Enriched housing reverses age-associated impairment of cognitive functions and tPA-dependent maturation of BDNF

Although tissue type plasminogen activator (tPA) and brain derived neurotrophic factor (BDNF) have been extensively described to influence brain outcomes in a number of disorders, their roles during physiological aging are poorly investigated. In the present study, we investigated whether maintenance of mice in different environmental conditions could influence age-associated changes in hippocampal tPA expression and BDNF maturation in relation with modifications of their cognitive performances. Our data indicate that maintenance in enriched housing led to a reversal of age-associated decrease in expression of hippocampal tPA. A subsequent increase in the level of mature BDNF and an improvement in emotional and spatial memories were observed. Taken together, these data suggest that the tPA–BDNF axis could play a critical role in the control of cognitive functions influenced both by the age and housing conditions.     

N-backer: an auditory n-back task with automatic scoring of spoken responses

The n-back task is commonly used to load working memory (WM) in dual-task and neuroimaging experiments. However, it typically involves visual presentation and buttonpress responses, making it unsuitable for combination with primary tasks that involve vision and action, such as sequential object use and other tasks of daily living. The N-backer software presented here will automatically present and score auditory–verbal n-back sequences utilising the standard speech synthesis and recognition facilities that come with Microsoft Windows. Data are presented from an experiment in which 12 student participants carried out three tasks from the Naturalistic Action Test (NAT) while their attention was divided between the primary task and a continuous auditory–verbal 2-back secondary task. The participants’ 2-back performance was scored in two ways: by hand, from video recordings, and automatically, using the software, allowing us to evaluate the accuracy of N-backer. There was an extremely high correlation between these scores (.933). The videos were also used to obtain a comprehensive error score for the NAT. Significantly more errors were made in the more complex NAT tasks when participants were 2-backing, as compared with when they were not, showing that the auditory–verbal n-back task can be used to disrupt sequential object use. This dual-task method may simulate the attentional deficits of patients with brain injury, providing insights into the difficulties they face in tasks of daily living.     

On reducing an empathy gap: the impact of self-construal and order of judgment

Empathy gaps, in which individuals exaggerate self-other similarities or differences, generate errors in social judgments. We investigated whether changing individuals' self-construal may reduce one specific empathy gap: the illusion of courage. Participants primed with independent or interdependent self-construal made judgments about their own and other people's willingness to dance in public. Participants in the interdependence condition showed a reduction of the empathy gap, but only when judging the other first. This finding highlights that simple contextual manipulations have the potential to reduce egocentric biases in social judgments.     

Attentional bias in post-traumatic stress disorder diminishes after symptom amelioration

Background

Avoidance and hypervigilance to reminders of a traumatic event are among the main characteristics of post-traumatic stress disorder (PTSD). Attentional bias toward aversive cues in PTSD has been hypothesized as being part of the dysfunction causing etiology and maintenance of PTSD. The aim of the present study was to investigate the cognitive strategy underlying attentional bias in PTSD and whether normal cognitive processing is restored after a treatment suppressing core PTSD symptoms.

Methods

Nineteen healthy controls were matched for age, sex and education to 19 PTSD patients. We used the emotional stroop and detection of target tasks, before and after an average of 4.1 sessions of eye movement desensitization and reprocessing (EMDR) therapy.

Results

We found that on both tasks, patients were slower than controls in responding in the presence of emotionally negative words compared to neutral ones. After symptoms removal, patients no longer had attentional bias, and responded similarly to controls.

Conclusion

These results support the existence of an attentional bias in PTSD patients due to a disengagement difficulty. There was also preliminary evidence that the disengagement was linked to PTSD symptomatology. It should be further explored whether attentional bias and PTSD involve common brain mechanisms.     

Preschoolers are able to take merit into account when distributing goods

Classic studies in developmental psychology demonstrate a relatively late development of equity, with children as old as 6 or even 8-10 years failing to follow the logic of merit--that is, giving more to those who contributed more. Following Piaget (1932), these studies have been taken to indicate that judgments of justice develop slowly and follow a stagelike progression, starting off with simple rules (e.g., equality: everyone receives the same) and only later on in development evolving into more complex ones (e.g., equity: distributions match contributions). Here, we report 2 experiments with 3- and 4-year-old children (N = 195) that contradict this constructivist account. Our results demonstrate that children as young as 3 years old are able to take merit into account by distributing tokens according to individual contributions but that this ability may be hidden by a preference for equality.     

Positive emotional context eliminates the framing effect in decision-making

Dual-process theories have suggested that emotion plays a key role in the framing effect in decision-making. However, little is known about the potential impact of a specific positive or negative emotional context on this bias. We investigated this question with adult participants using an emotional priming paradigm. First, participants were presented with positive or negative affective pictures (i.e., pleasant vs. unpleasant photographs). Afterward, participants had to perform a financial decision-making task that was unrelated to the pictures previously presented. The results revealed that the presentation framed in terms of gain or loss no longer affected subjects' decision-making following specific exposure to emotionally pleasant pictures. Interestingly, a positive emotional context did not globally influence risk-taking behavior but specifically decreased the risk propensity in the loss frame. This finding confirmed that a positive emotional context can reduce loss aversion, and it strongly reinforced the dual-process view that the framing effect stems from an affective heuristic belonging to intuitive System 1. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

A new "fat face" illusion

We report a novel fat face illusion that when two identical images of the same face are aligned vertically, the face at the bottom appears 'fatter'. This illusion emerged when the faces were shown upright, but not inverted, with the size of the illusion being 4%. When the faces were presented upside down, the illusion did not emerge. Also, when upright clocks were shown in the same vertically aligned fashion, we did not observe the illusion, indicating that the fat illusion does not generalize to every category of canonically upright objects with similar geometric shape as a face.     

Inclusion practices with Special Educational Needs students in a Hong Kong secondary school: teachers’ narratives from a school guidance perspective

Schools in Hong Kong are concerned about the growing enrolments of students with special educational needs (SEN) and how these students could be included in school guidance. This study examines teachers’ narratives of the inclusivity of school guidance. The study was qualitative, being a case study of a Hong Kong secondary school. School documents were collected for textual analysis and semi-structured interviews with 13 teachers were conducted, including nine guidance teachers and four other teachers who worked closely with these guidance teachers. Four dimensions for the inclusivity of school guidance were identified: the development of inclusive practices of guidance, the adoption of a proactive approach, the promotion of inclusive discipline, and the clear definition of the partnership between school guidance and professional organization offering specialised services for students with SEN. The study provides insights into contextual influences of Hong Kong education on school guidance and the development of an inclusive approach to guidance.     

Mood effects on dominated choices: Positive mood induces departures from logical rules

In two studies, we investigated the role of mood states in dominated behavioral choices. Past research has shown that mood effects on judgment and decision‐making can be pervasive. Yet, the role of mood in dominated choices has so far been neglected. The present research represents a first empirical examination of mood effects on dominated choices. We measured (Study 1) or manipulated (Study 2) mood states in participants who made a series of choices in a gambling game. In this choice task without trade‐offs, participants were provided with information about the outcomes and probabilities associated with each choice option. The strategy to maximize the expected mean outcome implied the application of a straightforward and logical rule: Always choose the dominant option with the highest expected value. It has been argued in the literature that mood should have little or no impact when preferences are clear or strong. Still, we expected that mood states would affect even these dominated choices, building on previous work that showed that positive mood states enhance flexibility, creativity, and explorative behavior. The results showed that decisions made in a happier mood were less often in accordance with the logical rule than decisions made in a sadder mood. To conclude, happier mood states are associated to a lesser extent with decisions in accordance with a rule‐based strategy that maximizes expected mean outcomes in dominated choices. Copyright © 2010 John Wiley & Sons, Ltd.     

Attention-Deficit Hyperactivity Disorder Symptoms and Entrepreneurial Orientation: A Replication Note

There is a small body of literature linking attention-deficit hyperactivity disorder (ADHD) and its symptoms to entrepreneurial manifestations. Some studies take a subclinical perspective by studying the presence of symptoms, while other studies take a clinical perspective by studying the formal diagnosis of ADHD. The entrepreneurial manifestations examined range from entrepreneurial intention to the choice to become self-employed and from entrepreneurial orientation (EO) to entrepreneurial success. Despite its prominence in the entrepreneurship literature, to date only one study tested for a link with EO. The present study aims to replicate the relationship between ADHD symptoms and EO using a large data set of French small business owners. We do so by discriminating between the two dimensions of ADHD, namely attention-deficit and hyperactivity, as well as the three dimensions of EO, namely innovativeness, proactiveness, and risk-taking. We do not find a link between ADHD and EO, although we do find a positive link between ADHD and the risk-taking subdimension of EO. Hyperactivity symptoms are positively related to EO, which is mainly driven by the subdimensions proactiveness and risk-taking. We do not find a link between attention-deficit symptoms and EO, though there is a negative link between attention-deficit and proactiveness.