor performance on card sorting occurred across different pairs of dimensions (color-size, shape-number, size-number, color-shape) just as it does across different pairs of perspectives in the theory-of-mind tasks (self-other, looks like-is, before-after), and that sorting performance was related to theory of mind with age partialled. Experiment 3 showed that theory of mind was related to a specific complexity of sorting—sorting by one of two dimensions and not sorting by one dimension or two dimensions simultaneously. The results indicate that advances in theory of mind, card sorting, and causality between 3 and 5 years of age depend on being able to switch judgments across conditions and that reasoning by embedded rules could account for these changes.     

Effects of temptations on the affective salience of weight control goals

Despite the value of weight control goals, the maintenance of healthy eating habits represents a challenge for most. Self-regulatory efforts are often challenged by the presence of high-risk cues (e.g., tempting foods) which provide short-term positive outcomes at the expense of these long-term health objectives. The current study examined contextual influences on self-regulation failure by exploring the effect of cues on an indirect measure of goal value. Two experiments were conducted with undergraduate students which examined the effect of temptation cues on the evaluation of information related to the goal of weight control. Results of Study 1 provided preliminary evidence for the utility of this task as an indirect measure of goal value and showed that food-related primes slowed evaluation response times for weight control-related targets. Study 2 replicated and extended these findings by demonstrating that temptation cues may not only decrease the affective salience of weight control related information but increase the salience of information related to the goal of affect enhancement. These results suggest that self-regulation failure may be influenced by contextual changes in the value of health-related goals. Implications for prevention and intervention efforts are discussed.     

Effects of depressed mood on drinking refusal self-efficacy: examining the specificity of drinking contexts

College students with elevated depressive symptoms are more likely to engage in risky drinking and experience alcohol-related negative consequences. Efforts to understand the association between depressed mood and alcohol use have begun to identify the role of cognitive-motivational processes. Drinking refusal self-efficacy is one such process that influences the decision to drink, but its relationship with depressed mood remains unclear. The current study sought to clarify the role of these processes using a depressed mood induction procedure in a sample of college student drinkers. Eighty-six students were randomized to a depressed or neutral mood induction and completed assessments of drinking refusal self-efficacy. Depressed mood significantly decreased self-efficacy in high-risk drinking contexts related to depression, whereas ratings of other high-risk contexts were unaffected. These findings suggest that the association between hazardous drinking and depressed mood may be due in part to the direct influence of mood state on one's self-efficacy to resist drinking in relevant contexts.     

Are needs to manage uncertainty and threat associated with political conservatism or ideological extremity?

Three studies are conducted to assess the uncertainty- threat model of political conservatism, which posits that psychological needs to manage uncertainty and threat are associated with political orientation. Results from structural equation models provide consistent support for the hypothesis that uncertainty avoidance (e.g., need for order, intolerance of ambiguity, and lack of openness to experience) and threat management (e.g., death anxiety, system threat, and perceptions of a dangerous world) each contributes independently to conservatism (vs. liberalism). No support is obtained for alternative models, which predict that uncertainty and threat management are associated with ideological extremism or extreme forms of conservatism only. Study 3 also reveals that resistance to change fully mediates the association between uncertainty avoidance and conservatism, whereas opposition to equality partially mediates the association between threat and conservatism. Implications for understanding the epistemic and existential bases of political orientation are discussed.     

Meaning in life goal pursuit moderates the effects of social influences on college student drinking

This study sought to examine whether life goal meaning serves as a protective factor against the effects of social influences on hazardous drinking. The sample consisted of 156 college drinkers who had consumed alcohol in the past 30 days. Results indicated that goal meaning moderated the relation between both injunctive norms and direct offers and heavy drinking episodes. Simple slopes' analyses showed that injunctive norms predicted heavy episodic drinking for students with low but not high levels of goal meaning. Direct offers predicted heavy episodic drinking, however, the strength of this association was reduced at high levels of goal meaning. Results suggest that higher levels of goal meaning may buffer the effects of social influences on college student hazardous drinking.