The effects of stressor predictability on lymphocyte proliferation in humans

Abstract

To demonstrate the effects of predictable and unpredictable stressors on immune function, 36 male subjects were randomly assigned to complete ten trials of either a predictable or unpredictable cold pressor task or a non-stressful warm pressor control task. The predictable and no-stressor groups were given information about the duration of each pressor trial and a countdown of seconds passed from beginning to end of each trial. The unpredictable stressor group received no information. Self-report, cardiovascular, and biochemical measures were taken throughout the tasks in order to ascertain the effectiveness of the predictability and stressor manipulations. Lymphocyte proliferation to concanavalin A (Con A) and pokeweed mitogen (PWM) were measured before, during and after the tasks. Lymphocyte proliferation to Con A (10/μg/ml) was significantly reduced only in response to the unpredictable stressor suggesting that predictability buffered the effect of the stressor on immune function. Proliferation to PWM followed a similar pattern but was not statistically significant. Blood pressure responses were negatively correlated with proliferation values suggesting that stressor predictability may attenuate stress-associated immune decreases by reducing sympathetic arousal.     

Structural studies of ultrathin zirconia dielectrics

We present detailed structural and chemical studies on ultrathin zirconia films grown by ultraviolet oxidation and natural (no ultraviolet light) oxidation of Zr precursor metal layers on SiO2-passivated Si(100) wafers. Quantitative electron-energy-loss spectroscopy (EELS) was used to obtain the chemical composition and electronic structure on an atomic scale. The EELS OK near-edge fine structure was used as a fingerprint to study the stoichiometry and composition variation in the dielectric stacks. X-ray absorption spectroscopy studies were performed in order to aid interpretation of the EELS results. The electronic structure data are correlated with the electrical performance of the films.     

An Inquiry into Views,Beliefs and Faith: Lessons from Buddhism,Behavioural Psychology and Constructivist Epistemology*

Abstract

 The causes of disagreements between individuals, social groups, cultural groups, political parties, and nations can be traced down to the basic human tendency to give form to – and to reify views, beliefs, and opinions. With this being the case, I would like to ask the question: what, exactly are ‘views’ (including here such overlapping categories as ‘opinions’, ‘beliefs’ and ‘attitudes’,)? How, exactly, do we give form to them? Why is it so difficult to change, or get rid of them? The Buddhist tradition since the time of its inception, has been greatly concerned with the matter of identifying ‘false views’ and replacing them with ‘correct views’. But serious and insightful research into the formation and maintenance of views and beliefs is by no means limited to Buddhism. It has been a topic of great concern in the past century to a wide range of secular researchers: social and behavioural psychologists; literary theorists and epistemologists; scientists and marketing strategists. What the specialists in these various fields have to say about beliefs is diverse – and yet there is much overlap. The ways in which they overlap are thought-provoking, and their differences are revelatory. In this paper, I investigate a few prominent approaches to the study of views and beliefs, and show how these various approaches can do much to fill in each other’s discourse. Finally, I reframe the Mahayana Buddhist notion of ‘correct faith’ within the context of this exploration of views.     

Visual Search for Conjunctions of Motion and Form: The Efficiency of Attention to Static versus Moving Items Depends on Practice

Visual search for some motion-form conjunctions can be performed in parallel. Yet, if the target is easy to discriminate from the nontargets (target line tilted 45 from the vertical), search can be easier for a moving than for a stationary target. Driver and McLeod (1992; Berger & McLeod, 1996) took this asymmetry to argue that gross aspects of form discrimination are performed within a motion filter thatrepresents only the moving items, whereas discrimination of stationary items (and all fine discrimination) relies on a static form system. However, recent (unsuccessful) attempts to replicate the asymmetry (Muller & Found, 1996; Muller & Maxwell, 1994) suggested that it may occur only early during task performance, due to participants having difficulty keeping the moving items out of the search for a stationary target (but not vice versa). This was confirmed by the present study, which investigated the effects of practice on search among the moving and stationary subset of items. The results suggest that attention to the stationary subsetis difficultinitially because participants cannotefficiently compensate for the natural bias of the motion filter to pass the moving items (rather than filter them out). This ability improves with practice. Thus, there is no fixed limit to performance with stationary targets and, consequently, no need to assume that any form discrimination is performed within the motion filter.     

Cultural Specificity in Patterns of Mental Illness and Health: A Slovak-American Case Study

Mental illness and mental health are conceptualized as dynamic opposites o/a single, underlying psycho-cultural process. An illustrative case history of a Slovak-American family with a schizophrenic member is presented.