Zinc transporter 3 is involved in learned fear and extinction, but not in innate fear

Synaptically released Zn2+ is a potential modulator of neurotransmission and synaptic plasticity in fear-conditioning pathways. Zinc transporter 3 (ZnT3) knock-out (KO) mice are well suited to test the role of zinc in learned fear, because ZnT3 is colocalized with synaptic zinc, responsible for its transport to synaptic vesicles, highly enriched in the amygdala-associated neural circuitry, and ZnT3 KO mice lack Zn2+ in synaptic vesicles. However, earlier work reported no deficiency in fear memory in ZnT3 KO mice, which is surprising based on the effects of Zn2+ on amygdala synaptic plasticity. We therefore reexamined ZnT3 KO mice in various tasks for learned and innate fear. The mutants were deficient in a weak fear-conditioning protocol using single tone-shock pairing but showed normal memory when a stronger, five-pairing protocol was used. ZnT3 KO mice were deficient in memory when a tone was presented as complex auditory information in a discontinuous fashion. Moreover, ZnT3 KO mice showed abnormality in trace fear conditioning and in fear extinction. By contrast, ZnT3 KO mice had normal anxiety. Thus, ZnT3 is involved in associative fear memory and extinction, but not in innate fear, consistent with the role of synaptic zinc in amygdala synaptic plasticity.     

Comparative Optimism and Event Skewness

Comparative judgment biases—wherein a majority of people report being above‐ or below‐average in their abilities, traits, or future events—are a robust phenomenon in psychology. A recent explanation for these biases has focused on people's awareness that many comparative judgment domains form skewed distributions, and, hence, a majority of people can feasibly be above or below average. Indeed, this prior research found that comparative biases for abilities emerged more for skewed (vs. normal) distributions. In the current research, we attempted to (i) conceptually replicate this finding in a comparative likelihood context and (ii) provide evidence of an alternative explanation for the prior results. Replicating prior research, three correlational studies and one experimental study found that event skewness was related to direct comparative likelihood judgments for health events, such that comparative optimism emerged more for events judged or manipulated to come from positively skewed distributions than from negatively skewed distributions. However, event skewness was unrelated to indirect comparisons (absolute self minus absolute other). Moreover, consistent with an egocentric‐processes account, absolute self‐judgments were more predictive of direct comparisons than were absolute other judgments and showed the same association with event skewness as direct comparisons. Implications for explaining and interpreting comparative judgment biases are discussed. Copyright © 2016 John Wiley & Sons, Ltd.     

The visual perception of distance ratios outdoors

We conducted an experiment to evaluate the ability of 32 younger and older adults to visually perceive distances in an outdoor setting. On any given trial, the observers viewed 2 environmental distances and were required to estimate the distance ratio—the length of the (usually) larger distance relative to that of the shorter. The stimulus distance ratios ranged from 1.0 (the stimulus distances were identical) to 8.0 (1 distance interval was 8.0 times longer than the other). The stimulus distances were presented within a 26 m × 60 m portion of a grassy field. The observers were able to reliably estimate the stimulus distance ratios: The overall Pearson r correlation coefficient relating the judged and actual distance ratios was 0.762. Fifty-eight percent of the variance in the observers’ perceived distance ratios could thus be accounted for by variations in the actual stimulus ratios. About half of the observers significantly underestimated the distance ratios, while the judgments of the remainder were essentially accurate. Significant modulatory effects of sex and age occurred, such that the male observers’ judgments were the most precise, while those of the older males were the most accurate.     

Art-Making and its Interface With Dissociative Identity Disorder: No Words That Didn’t fit

Studies point to promising developments in expressive arts therapy work with clients who experience dissociation as one of a constellation of symptoms of trauma. Individuals diagnosed with Dissociative Identity Disorder, however, may be hesitant to engage with long-term therapy and its relationship. This article presents the case of one such individual, a participant in a narrative phenomenological study who was able to develop her own visual art-making practice. Reflections on this practice revealed that it offered a safe place for her to explore the voice of her “parts” hitherto silenced. Her narrative has implications for professionals working in the expressive and talking therapies.     

Leibniz's non-tensed theory of time

Leibniz's philosophy of time, often seen as a precursor to current forms of relationalism and causal theories of time, has rightly earned the admiration of his more recent counterparts in the philosophy of science. In this article, I examine Leibniz's philosophy of time from a new perspective: the role that tense and non-tensed temporal properties/relations play in it. Specifically, I argue that Leibniz's philosophy of time is best (and non-anachronistically) construed as a non-tensed theory of time, one that dispenses with tensed temporal properties such as past, present, and future. In arguing for this thesis, I focus on the three facets of Leibniz's philosophy most relevant for evaluating his commitment to a B-theory of time: (1) the nature of change, (2) the reality of the future, and (3) the truth-conditions for tensed temporal statements. Despite prima facie evidence to the contrary, I show that a close examination of Leibniz's views on these topics provides compelling evidence for interpreting his philosophy of time as a B-theory of time.     

Therapeutic implications of counselling psychologists’ responses to client trauma: An interpretative phenomenological analysis

The past two decades have seen a surge of interest in the impact of working with trauma survivors on therapists’ psychological well-being. Existing literature assumes that therapists’ strong subjective responses to traumatic material adversely influence the therapeutic process. However, this has not yet been directly researched. Nine counselling psychologists were interviewed regarding the clinical impact of their responses to the disclosure of traumatic material. Interpretative Phenomenological Analysis showed that significant challenges are experienced in the use of self in therapy with trauma survivors, including making sense of horrific human actions, negotiating complex interpersonal dynamics and responding to ethical dilemmas in therapy. Results emphasised the importance that therapists attached to the development of their therapeutic use of self in therapy with trauma survivors, the value of learning from others and reaching a place of acceptance and hope when working with trauma survivors. Finally, specific training and development implications are proposed.     

Exploring the role,needs and challenges of relatives of mothers with HIV or HIV and psychosis: A qualitative study

This study explored types and nature of supports by relatives of mothers living with HIV and psychosis in comparison to mothers with HIV only. Interview data on their experiences of their roles, needs and challenges were collected from 33 relatives on mothers with HIV and psychosis (n=12, females=10, blacks =12, age ranges 21 to 62) and those with HIV only (n=21, females=16, blacks =21, age ranges 18 to 63). The data were thematically analysed utilizing Atlas.ti. The results showed that relatives in both groups provided a variety of supporting roles. Important challenges were experiencing the negative consequences of especially HIV in combination with psychosis in their lives and dealing with the caregiving responsibilities without having enough information. Important strengths included utilizing support networks and remaining hopeful. Support needs for carers of mothers living with HIV related psychosis or HIV only, can be enhanced with increasing social and material resources at the community level. Supporting needs can be addressed by empowering communities through psycho-education.     

A survey of residual analysis and a new test of residual trend

A survey of residual analysis in behavior‐analytic research reveals that existing methods are problematic in one way or another. A new test for residual trends is proposed that avoids the problematic features of the existing methods. It entails fitting cubic polynomials to sets of residuals and comparing their effect sizes to those that would be expected if the sets of residuals were random. To this end, sampling distributions of effect sizes for fits of a cubic polynomial to random data were obtained by generating sets of random standardized residuals of various sizes, n. A cubic polynomial was then fitted to each set of residuals and its effect size was calculated. This yielded a sampling distribution of effect sizes for each n. To test for a residual trend in experimental data, the median effect size of cubic‐polynomial fits to sets of experimental residuals can be compared to the median of the corresponding sampling distribution of effect sizes for random residuals using a sign test. An example from the literature, which entailed comparing mathematical and computational models of continuous choice, is used to illustrate the utility of the test.