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71.
G Gallegos L Salazar M Ortiz W Marquez A Davis S Sanchez D Conner H L Schreiber 《Behavioral and neural biology》1990,53(2):172-188
Three experiments were performed to determine whether apparently minimal disturbances of dams and litters would influence haloperidol-induced akinesia. In Experiment I, Long-Evans hooded rats (a) were left unmanipulated, (b) received nestcage relocation and observation, (c) received nestcage relocation/observation and maternal separation, or (d) received nestcage relocation/observation and pup handling. The male adult offspring received open-field testing and later received forepaw-on-dowel catalepsy testing following saline, morphine (20 mg/kg), or haloperidol (2 mg/kg). In Experiment II, hooded rats received (a) no manipulation, (b) nestcage relocation, (c) maternal separation, or (d) pup handling. At weaning, dams were tested in the open-field. Activity wheel locomotion of the offspring was assessed following saline or haloperidol for 3 days/week for 3 weeks; then, 5 and 7 days later, rats received haloperidol (0.5 mg/kg) and catalepsy testing. In both experiments, manipulations involving the dam reduced the offsprings' haloperidol-induced catalepsy, but, in Experiment II, a history of haloperidol administration distinguished between the effects of nestcage relocation and maternal separation. In Experiment III, Swiss albino mice received (a) no treatment, (b) nestcage relocation and maternal separation, (c) relocation/separation and mild cold stress of pups, (d) relocation/separation and pup handling, or (e) relocation/separation and severe cold stress of pups. Adult male mice received saline or haloperidol (2.5 mg/kg) and inclined grid catalepsy testing. Mice receiving relocation/separation and mice receiving relocation/separation and severe cold stress showed enhanced catalepsy versus control mice. Thus, it was concluded that seemingly innocuous events in infancy can influence the intensity of extrapyramidal side effects of neuroleptics in adulthood. 相似文献
72.
Torres Ortiz Sara Corregidor Castro Alejandro Balsby Thorsten Johannes Skovbjerg Larsen Ole Næsbye 《Animal cognition》2020,23(2):265-275
Animal Cognition - Cooperation is a complex behaviour found in many kinds of organisms and occurs between individuals of the same and different species. Several studies have examined the... 相似文献
73.
Jaziel Ramos‐Ortiz Stephanie Meier Melissa Rossi Heather Heyrman Megha Reddy Andrea L. DeMaria 《Journal of Consumer Behaviour》2020,19(5):399-408
The La Bella Figura concept extends to many Italian cultural dimensions including physical appearance, perception of self, and behaviours. La Bella Figura plays an essential role in shaping Italian consumer behaviour and consumerism. The current study sought to understand how women living in Italy conceptualize La Bella Figura and how it affects their day‐to‐day lives, attitudes, and consumption behaviours. This research extracted concepts from Consumer Culture Theory to construct a qualitative codebook and structure thematic data analyses. Semi‐structured interviews were conducted with 30 women aged 18–50 years living in Florence, Italy. Participants were recruited through study flyers, social media, and snowball sampling. Open and axial coding were facilitated by HyperRESEARCH 4.0.1 software to generate key themes. Data were collected and analyzed by trained researchers living in Florence, Italy, who utilized grounded theory techniques to identify emergent themes. Results indicated various components of La Bella Figura contributed to consumer behaviour, namely its influence on identity (i.e., appearance, confidence), lifestyle goals (i.e., health, consumerism), and social norms (i.e., perceptions of others, media). Findings offer practical recommendations for marketers and retailers to appeal to the Italian market through effective and informed mediums. 相似文献
74.
The experiments were performed on adult male cats selected initially as good mousekillers. Cats were tested in pairs and each pair was introduced separately to the experimental compartment. The attitude toward the partner before and during the predatory competition test as well as superiority in catching and killing the mice, considered as an index of dominance, were registered. In the course of experiment five types of relations between the predatory dominance and aggressive behavior were observed. The concept of dominance as an outcome of several factors was discussed. It was concluded that predatory dominance is not based exclusively on aggressive mechanisms, as it may be formed and sustained without overt aggression. 相似文献
75.
76.
This article examines the usefulness of the Family Assessment Device(FAD) in assessing family functioning with school-aged children (under 12 years of age) compared to children 12 and older and mothers. FAD reports from 194 children with asthma (132 under 12 years; 62 12 years and older) were evaluated in comparison to mothers' FAD reports as well as mothers' reports on two other family functioning measures: the Family Inventory of Life Events (FILE) and the Impact on Family (IOF) scale, both relevant to functioning in families with children with asthma. Although FAD scale reliabilities were lowest in younger children (alpha = 48-.79), good concurrent validity was found with mothers' reports on the three different measures of family functioning. Older childrens' FAD scales showed good reliability (> .70) but poorer agreement with the various maternal measures. With modifications to make items more structured and simplified, the FAD could be tried with younger children, although documentation of improved reliability is needed before more widespread use with school-aged children is advocated. The measure already shows good agreement with maternal report in this younger age group, which likely would be strengthened with improved reliability. FAD reports in older children correlated less well with maternal measures, but may represent nonredundant information on family health from an independent perspective and are worth considering in addition to mothers' perspectives. 相似文献
77.
Working and long-term memory deficits in schizophrenia: is there a common prefrontal mechanism? 总被引:3,自引:0,他引:3
This study tested the hypothesis that dorsolateral prefrontal cortex deficits contribute to both working memory and long-term memory disturbances in schizophrenia. It also examined whether such deficits were more severe for verbal than nonverbal stimuli. Functional magnetic resonance imaging was used to assess cortical activation during performance of verbal and nonverbal versions of a working memory task and both encoding and recognition tasks in 38 individuals with schizophrenia and 48 healthy controls. Performance of both working memory and long-term memory tasks revealed disturbed dorsolateral prefrontal cortex activation in schizophrenia, although medial temporal deficits were also present. Some evidence was found for more severe cognitive and functional deficits with verbal than nonverbal stimuli, although these results were mixed. 相似文献
78.
The goal of this study was to test the response styles theory of depression in a sample of 3rd- and 7th-grade children. In addition, we examined whether the relationship between rumination and increases in depressive symptoms is mediated by hopelessness and low self-esteem. The procedure involved an initial assessment in which depressive symptoms, response styles, hopelessness, and self-esteem were assessed. The procedure also involved a follow-up assessment, 6 weeks later, in which depressive symptoms, hopelessness, and self-esteem were reassessed. Children with a ruminative response style exhibited increases in depressive symptoms over the 6-week period. In addition, the relationship between rumination and increases in depressive symptoms was mediated by both hopelessness and low self-esteem. Last, contrary to our hypotheses, neither distraction nor problem-solving response styles predicted decreases in depressive symptoms over the course of the study. 相似文献
79.
George MS Nahas Z Bohning DE Lomarev M Denslow S Osenbach R Ballenger JC 《CNS spectrums》2000,5(11):43-52
Although the vagus nerve has traditionally been considered to perform efferent functions, in reality it performs significant afferent functions as well, carrying information from the body, head, and neck to the brain. Preliminary studies examining this afferent activity led to the theory that vagus nerve stimulation (VNS) could successfully control seizure activity in persons who are refractory to antiepileptic medications. Unlike other forms of brain stimulation, VNS is unable to directly stimulate multiple discrete areas of the brain; however, through several pathways, it is able to relay sensory information to higher brain regions. An implantable VNS device known as the VNSTM NeuroCybernetic Prosthesis (NCP) System has been used in approximately 9,000 epilepsy patients in Europe and the United States since 1994. The implant has reduced seizure frequency by an average of 25% to 30%, with minimal side effects. Studies underway are also showing some degree of success in the management of treatment-refractory depression. The future efficacy of the implantable system in other disorders may depend on whether the implant can be more precisely focused to affect different brain regions. Research in this area is underway. 相似文献
80.
Mean response times, variability, and skew in the responding of ADHD children: a response time distributional approach 总被引:7,自引:0,他引:7
Response time (RT) distributions from three fixed foreperiod conditions (2, 4, and 8 s) in a warned four-choice RT task were obtained for a group of boys with attention-deficit/hyperactivity disorder, combined type (ADHD; n = 17) and for two groups of normal control boys (age-matched, n = 18, and younger-aged, n = 10). Quantitative measures of distributional shape were derived by fitting the ex-Gaussian distributional model to the individual RT data. Statistical results indicate that the ADHD distributions differ from the age-matched control distributions with respect to the size of the tail (larger for the ADHD boys), but differ from the younger control distributions with respect to the location of the leading edge (slower for the younger control boys). Receiver operating characteristic (ROC) results reveal that the ex-Gaussian exponential component is highly diagnostic of the ADHD boys. 相似文献