Effects of d-amphetamine on self-aggression and posturing in stumptail macaques

The behavioral effects of d-amphetamine sulfate were studied in adult male stumptail macaques living within a large heterogeneous group in an outdoor enclosure. Among five subjects that received a range of doses (.01 to .3 mg/kg), d-amphetamine increased self-aggressive behavior and abnormal posturing in subjects that exhibited these types of behavior prior to drug administration, but it had no effect in subjects not exhibiting those activities in the absence of the drug. For the former subjects, the dose-effect curves for self-aggression were of an inverted U-shape analogous to the effect of d-amphetamine on schedule-controlled behavior. Over the range of doses studied, the curve for abnormal posturing was monotonic. The data indicate that d-amphetamine can have effects on untrained behavior in individual animals in a quasinatural environment that are qualitatively and quantitatively similar to the behavioral effects observed in other laboratory environments, and that d-amphetamine does not evoke or increase a behavioral response in individual subjects that do not exhibit the response in the absence of the drug.     

Stimulus control of responding by response-reinforcer temporal contiguity

The stimulus properties of brief disruptions in response-reinforcer temporal contiguity were investigated using a discrete trial conditional discrimination procedure. Key pecking (nondelay) or key pecking followed by a brief interval of nonpecking (delay) in the sample component produced a stimulus change (choice component). Pecks in the choice component to one of two alternatives resulted in food or blackout, conditional upon which response requirement was met in producing the choice component. A baseline condition, in which key pecking always produced the choice component and correct choices were arranged randomly, alternated with experimental conditions that included nondelay and delay values of either 0.2, 0.5, or 1.0 sec between the last key peck and the initiation of the choice component. All subjects accurately discriminated brief temporal delays between a response and stimulus change, with choice accuracy increasing for three of four subjects as the temporal disruption in contiguity increase. Implications of the research for the study of delayed reinforcement, response-independent reinforcement, and the discrimination of causality are discussed.     

Concurrent schedules: Spatial separation of response alternatives

Four pigeons were exposed to independent concurrent variable-interval 20-second variable-interval 60-second schedules of reinforcement. A transparent partition was inserted midway between the two response keys. The length of the partition was systematically manipulated. Increasing partition length produced a decrease in changeover rate in Experiment 1. Over-matching was observed with a partition length of 20 centimeters. In Experiment 2 a four-second limited hold was added to the schedules. Increasing partition length produced a decrease in changeover rate that exceeded the decrease observed in Experiment 1. This manipulation produced nearly exclusive choice of the variable-interval 20-second component. The present results, together with results obtained in related research, suggest that deviation from matching is a function of procedural variables that determine the consequences of a changeover response.     

Duration-reduction of avoidance sessions as negative reinforcement

Five rats were exposed to a shock-postponement procedure in which responses on each of two levers initially had equivalent effects. After an initial training sequence that ensured at least some responding on each lever, an additional consequence was made conjointly operative on the previously less-preferred lever for each animal. Each response on this lever continued to postpone shock, but also reduced the session duration by one minute. The conjoint contingencies were operative until, through session-shortening responses and the passage of time, the session was scheduled to end in two minutes; during the final two minutes the session-shortening contingency was disabled while the shock-postponement contingency continued to be operative on both levers. When responding shifted to a predominance on the session-shortening lever, the conjoint contingency was shifted to the other lever; for four of the five rats this reversal was followed by two additional reversals. Two of the rats' responding showed clear, strong, and unambiguous sensitivity to the session-shortening contingency. The responding of two others was also systematically controlled by that contingency, but the effects were less clearcut. The fifth animal showed an initial shift when session-shortening was introduced, but its subsequent behavior proved insensitive to reversals of procedure. The results clearly indicate a sensitivity of behavior to events on a time scale quite distinct from that of immediate consequences. They also support an interpretation of avoidance sessions, considered in their entirety, as events whose contingent relationship to behavior can affect that behavior—even in the absence of stimuli that delineate those relationships. Finally, these results support an interpretation of aversively based conditioning within a broader context, analogous to the “open versus closed economy” interpretation of appetitively controlled behavior.     

Effect of lingual vibrotactile stimulation on the averaged cortical evoked response

This study was designed to determine the feasibility of using lingual vibrotactile stimulation to elicit an averaged evoked response and to investigate the effects of two supra-threshold intensity levels of lingual vibrotactile stimulation on the electro-cortical activity of the brain. The evoked responses were analyzed according to the amplitude of N1-P2 (in microvolts). Analysis indicates that the tongue can successfully be used as a stimulus site in the elicitation of an evoked response. The amplitudes of the evoked response elicited by 2 micrometers sensation level and 5 micrometers sensation level on the tongue are essentially the same. The relative difference between these levels is not sufficient to produce significant differences in the amplitudes of their respective evoked responses.     

Complex form of instrumental behavior of dogs

A complex form of higher nervous activity, conditional reflex transswitching or switching, was elaborated in four dogs under conditions of unrestrained movements, freedom of reinforcement choice (food or water), place of reinforcement determined by situation factors as well as independent switching on of conditional stimuli. It was shown that motivated goal-directed behavior of the animals was determined by activation of forward and backward connections. The chains of instrumental conditioned reflexes forming in the final analysis the complex behavior are developed according to the “trialand-error” principle. In the instrumental conditioned reflexes there are two constantly coexisting types of mutually complementing conditioned connections of the signal with reinforcement—direct and indirect. In experiments with unrestrained conditions of animals and independent regulation of the experiment, one of the frequently encountered physiological mechanisms of generalization appears to be efferent and afferent generalization.     

The MMPI'S of left- and right-handed subjects

Previous research has suggested that left-handedness relates to delinquency and violence. In an effort to pinpoint the nature of this apparent relationship, we compared the MMPIs of 72 left- and 687 right-handed men 60 yr. old or less on an alcohol treatment ward. No significant differences appeared. The results are compared to earlier research and hypotheses for further research are suggested.