Behavioral versus Behavioral and Pharmacological Treatment in ADHD Children Attending a Summer Treatment Program

As part of the behavioral treatment in the Multimodal Treatment Study of Children with ADHD (MTA), children participated in an intensive summer treatment program (STP). This study examined the differences between 57 children in the combined treatment (Comb) group, who were medicated, and 60 children in the behavioral treatment (Beh) group, who were unmedicated throughout the STP. Comb children were significantly better than Beh on 5 measures: rule following, good sportsmanship, peer negative nominations, and STP teacher posttreatment ratings of inattention/overactivity. Groups did not differ on any of the other 30 measures, and responded similarly to the STP over time. Comparisons to normative data revealed that Comb children were more likely to fall within the normative range on 6 measures. The differences between these results and the main MTA results, in which Comb was always superior to Beh, are discussed in terms of the relative intensity of combined treatments. The implications for future studies of pharmacological and behavioral treatment for ADHD are discussed.     

New developments in electroconvulsive therapy and magnetic seizure therapy

New findings regarding the mechanisms of action of electro-convulsive therapy (ECT) have led to novel developments in treatment technique to further improve this highly effective treatment for major depression. These new approaches include novel placements, optimization of electrical stimulus parameters, and new methods for inducing more targeted seizures(eg, magnetic seizure therapy [MST]). MST is the use of transcranial magnetic stimulation to induce a seizure. Magnetic fields pass through tissue unimpeded, providing more control over the site and extent of stimulation than can be achieved with ECT. This enhanced control represents a means of focusing the treatment on target cortical structures thought to be essential to antidepressant response and reducing spread to medial temporal regions implicated in the cognitive side effects of ECT. MST is at an early stage of development. Preliminary results suggest that MST may have some advantages over ECT in terms of subjective side effects and acute cognitive functioning. Studies designed to address the antidepressant efficacy of MST are underway. As with all attempts to improve convulsive therapy technique, the clinical value of MST will need to be established through controlled clinical trials. This article reviews the experience to date with MST, and places this work in the broader context of other means of optimizing convulsive therapy in the treatment of depression.     

Dissociations of language function in dementia: A case study

In this report we describe and attempt to characterize the deterioration in semantic knowledge occurring in a victim of a progressive dementing disease. The subject was unable to match even highly familiar naming words with their actual or pictured referents; instead, she consistently overextended verbal labels to closely associated distractors. The alteration in scope of referential meanings suggested by this overextension effect was apparently related to a breakdown in the structure of underlying categories. On a nonverbal match-to-sample procedure, for example, dogs were treated as exemplars of the cat family. Evidence for the breakdown of semantic knowledge was not limited to picture labeling paradigms. Thus, we found that the subject was unable to utilize semantic context in the written disambiguation of spoken homophones but could, at the same time, use even minimal syntactic cues as the basis for proper lexical selection. This last result was consistent with other lines of evidence pointing to the relative preservation of syntactic operations, in marked contrast to the semantic loss. The importance of this dissociation of function in organic pathology is considered from a number of perspectives, including its relevance to models of language organization in the brain.     

Sexual submissiveness in women: costs for sexual autonomy and arousal

Women are bombarded with images of women's sexual submission and subservience to male partners. The authors argue that women internalize this submissive role, namely, they associate sex implicitly with submission. The authors propose that this association leads to submissive sexual behavior, thereby reducing sexual autonomy and arousal. Study 1 found that women implicitly associated sex with submission. Study 2 showed that women's implicit association of sex with submission predicted greater personal adoption of a submissive sexual role. Study 3 found that men did not implicitly associate sex with submission. Study 4 demonstrated that women's adoption of a submissive sexual role predicted lower reported arousal and greater reported difficulty becoming sexually aroused; sexual autonomy mediated these effects.     

Acknowledgments 2002

Dedication

Acknowledgments 2002     

Internalizing Symptoms and Affective Reactivity in Relation to the Severity of Aggression in Clinically Referred,Behavior-Disordered Children

We examined the affective correlates of aggression in children referred to a partial hospitalization program for the treatment of behavior disorders who did not have a mood or anxiety disorder. Parent and teacher ratings of the children’s impulsivity, internalizing symptoms, affective reactivity, and aggression were examined for their interrelationships and then entered into regression analyses to predict the child’s level of aggression in the home, at school, and in the treatment program. Intercorrelations among three affective reactivity factors were modest. Both internalizing symptoms and affective reactivity contributed to aggression severity beyond impulsivity and demographics. Only child irritability predicted treatment program aggression. Because of their potential role in understanding children’s behavioral disturbances, internalizing symptoms and negative emotionality merit careful assessment and treatment in treatment programs serving hard-to-manage children with behavior disorders.     

Glucocorticoid administration into the dorsal striatum [corrected] facilitates memory consolidation of inhibitory avoidance training but not of the context or footshock components

It is well established that glucocorticoid administration into a variety of brain regions facilitates memory consolidation of fear-conditioning tasks, including inhibitory avoidance. The present findings indicate that the natural glucocorticoid corticosterone administered into the dorsal striatum (i.e., caudate nucleus) of male Wistar rats produced dose- and time-dependent enhancement of inhibitory avoidance memory consolidation. However, as assessed with a modified inhibitory avoidance procedure that took place on two sequential days to separate context training from footshock training, corticosterone administration into the dorsal striatum did not enhance memory of either the contextual or aversively motivational aspects of the task.     

Predictive Factors of Spiritual Quality of Life during the COVID-19 Pandemic: A Multivariate Analysis

Journal of Religion and Health - COVID-19 has led to the implementation of various social and sanitary measures, impacting populations’ quality of life. Aims: Documenting the spiritual...     

Adult outcomes as a function of an early childhood educational program: an Abecedarian Project follow-up

Adult (age 30) educational, economic, and social-emotional adjustment outcomes were investigated for participants in the Abecedarian Project, a randomized controlled trial of early childhood education for children from low-income families. Of the original 111 infants enrolled (98% African American), 101 took part in the age 30 follow-up. Primary indicators of educational level, economic status, and social adjustment were examined as a function of early childhood treatment. Treated individuals attained significantly more years of education, but income-to-needs ratios and criminal involvement did not vary significantly as a function of early treatment. A number of other indicators were described for each domain. Overall, the findings provide strong evidence for educational benefits, mixed evidence for economic benefits, and little evidence for treatment-related social adjustment outcomes. Implications for public policy are discussed.     

Zuckerman-Kuhlman-Aluja Personality Questionnaire (ZKA-PQ) and Cloninger's Temperament and Character Inventory Revised (TCI-R): a comparative study

The aim of this study was to compare the psychometric properties (normal distribution values, reliabilities and factor structure) of the Zuckerman-Kuhlman-Aluja Personality Questionnaire (ZKA-PQ) and the Temperament and Character Inventory revised (TCI-R). The total sample consisted of 482 subjects (53.1% men and 46.9% women) from diverse age. Results showed somewhat better psychometric properties, like reliability and facet-factor structure, for the ZKA-PQ than the TCI-R. The expected five-factor facet structure of the ZKA-PQ was clear found. However, the seven-factor structure of TCI-R was not clear and it did not show a clear distinction between Temperament and Character factors. When ZKA-PQ and TCI-R variables are analyzed together, the ZKA-PQ factors are related to the Character as well as the Temperament factors. In some cases they represent the opposite poles of ZKA-PQ factors; for example, Neuroticism versus Self-Directiveness and Aggression versus Cooperativeness. Some are directly and highly related to ZKA-PQ factors; for example, Sensation Seeking and Novelty Seeking, Extraversion and Reward Dependence, Neuroticism and Harm Avoidance, and Activity and Persistence.