Glucose modulation of memory storage processing

Epinephrine, derived from the adrenal medulla, enhances memory storage for several forms of learning. One physiological action of this hormone is to liberate hepatic glucose stores. This experiment tested the possibility that glucose could itself enhance memory. Rats were water deprived, pretrained to drink, pretrained to drink in the behavioral apparatus, and then trained in a one-trial inhibitory (passive) avoidance task. Immediately after the training footshock, the animals each received an injection of glucose (1.0-500 mg/kg). When tested for retention 24 h later, the animals which received 10 or 100 mg/kg doses of glucose exhibited enhanced retention performance; higher and lower doses had no significant effect on the memory tests. Also, glucose injections (100 mg/kg) delayed by 1 h after training had no effect on the retention tests. These findings suggest that the increase in plasma glucose levels subsequent to epinephrine injection may contribute to the effects of epinephrine on memory. In addition, the results suggest that peripheral glucose levels may exert important influences on memory storage.     

An evaluation of the family adaptability and cohesion evaluation scales and the circumplex model

Two basic assumptions of the Circumplex Model of family systems were evaluated: (1) Healthy families evidence balanced degrees of cohesion and adaptability, whereas problem families evidence extreme degrees, and (2) families with balanced degrees of cohesion and adaptability possess more positive communication skills than families with extreme degrees. Subjects were 58 mother-son dyads from father-absent families. In 29 of the families the adolescent was a juvenile offender, while in the remaining families there was no history of arrest or psychiatric referral. The dyads completed the Family Adaptability and Cohesion Scales (FACES) and an unrevealed differences interaction task. FACES was highly proficient at differentiating delinquent from nondelinquent families. Moreover, in families with balanced degrees of cohesion and adaptability, the mothers' communication was significantly more supportive and explicit, and the dyads evidenced significantly greater warmth and affection than dyads with extreme degrees.This research was supported by funding to the Department of Psychology at Memphis State University granted through the Centers of Excellence Program of the State of Tennessee. We thank the staff of the Memphis-Metro Youth Diversion Project for their consideration and assistance.     

Assessment of anxiety and achievement in kindergarten and first-and second-grade children

The psychometric properties of the State-Trait Anxiety Inventory for Children (STAIC) and relationships between STAIC T-Anxiety scores and standardized measures of achievement were determined for 948 kindergarten and first-and second-grade children. The T-anxiety scores of kindergarten children were lower than those of first-and second-graders. Internal consistency of the STAIC scales was higher in individual testing sessions than in small group administrations. Small but significant negative correlations were found between STAIC T-Anxiety scores and measures of school achievement. It was concluded that the STAIC is a potentially useful measure of state and trait anxiety in kindergarten through sixth-grade children, but it must be administered individually at the kindergarten and first-grade levels.The research was performed while the senior author was a senior research scientist at the Dallas Independent School District.     

Foundations of a new system of probability theory

The aim of my book is to explain the content of the different notions of probability.Based on a concept of logical probability, which is modified as compared with Carnap, we succeed by means of the mathematical results of de Finetti in defining the concept of statistical probability.The starting point is the fundamental concept that certain phenomena are of the same kind, that certain occurrences can be repeated, that certain experiments are identical. We introduce for this idea the notion: concept K of similarity. From concept K of similarity we derive logically some probability-theoretic conclusions:If the events E() are similar —of the same kind - on the basis of such a concept K, it holds good that intersections of n of these events are equiprobable on the basis of K; in formulae: E(₁)...E( _{n K} E('₁)...E(' _n , _{i j} ,' _j ' _j for ij On the basis of some further axioms a partial comparative probability structure results from K, which forms the starting point of our further investigations and which we call logical probability on the basis of K.We investigate a metrisation of this partial comparative structure, i.e. normed -additive functions m _K, which are compatible with this structure; we call these functions m _K measure-functions in relation to K.The measure-functions may be interpreted as subjective probabilities of individuals, who accept the concept K.Now it holds good: For each measure-function there exists with measure one the limit of relative frequencies in a sequence of the E().In such an event, where all measure-functions coincide, we speak of a quantitative logical probability, which is the common measure of this event. In formulae we have: l _K (h _n lim h _n )=1 in words: There is the quantitative logical probability one that the limit of the relative frequencies exists. Another way of saying this is that the event ^* (h_n lim h _n) is a maximal element in the comparative structure resulting from K.Therefore we are entitled to introduce this limit and call it statistical probability P.With the aid of the measure-functions it is possible to calculate the velocity of this convergence. The analog of the Bernoulli inequation holds true: m _K (¦h _n –P¦)1–1/4n².It is further possible in the work to obtain relationships for the concept of statistical independence which are expressed in terms of the comparative probability.The theory has a special significance for quantum mechanics: The similarity of the phenomena in the domain of quantum mechanics explains the statistical behaviour of the phenomena.The usual mathematical statistics are explained in my book. But it seems more expedient on the basis of this new theory to use besides the notion of statistical probability also the notion of logical probability; the notion of subjective probability has only a heuristic function in my system.The following dualism is to be noted: The statistical behaviour of similar phenomena may be described on the one hand according to the model of the classical probability theory by means of a figure called statistical probability, on the other hand we may express all formulae by means of a function, called statistical probability function. This function is defined as the limit of the relative frequencies depending on the respective state of the universe. The statistical probability function is the primary notion, the notion of statistical probability is derived from it; it is defined as the value of the statistical probability function for the true unknown state of the universe.As far as the Hume problem, the problem of inductive inference, is concerned, the book seems to give an example of how to solve it.The developed notions such as concept, measure-function, logical probability, etc. seem to be important beyond the concept of similarity.The present work represents a summary of my book Grundzüge zu einem neuen Aufbau der Wahrscheinlich-keitstheorie [5], For this reason, I have frequently dispensed with providing proof and in this connection refer the interested reader to my book.     

Social adjustment in the offspring of parents with bipolar affective disorder

The social adjustment of the adolescent offspring of parents with bipolar affective disorder (n=41) was compared to that of the offspring of parents with nonaffective psychiatric disorders (n=22) and the offspring of normal controls (n=26). In addition, the relationship between social adjustment and cyclothymia in offspring was determined. Social adjustment was assessed using the Life Activities Inventory, a new measure developed to assess social functioning in adolescents and young adults. Cyclothymia was assessed with the General Behavior Inventory. As a group, the offspring of bipolar parents did not differ significantly from either control group on social adjustment. However, the cyclothymic offspring of bipolar parents exhibited significantly poorer social adjustment than the noncyclothymic offspring of bipolars and the offspring of psychiatric and normal controls. These findings suggest that poor social functioning in the adolescent offspring of parents with bipolar illness may be associated with the early manifestations of affective disorder. In addition, these data indicate that despite its subsyndromal intensity, cyclothymia can result in significant social impairment.This study was supported in part by National Institute of Mental Health (NIMH) Research Grant MH-39782 to Daniel N. Klein and NIMH Grants MH-33083 and MH-37195 to Richard A. Depue.