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Individual differences in cortical anatomy are readily observable, but their functional significance for behaviors such as reading is not well understood. Here, we report a case of an apparent compensated dyslexic who had attained high achievement in visuospatial mathematics. Data from a detailed background interview, psychometric testing, divided visual field tasks measuring basic word recognition (word naming, nonword naming, and lexical decision), and more controlled word retrieval (verb, category, and rhyme generation), and measurements of his atypical brain structure are described. The findings suggested that enhanced "top-down" processing could provide the means to compensate for deficient "bottom-up" word decoding skills in this case. Relative to controls, this individual also evidenced unusually large asymmetries on several divided visual field lexical tasks, an extreme leftward asymmetry of the planum temporale, and a rare form of Sylvian fissure morphology (Steinmetz type 4, [Steinmetz, H., Ebeling, U., Huang, Y., & Kahn, T. (1990). Sulcus topography of the parietal opercular region: An anatomic and MR study. Brain and Language, 38, 515-533.]). We suggest that certain forms of brain organization may be associated with successful behavioral compensation for dyslexia, and that anatomical variations in the right hemisphere may be important contributors to individual differences in reading acquisition and achievement. 相似文献
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Heldt E Gus Manfro G Kipper L Blaya C Isolan L Otto MW 《Behaviour research and therapy》2006,44(5):657-665
Non-response to pharmacotherapy for panic disorder (PD) is a well-documented problem. However, little information exists to guide next-step strategies for these non-responders. In addition to pharmacologic augmentation strategies, several studies support the efficacy of cognitive-behavior therapy (CBT) for these patients, although data on long-term outcomes has been lacking. In this study, we provide one-year outcomes on a sample of 63 patients who completed group CBT for PD after failing to respond adequately to previous pharmacotherapy. Sustained significant benefit was found for all dimensional outcome scores, and nearly two-thirds of the sample met remission criteria. This occurred with reductions in medication use over the follow-up period. Negative predictors of remission status included comorbid dysthymia, social phobia, and generalized anxiety disorder. These results provide additional evidence for the efficacy of CBT for medication non-responders with PD. 相似文献
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The eye tracks of 29 children (aged 2-7 years) were recorded by a reflection eye camera while they were looking ata4by 4 matrix of 16 white geometric shapes. When a circle suddenly changed to red, the children immediately looked at it for two-thirds of the presentation time, a reading which was 16 times the initial level before this novel color was introduced. With repeated presentations of the novel red circle display, progressively fewer fixations fell on the red circle. After 20 trials, this habituation was incomplete, and the red circle was still drawing six times the initial amount of looking found on the original white circle. Ss were apparently relatively slow to form a neural representation of the visual environment due to the wide range of choices in the original display. The age of the children had no monotonic effect on the high, and virtually equal, initial visual concentration, nor on the rate at which habituation occurred. An interesting contrast, therefore, appeared between these data and the marked age effects noted by others in the recognition of letter-like shapes. Unlike recognition tasks, orienting and habituation need a minimum of stimulus interpretation. Children, even as young as 2 years, have demonstrated a remarkable efficiency in these processes of orienting and habituation to novelty. 相似文献
129.
Otto Neurath 《Erkenntnis》1934,4(1):346-362
Ohne Zusammenfassung
Erwiderung auf Moritz Schlick „über das Fundament der Erkenntnis”, Erkenntnis IV, S. 79, und Thilo Vogel „Bemerkungen zur
Ausfagentheorie des radikalen Phyfikalismus”, Erkenntnis IV, S.160. Bezug wird genommen auf Fred Bon, „Der Gegenftand der Pfychologie”, Erkenntnis IV, S. 363.
Der im folgenden vertretene Standpunkt ift ausführlicher entwickelt in Otto Neurath, „Phyfikalismus”, Scientia 1931, „Soziologie
im Phyfikalismus” (insbefondere: I. Metaphyfikfreier Phyfikalismus, 2. Einheitsfprache des Phyfikalismus), Erkenntnis II,
1931, „Protokollf?tze”, Erkenntnis III, 1932, „Einheitswiffenfchaft und Pfychologie” in Schriftenreihe Einheitswiffenfchaft,
Heft I, Gerold & Co., Wien 1933.
Au?erdem vergleiche man Philipp Frank „Das Kaufalgefetz und feine Grenzen” in Schriften zur Wiffenfchaftlichen Weltauffaffung,
Bd. IV, Julius Springer, Wien 1932, ebenfo die letzten Ver?ffentlichungen Rudolf Carnaps; eine kurze Zufammenfaffung davon
in: „Die Aufgaben der Wiffenfchaftslogik” in Schriftenreihe Einheitswiffenfchaft, Heft III, Gerold & Co., Wien 1934. 相似文献
130.