Psychotropic drug treatment among learning-disabled,educable mentally retarded,and seriously emotionally disturbed students

Psychotropic drug treatment in learning-disabled (LD), educable mentally retarded (EMR), and seriously emotionally disturbed (ED) children and adolescents receiving public school special education services was examined. The findings indicated that while treatment prevalence rates for EMR and ED groups were comparable, the rate for LD students was much lower. In the LD sample, pharmacotherapy was associated with higher ratings of behavioral deviance, longer placement in special education, less social integration, and greater peer rejection, which suggests that symptom severity is an important determiner of pharmacotherapy in this population.     

A comparison of the relative efficacy of self-control therapy and a behavioral problem-solving therapy for depression in children

Twenty-nine children 9 to 12 years old who were identified as moderately to severely depressed using the Children's Depression Inventory were randomly assigned to either a self-control, behavioral problem-solving, or waiting list condition. The self-control treatment focused on teaching children self-management skills. The behavioral problem-solving therapy consisted of education, self-monitoring of pleasant events, and group problem solving directed toward improving social behavior. Subjects were assessed pre-and posttreatment and at 8-week follow-up with multiple assessment procedures and from multiple perspectives. At posttreatment, subjects in both active treatments reported significant improvement on self-report and interview measures of depression while subjects in the waiting list condition reported minimal change. Results were maintained at follow-up. The general success of the experimental treatments was discussed and recommendations for further treatment components were provided.Second authorship on this article is shared by Drs. Reynolds and Kaslow. The authors would like to thank Mr. Ed Guzwieski, Principal, and the teachers of Oregon Middle School for their cooperation with this study. The authors also would like to thank Mary Wysopal for conducting the posttreatment and follow-up interviews, and Carol Fairbanks for rating the audiotapes.     

Hyperphagia resulting from gut denervation in the sea slug, Pleurobranchaea

Previous research suggests that gut distension by ingested bulk plays an important role in the regulation of food intake in gastropod molluscs. The present study tested whether the bilateral stomatogastric nerves which innervate the esophagus and crop in Pleurobranchaea form a neural pathway carrying information about gut distension to the central nervous system. The posterior branches of the paired stomatogastric nerves were surgically exposed and sectioned in seven experimental animals while the nerves were simply exposed and not sectioned in seven sham-operated control animals. In three, subsequent, daily feeding sessions, the experimental subjects consumed a greater amount of food in terms of percentage of body weight than the control subjects. The experimental animals also gained a greater percentage of body weight and later were found to contain much more food within their guts. The results support the hypothesis that stretch receptors which innervate the gut and which have axons in the stomatogastric nerves form an important negative feedback pathway for the control of feeding in the sea slug.     

Modulation of male mouse sniff, attack, and mount behaviors by estrous cycle-dependent urinary cues

Modulation of male urogenital sniff, attack, and mount behaviors by urinary cues from female mice (SJL/J) was assessed in two experiments. Experiment 1 examined the efficacy of urine from ovariectomized and intact females in modulating the behavior of sexually experienced and inexperienced males vis-à-vis the control substance, water. It was found that urine from ovariectomized females showed no behavior-modulating properties, whereas urine from intact females decreased attack but increased sniff and mount behaviors in male mice. These findings are indicative of ovarian-dependent chemosignals contained in the urine of only intact females. Prior sexual experience had no effect on behavior of males when exposed to urine from ovariectomized females. Sniff and mount behaviors were, however, increased when sexually experienced males were exposed to urine from intact females. Using sexually inexperienced males, Experiment 2 assessed the chemosignal activity of urine from females in each of four estrous phases. It was determined that urine from proestrous and estrous females increased sniff and mount behaviors and decreased attack behavior. Urine from metaestrous females was shown to possess only sniff-inducing and mount-reducing chemosignal properties. Urine from females in diestrous lacked attack- and mount-modulating chemocues but may possess a sniff-inducing chemosignal.     

Individual differences in cognitive arithmetic

Unities in the processes involved in solving arithmetic problems of varying operations have been suggested by studies that have used both factor-analytic and information-processing methods. We designed the present study to investigate the convergence of mental processes assessed by paper-and-pencil measures defining the Numerical Facility factor and component processes for cognitive arithmetic identified by using chronometric techniques. A sample of 100 undergraduate students responded to 320 arithmetic problems in a true-false reaction-time (RT) verification paradigm and were administered a battery of ability measures spanning Numerical Facility, Perceptual Speed, and Spatial Relations factors. The 320 cognitive arithmetic problems comprised 80 problems of each of four types: simple addition, complex addition, simple multiplication, and complex multiplication. The information-processing results indicated that regression models that included a structural variable consistent with memory network retrieval of arithmetic facts were the best predictors of RT to each of the four types of arithmetic problems. The results also verified the effects of other elementary processes that are involved in the mental solving of arithmetic problems, including encoding of single digits and carrying to the next column for complex problems. The relation between process components and ability measures was examined by means of structural equation modeling. The final structural model revealed a strong direct relation between a factor subsuming efficiency of retrieval of arithmetic facts and of executing the carry operation and the traditional Numerical Facility factor. Furthermore, a moderate direct relation between a factor subsuming speed of encoding digits and decision and response times and the traditional Perceptual Speed factor was also found. No relation between structural variables representing cognitive arithmetic component processes and ability measures spanning the Spatial Relations factor was found. Results of the structural modeling support the conclusion that information retrieval from a network of arithmetic facts and execution of the carry operation are elementary component processes involved uniquely in the mental solving of arithmetic problems. Furthermore, individual differences in the speed of executing these two elementary component processes appear to underlie individual differences on ability measures that traditionally span the Numerical Facility factor.(ABSTRACT TRUNCATED AT 400 WORDS)     

Structure and process in semantic memory: new evidence based on speed-accuracy decomposition

Reaction-time and accuracy data obtained from studies of sentence verification have not been rich enough to answer certain important theoretical questions about structures and processes in human semantic memory. However, a new technique called speed-accuracy decomposition (Meyer, Irwin, Osman, & Kounios, 1986) may help solve this problem. The technique allows intermediate products of sentence verification to be analyzed more precisely. Three experiments with speed-accuracy decomposition indicate that verification processes produce useful partial information before they are completed. Such information appears to accumulate continuously at a rate whose magnitude depends on the degree of relatedness between semantic categories. This outcome is consistent with continuous computational (e.g., semantic-feature comparison) models of semantic memory. An analysis of reaction-time minima suggests that a discrete all-or-none search process may also contribute at least occasionally to sentence verification. Further details regarding the nature of these processes and the memory structures on which they operate can be inferred from additional results obtained through speed-accuracy decomposition.     

Time horizons in rats foraging for food in temporally separated patches

An important tenet of optimal foraging theory is that foragers compare prey densities in alternative patches to determine an optimal distribution of foraging behavior over time. A critical question is over what time period (time horizon) this integration of information and behavior occurs. Recent research has indicated that rats do not compare food density in a depleting patch with that in a rich patch delayed by an hour or more (Timberlake, 1984). In the present research we attempted to specify over what time period a future rich patch would affect current foraging. The effect of future food was measured by early entry into the rich patch (anticipation) and by a decrease in food obtained in the depleting patch (suppression). The rats showed anticipation of a rich patch up to an hour distant, but suppressed current feeding only if the rich patch was 16 min distant or less. The suppression effect appeared mediated by competition for expression between anticipatory entries into the rich patch and continued foraging in the depleting patch. These results suggest that optimal foraging is based on a variety of specific mechanisms rather than a general optimizing algorithm with a single time horizon.     

Social structure features in three inbred strains of mice, C57Bl/6J, Balb/cj, and NIH: a comparative study

Some features of social living were investigated in three inbred strains of mice: C57Bl/6j, Balb/cj, and NIH. Five social behaviors--Aggression, Submission, Allogrooming, Social Rest and Rest Alone, as well as Wheel Running Activity--were recorded 2 h daily for a week, in 26 groups of seven male mice living in an enriched environment. Dominants and subordinates among strains shared some behavioral characteristics, but strain contributions upon social structure were also detected. Similarities among strains included the appearance of a single dominant mouse per group rated as the most aggressive, besides from being the animal presented with most Submissions. Allogrooming was more frequent among subordinates than among dominants and subordinates. Differences among strains were that agonistic behavior among subordinates was higher in the Balb/cj and NIH groups than in the C57Bl/6j mice. NIH mice were recorded in Rest Alone more often than mice from the other strains. C57Bl/6j dominants showed higher rates of Wheel Running Activity than subordinates.     

Long-term memory formation in chicks is blocked by 2-deoxygalactose, a fucose analog

When day-old chicks are trained on a passive avoidance task there is enhanced synthesis of glycoproteins. Bilateral intracerebral injections of 20 mumole of 2-deoxygalactose (2-D-gal), administered just before and just after training on the task, produce amnesia for the avoidance. Amnesia develops slowly over the first hour and persists for at least 24 h subsequently. If 2-D-gal injections are administered 4 h prior to the training or delayed for 3 h after training, no amnesia occurs. Apart from a brief initial suppression of pecking following injection there are no effects of 2-D-gal on other observed behaviors of the birds. Within the first hour this dose of 2-D-gal inhibits [3H]fucose incorporation into acid-insoluble material by 26% (or 68%, calculated relative to free pool fucose). The amnestic effect of 2-D-gal is not shown by galactose, glucose, fucose, or 2-D-glucose. Injecting 40 mumole of galactose simultaneously with the 2-D-gal abolishes the 2-D-gal-induced amnesia; 40 mumole of fucose, however, does not abolish the amnesia. The utility of 2-D-gal as an agent for analyzing the role of glycoproteins in memory formation is discussed.     

Kinematic form and scaling: further investigations on the visual perception of lifted weight

Observers are able to judge accurately the weight lifted by another person when only the motions of reflective patches attached to the lifter's major limb joints and head can be seen (Runeson & Frykholm, 1981). What properties of these complex kinematic patterns allow judgments of weight to be made? The pattern of variation in velocity of the lifted object over position is explored as a source of information for weight: It is found to provide limited information. How are variations in kinematic patterns scaled to allow judgments of weight, a kinetic quantity? The possibility of a source of information for scaling in the kinematics is investigated. Judgments based only on patch-light displays are accurate to a degree that is improved by an extrinsic scaling basis. Finally, the sensitivity to scaling of alternative metrics used in judging is explored. Intrinsic metrics are discovered to be less sensitive to the absence of an extrinsic basis for scaling.