Impact of outpatient non-myeloablative haematopoietic stem cell transplantation in quality of life vs. conventional therapy

The role of outpatient hematopoietic stem cell transplantation (HSCT) as a therapeutic tool has been strengthened significantly because of the increasing number of patients undergoing this treatment. Due the very nature of this procedure, one of the aspects that should not be overlooked is the quality of life (QOL) of patients undergoing HSCT. Thus, one must consider not only health status after treatment, but also, the psychosocial implications for the patient. This is an observational, longitudinal, and prospective study to assess QOL in patients undergoing outpatient HSCT vs. similar patients receiving medical treatment (MxTx). By applying the COOP/WONKA charts on five occasions (pre-HSCT/initial, post-HSCT/first month, and at 3, 6, and 9 months), thirty-eight patients were analysed, 19 with HSCT and 19 with MxTx with no differences in age, gender or diagnosis. The initial survey found significant differences only in pain perception, which was higher in the HSCT group (p = .08); at the first month, there was a greater tendency for feelings of depression or anxiety in the HSCT group (p = .016), with more limitations in social (p = .003) and daily (p = .044) activities. From 3 months post-HSCT, the results were very similar. The differences persisted only in the area of social activities. Four patients developed graft-versus-host disease with no significant difference in the scores obtained compared to other transplant patients at 3, 6, and 9 months (p = .26) of follow-up.     

Nigerian Clergy and healthcare professionals’ perceptions of health-seeking behaviours among Nigerian immigrants in the UK

The diversity in patient populations due to immigration in the UK has implications for adequate understanding of a patients’ culture by the clinician as well as patient–clinician cultural matching for enhanced service use and outcome. This qualitative study investigated how Nigerian clergy and health professionals perceived health-seeking behaviours among Nigerians in the UK, while considering the impact of their own beliefs and values as care providers. Six participants were interviewed (clergy, n?=?2; health professionals, n?=?4). Data were analysed using Interpretative Phenomenological Analysis. Results showed that the clergy and health professionals themselves use religious/cultural cure and formal healthcare methods, and believed Nigerian immigrants as predominantly using religious/cultural methods which can affect healthcare utilisation, although differences between the professionals were reported. The potentials for integrating other cure methods into the formal healthcare services were considered, while highlighting the challenges that may arise from such collaborative effort.     

Gender‐Related Psychological Characteristics and Situational Determinants of Psychophysiological Stress Reactivity1

This study examined the influence of gender‐related psychological characteristics and situational demands on physiological and affective responses to stressful tasks. While physiological and affective responses were monitored, 44 medical students (26 men, 18 women) performed an emotion‐oriented speech task and an action‐oriented speech in a counterbalanced design. Conventionally masculine instrumental and feminine expressive characteristics were measured using the Personal Attributes Questionnaire. Systolic blood pressure and respiratory reactions to the action‐oriented task were positively associated with expressivity. Expressivity was also associated with greater subjective tension during the action‐oriented task, and with perceptions of greater task difficulty. The results are consistent with the notion that physiological and affective stress reactions in men and women are determined in part by traditionally gender‐related psychological characteristics, with greater reactions when the situational demands are not congruent with preferred modes of behavior.     

Introducing the Expectations and Preference Scales for Couple Therapy (EPSCT): Development,Psychometric Evaluation,and Suggested Use in Practice and Research

While it is known that client factors account for the largest proportion of outcome variance across treatment modalities, little is known about how clients’ characteristics affect the process and effectiveness of couple therapy. To further knowledge in this area, we created a brief, practice‐friendly measure, the Expectation and Preference Scales for Couple Therapy (EPSCT). Three self‐report scales assess clients’ Outcome expectations (e.g., I expect our relationship to improve as a result of couple therapy) and role expectations for Self (e.g., I expect to listen to my partner's concerns) and Partner (e.g., I expect my partner to blame me). Three Cognitive‐Behavioral, Emotionally Focused, and Family Systems preference scales use a forced‐choice format to measure the comparative strength of respondents’ preferences for interventions broadly reflective of each approach. A large item pool was developed from relevant literature and clinical experience and refined based on face and content analyses with two panels of experienced couple therapists and researchers. Across four studies with 1,175 participants, the scales’ internal consistency reliabilities were similar and their construct validity was supported with confirmatory factor analyses and significant correlations with several established measures, including expectation measures developed for individual psychotherapy and measures of attitudes toward professional help seeking and valuing personal growth. Across all studies, participants had stronger role expectations for themselves than their partners, although gender effects differed by sample. We discuss how to use the 15‐item EPSCT in clinical practice and in future research as a predictor of couple therapy processes and outcomes.     

Choosing goals that express the true self: A novel mechanism of the effect of self-control on goal attainment

Why is trait self-control associated with successful goal progress? Existing research has attempted to answer this question by focusing on individual differences in the process of goal pursuit. Herein, we propose and test a novel mechanism suggesting that self-control facilitates goal attainment not only by affecting the process of goal pursuit but also the type of goals people select in the first place. Three studies showed that high (vs. low) self-control individuals are more likely to report successful goal attainment and this association was mediated by their tendency to select the goals that reflect their true/authentic self. These results were obtained using cross-sectional and longitudinal designs and were robust against controlling for previously established mechanisms of the effect of trait self-control on goal attainment (habit strength, experiences of goal-conflicting desires). Overall, there findings contribute to the literatures on self-regulation, authenticity and goal management.     

Broken Bodies,Broken Spirits: How Poor Health Contributes to a Cynical Worldview

Cynical hostility (or cynicism) is often considered as a major factor leading to bad health outcomes. The present research proposes that poor health might represent both a consequence and a source of cynicism. Using cross‐lagged path analyses, we documented bidirectional associations between health and cynicism in a nationally representative sample of Germans (Study 1) and a large sample of the American elderly (Study 2): cynical individuals were more likely to develop health problems, and poor health promoted the development of a cynical worldview over time. These results were obtained using different indicators of health status, including both self‐reported and interviewer‐administered physical measures. Longitudinal mediation analyses showed perceived constraints to mediate the effect of poor health on cynicism. This effect remained robust even when adding an alternative mediator—depressive symptoms. Additional analyses showed that any particular health limitation was prospectively related to cynicism to the degree to which this limitation was associated with an increased sense of constraints in individuals' life. © 2018 The Authors. European Journal of Personality published by John Wiley & Sons Ltd on behalf of European Association of Personality Psychology     

Speech rhythm alterations in Spanish-speaking individuals with Alzheimer’s disease

Rhythm is the speech property related to the temporal organization of sounds. Considerable evidence is now available for suggesting that dementia of Alzheimer’s type is associated with impairments in speech rhythm. The aim of this study is to assess the use of an automatic computerized system for measuring speech rhythm characteristics in an oral reading task performed by 45 patients with Alzheimer’s disease (AD) compared with those same characteristics among 82 healthy older adults without a diagnosis of dementia, and matched by age, sex and cultural background. Ranges of rhythmic-metric and clinical measurements were applied. The results show rhythmic differences between the groups, with higher variability of syllabic intervals in AD patients. Signal processing algorithms applied to oral reading recordings prove to be capable of differentiating between AD patients and older adults without dementia with an accuracy of 87% (specificity 81.7%, sensitivity 82.2%), based on the standard deviation of the duration of syllabic intervals. Experimental results show that the syllabic variability measurements extracted from the speech signal can be used to distinguish between older adults without a diagnosis of dementia and those with AD, and may be useful as a tool for the objective study and quantification of speech deficits in AD.     

Different Associations of Health Related Quality of Life with Pain,Psychological Distress and Coping Strategies in Patients with Irritable Bowel Syndrome and Inflammatory Bowel Disorder

The primary aim of this study was to measure psychological distress, pain severity, health related quality of life (QOL) and pain coping strategies in patients with irritable bowel syndrome (IBS) and ulcerative colitis (UC). A second aim was to determine the influence of somatic and psychological variables on health related QOL. Eighty-eight IBS and 66 UC patients completed the Irritable Bowel Syndrome Quality of Life Questionnaire (IBSQOL), Pain Severity Scale of West Haven Yale Multidimensional Pain Inventory (WHYMPY), Symptom Checklist-90-R (SCL-90-R) and Coping Strategies Questionnaire (CSQ). T-tests and GLM Analysis of Covariance were used for statistical analysis. IBS patients had significantly higher levels of psychological distress, pain severity and maladaptive pain coping strategies (catastrophization), and lower QOL than UC patients. Variance of QOL in IBS was explained for the most part by catastrophization (15%), then by psychological distress (8%), and for the less part by pain severity (5%). In UC, pain severity explained 21%, psychological distress 8%, and catastrophization 3% of the variance of QOL. These results suggest there are differences between IBS and UC patients in the role of physical and psychological factors in QOL and emphasize the importance of cognitive processes in IBS.     

Eliminating the memory blocking effect

Six experiments investigated the memory blocking effect (MBE) in which exposure to orthographically similar words (e.g., BALLOON) impairs one's ability to complete a similar fragment (e.g., BAL_ON_, solution is BALCONY). Experiments 1 and 2 demonstrated that blocking is not observed after a 72-hour delay; however, repetition priming was observed after the same delay. Experiments 3 and 4 showed that presenting unrelated semantic information during the fragment completion test eliminates blocking. Experiment 5 demonstrated that the MBE persists despite directed-forgetting instructions, and Experiments 5 and 6 demonstrated that activating both the solutions and blocking words for a particular fragment at study eliminates blocking. Collectively, the data demonstrate that reading orthographically similar primes automatically triggers retrieval of the blocking word and an executive control process works to manage this interference. A working framework that describes how an executive control mechanism could govern memory retrieval in the memory-blocking paradigm is presented to stimulate development of more advanced theoretical models that can explain blocking.