Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children. We tested whether patterns of brain growth, cognitive deficits and white matter hyperintensities (WMH) are associated with exposures to severe air pollution. Baseline and 1 year follow-up measurements of global and regional brain MRI volumes, cognitive abilities (Wechsler Intelligence Scale for Children-Revised, WISC-R), and serum inflammatory mediators were collected in 20 Mexico City (MC) children (10 with white matter hyperintensities, WMH⁺, and 10 without, WMH⁻) and 10 matched controls (CTL) from a low polluted city. There were significant differences in white matter volumes between CTL and MC children - both WMH⁺ and WMH⁻ - in right parietal and bilateral temporal areas. Both WMH⁻ and WMH⁺ MC children showed progressive deficits, compared to CTL children, on the WISC-R Vocabulary and Digit Span subtests. The cognitive deficits in highly exposed children match the localization of the volumetric differences detected over the 1 year follow-up, since the deficits observed are consistent with impairment of parietal and temporal lobe functions. Regardless of the presence of prefrontal WMH, Mexico City children performed more poorly across a variety of cognitive tests, compared to CTL children, thus WMH⁺ is likely only partially identifying underlying white matter pathology. Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood.     

Insufficient Referral for Genetic Counseling in the Management of Hereditary Haemochromatosis in Portugal: A Study of Perceptions of Health Professionals Requesting HFE Genotyping

There is a general consensus that HFE- related Hereditary Haemochromatosis (HFE-HH) should be diagnosed at early stages in pre-symptomatic individuals, in order to prevent the most severe consequences of iron overload. In Portugal, despite an increasing number of requests for genetic diagnosis of this rare disease, there is not a corresponding increase in requests for genetic counselling. The objective of the present study was to evaluate physicians’ main motivations for requesting HFE genotyping or genetic counselling for HFE-HH. We assessed current medical practices regarding family testing and diagnosis and discuss whether these can be improved in order to increase the effectiveness of disease prevention. Our results show there is a general lack of knowledge about the selection of patient cases that should be sent for genetic counseling or for molecular testing of HFE-HH by physicians (especially by general practitioners). The lack of family-based screening may indirectly compromise the efficiency of disease prevention in terms of early diagnosis and treatment. We concluded it is necessary to circulate more information about Hereditary Haemochromatosis among health professionals in order to improve strategies for its early diagnosis.     

The Role Maturity of Parents of Emerging Adult Children: Validity of a Parental Maturity Measure

Parental maturity refers to parents’ ability to see their child as an independent adult with limitations and needs, and relate to him/her accordingly. In this study, we had two main aims: (a) develop a measure of parental maturity and test its construct validity in a sample of middle-aged parents with an emerging adult child, and (b) examine how the dimensions of parental maturity varied with a child’s gender and life course transitions (i.e., employment and leaving the parental home). A sample of 343 Portuguese parents (187 mothers and 156 fathers) aged 40–68 participated in this study. Factorial validity of the Parental Maturity Measure was tested using exploratory and confirmatory factor analyses and measurement invariance across mothers and fathers. Results gave support for a two-factor measure—Comprehending (6 items) and Letting Go (4 items)—with an equivalent meaning across parents. Dimensions of parental maturity were associated with differentiated and positive parent–child relationship qualities, but were quite independent of the child’s gender and life course transitions.     

Mind the ad: How personality requirements affect older and younger job seekers' job attraction

Age discrimination may explain lower labour market chances of older and younger job seekers. What remains underresearched, however, is how older/younger job seekers might self-select out from early recruitment procedures due to stigmatizing information in job ads. Building on theories of metastereotypes and the linguistic category model, two experimental studies investigated how personality requirements that older/younger job seekers hold negative metastereotypes about and the way in which these requirements are worded (behavioural vs. dispositional) affected their job attraction. Within-participant mediation analyses showed that as expected, job attraction was higher for older (N = 123, aged 50 years or more) and younger (N = 151, 30 years or less) job seekers when requirements were worded in a behavioural way (e.g., ‘You can be flexible’), compared with a dispositional way (e.g., ‘You are flexible’). This relation was mediated by perceptions of challenge among younger but not older job seekers. Contrary to expectations, perceptions of threat did not explain the effects of negatively metastereotyped personality requirements on job attraction. Understanding how job seekers perceive information in job ads might help recruiters to design age-sensitive recruitment policies.     

Social Contact,Academic Satisfaction,COVID-19 Knowledge,and Subjective Well-being Among Students at Turkish Universities: a Nine-University Sample

Adverse effects of COVID-19 are seen not only on the physical health of infected individuals but also on their subjective well-being. Sudden changes in social lives, lockdowns, and shifts towards online education have had a negative impact on many people, especially university students. As part of an international study, the current study focused on the well-being of students at Turkish universities in relation to social contact, academic satisfaction, and COVID-19 knowledge. A total of 7363 students from nine universities (86.6% from state universities, 71.04% female, and 73.52% at bachelor’s level) participated in an online survey. Results revealed that females had lower levels of subjective well-being and academic satisfaction. According to a mediation model in the study, the relationship between social contact and well-being was mediated by academic satisfaction and COVID-19 knowledge. Our findings can guide future researchers, mental health professionals, universities, and policymakers to understand and improve subjective well-being of university students.

     

How normative and social identification processes predict self‐determination to engage in derogatory behaviours against outgroup hockey fans

Bringing together self‐determination theory, intergroup theories based on the social identity approach, and normative approaches, three studies conducted among hockey fans tested if social norms and social identity predict greater self‐determined motivation to engage in derogatory behaviours against an outgroup team and higher frequency of these behaviours. Higher self‐determination was conceptualised as an indicator of internalisation. In Study 1, hockey fans who identified more strongly as fans of the Montreal Canadiens (N = 181) displayed a stronger positive association between the perceived norm in favour of outgroup derogation and self‐determined motivation to engage in derogatory behaviours against fans of an outgroup team. This interaction also emerged on the frequency with which the derogatory behaviours were enacted. In Studies 2 and 3 (Ns = 105 and 116), this norm by social identity interaction was replicated on both the self‐determination and the frequency outcomes for fans of a diversity of teams in the National Hockey League. In Study 3, these findings were observed over and above a manipulation that framed derogatory behaviours as being either harmful or beneficial. Results are discussed in light of motivational theories, normative approaches, and intergroup theories based on the social identity approach. Copyright © 2014 John Wiley & Sons, Ltd.     

Attachment,Infidelity, and Loneliness in College Students Involved in a Romantic Relationship: The Role of Relationship Satisfaction,Morbidity, and Prayer for Partner

This study examined the mediating effects of relationship satisfaction, prayer for a partner, and morbidity in the relationship between attachment and loneliness, infidelity and loneliness, and psychological morbidity and loneliness, in college students involved in a romantic relationship. Participants were students in an introductory course on family development. This study examined only students (n = 345) who were involved in a romantic relationship. The average age of participants was 19.46 (SD = 1.92) and 25 % were males. Short-form UCLA Loneliness Scale (ULS-8), (Hays and DiMatteo in J Pers Assess 51:69–81, doi:10.1207/s15327752jpa5101_6, 1987); Relationship Satisfaction Scale (Funk and Rogge in J Fam Psychol 21:572–583, doi:10.1037/0893-3200.21.4.572, 2007); Rotterdam Symptom Checklist (De Haes et al. in Measuring the quality of life of cancer patients with the Rotterdam Symptom Checklist (RSCL): a manual, Northern Centre for Healthcare Research, Groningen, 1996); Prayer for Partner Scale, (Fincham et al. in J Pers Soc Psychol 99:649–659, doi:10.1037/a0019628, 2010); Infidelity Scale, (Drigotas et al. in J Pers Soc Psychol 77:509–524, doi:10.1037/0022-3514.77.3.509, 1999); and the Experiences in Close Relationship Scale-short form (Wei et al. in J Couns Psychol 52(4):602–614, doi:10.1037/0022-0167.52.4.602, 2005). Results showed that relationship satisfaction mediated the relationship between avoidance attachment and loneliness and between infidelity and loneliness. Physical morbidity mediated the relationship between anxious attachment and psychological morbidity. Psychological morbidity mediated the relationship between anxious attachment and physical morbidity. The present results expand the literature on attachment by presenting evidence that anxious and avoidant partners experience loneliness differently. Implications for couple’s therapy are addressed. Future research should replicate these results with older samples and married couples.     

Eye movements disrupt spatial but not visual mental imagery

It has long been known that eye movements are functionally involved in the generation and maintenance of mental images. Indeed, a number of studies demonstrated that voluntary eye movements interfere with mental imagery tasks (e.g., Laeng and Teodorescu in Cogn Sci 26:207–231, 2002). However, mental imagery is conceived as a multifarious cognitive function with at least two components, a spatial component and a visual component. The present study investigated the question of whether eye movements disrupt mental imagery in general or only its spatial component. We present data on healthy young adults, who performed visual and spatial imagery tasks concurrently with a smooth pursuit. In line with previous literature, results revealed that eye movements had a strong disruptive effect on spatial imagery. Moreover, we crucially demonstrated that eye movements had no disruptive effect when participants visualized the depictive aspects of an object. Therefore, we suggest that eye movements serve to a greater extent the spatial than the visual component of mental imagery.     

The update of semantic memories in amnestic mild cognitive impairment

It is still controversial to what extent neocortical consolidated memories are susceptible of change by processes of reconsolidation and transformation throughout experience, and whether the medial temporal lobes are necessary for this update of semantic consolidated memories, as they are for episodic remembering. We hypothesize that patients with amnestic mild cognitive impairment (aMCI) who have deficits in episodic memory may also have difficulties in updating information on added new features of objects. Sixteen participants with aMCI and 20 healthy control participants performed a semantic word-to-picture task, in which they were asked to identify as belonging to a given semantic category NEW objects, that have incorporated novel features, as well as OLD items, semantically and visually SIMILAR items and UNRELATED items. Patients with aMCI made a greater percentage of errors than healthy controls. Participants globally made greater percentages of errors in difficult types of items, namely NEW and SIMILAR, as compared to easier ones, OLD and UNRELATED. Importantly, an item by diagnostic group interaction effect was observed, and post hoc analysis showed that patients with aMCI made a higher percentage of errors than controls in NEW items only. In conclusion, patients with aMCI had a particular difficulty in identifying the NEW items of the word-to-picture task as compared to the control participants, supporting the concept of a flexible and dynamic conceptual knowledge system, involving the update of semantic memories and the integration of new attributes in a constant transformation process, which is impaired in these patients.