Implicit and explicit learning of event sequences: evidence for distinct coding of perceptual and motor representations

Event-related brain potentials (ERPs) of 21 subjects were recorded in a choice reaction time task with a repeating eight-element long stimulus sequence. The regular event sequence was sometimes interrupted by 'perceptual' or by 'motor deviants' which both replaced an expected stimulus but either preserved or violated the sequence of motor responses. Response times confirmed that all subjects had acquired some knowledge of the sequential dependencies. By means of a post-experimental free recall and recognition test, subjects were classified as having either explicit or implicit knowledge of the event sequence. The ERPs showed different effects for different types of stimuli and the two groups. In the group of explicit learners, a larger N200 component was evoked by both types of deviants and a larger P300 by motor deviants only. In the group of implicit learners these 'perceptual components' remained unaffected. In contrast, in both groups of subjects the lateralized readiness potential (LRP) which accompanied motor deviants revealed a partial activation of the to be expected but incorrect response, i.e. motor learning. These results suggest that explicit learners acquire knowledge about both, stimulus and response dependencies while implicit learners acquire knowledge about response dependencies only.     

Functional brain imaging as a looking-glass into the degraded brain: reviewing evidence from Alzheimer disease in relation to normal aging

Research on the real-time relationship between brain activity and mental performance is intense. However, relatively few studies have been devoted to patients with different diseases or lesions. Such studies may cast light on certain aspects of brain activity, such as plasticity. This review summarizes studies on Alzheimer's disease (AD) patients where the techniques to map brain activity in relation to mental performance have been utilized. Research findings suggest, that there is a spectrum of changes in AD patients that is distinct from that seen in healthy aging. These changes include: (i) loss of activated regions, (ii) reduced activation possibly due to brain degeneration typical of AD, (iii) the emergence of newly activated regions in order to compensate for minor brain deterioration (e.g., an enlargement of activated regions sometimes manifested as an increased bilaterality or a hemispheric shift of activation, and dedifferentiation), (iv) decreased level of activation, and (v) no change at all, which may occur in easy tasks or tasks that do not involve regions exposed to brain atrophy. In conclusion, the pattern of activation in AD depends on interactions between the clinical stage of patients, and the pattern of brain degeneration, as well as the task difficulty and specific networks necessary for solving the task.     

Individual development in a bio-cultural perspective

Biological and cultural inheritance deeply influence daily human behavior. However, individuals actively interact with bio-cultural information. Throughout their lives, they preferentially cultivate a limited subset of activities, values, and personal interests. This process, defined as psychological selection, is strictly related to the quality of subjective experience. Specifically, cross-cultural studies have highlighted the central role played by optimal experience or flow, the most positive and complex daily experience reported by the participants. It is characterized by high involvement, deep concentration, intrinsic motivation, and the perception of high challenges matched by adequate personal skills. The associated activities represent the basic units of psychological selection. Flow can therefore influence the selective transmission of bio-cultural information and the process of bio-cultural evolution.     

Large number discrimination in 6-month-old infants

Two experiments with the Stroop paradigm were conducted to investigate the role of phonological codes in access to the meaning of Chinese characters. Subjects named the ink color of viewed characters or color patches. Key items were color characters, their homophones with the same tone, homophones with different tones, and semantic associates. Apart from finding the usual Stroop interference effect, homophones produced significant interference in the incongruent condition, provided that they had the same tone as the color characters. The interference effect from homophones, however, was significantly smaller than that from color characters. Semantic associates generated an interference effect in the incongruent condition, an effect of the same magnitude as the effect from the same-tone homophones. Finally, in the congruent conditions, all the key items yielded facilitations compared to neutral controls, though the facilitation from color characters was larger than the facilitations from other types of characters. These findings suggest that phonological codes in Chinese are activated obligatorily and provide early sources of constraint in access to meaning.     

Family perception of interpersonal behavior as a predictor in eating disorders: a prospective, six-year followup study

This study assessed family perception patterns of interpersonal behavior in families with a daughter diagnosed with an eating disorder 6 years after treatment that used a prospective design. Family perception patterns of patients found to have a poor outcome at followup (n = 15) were compared with patients with a good outcome (n = 23), as well as a control group (n = 36). Using the system of multiple level observation of groups (SYMLOG), all 238 family members evaluated themselves and each other. The index patients with a poor outcome perceived themselves as friendlier and more positive than they were perceived by their families. In comparison to parents of daughters with a good outcome and the control group, parents of daughters in the poor outcome group perceived themselves to be less friendly than their partners perceived them to be. A rigid polarization of the perception of the index patient by family members and a discrepancy in this perception between the index patient and the rest of the family were found to be indicative of a poor prognosis. Implications for treatment based on family perception patterns of interpersonal behavior are discussed.     

The concreteness effect: evidence for dual coding and context availability

The term concreteness effect refers to the observation that concrete nouns are processed faster and more accurately than abstract nouns in a variety of cognitive tasks. Two models have been proposed to explain the neuronal basis of the concreteness effect. The dual-coding theory attributes the advantage to the access of a right hemisphere image based system in addition to a verbal system by concrete words. The context availability theory argues that concrete words activate a broader contextual verbal support, which results in faster processing, but do not access a distinct image based system. We used event-related fMRI to detect the brain regions that subserve to the concreteness effect. We found greater activation in the lower right and left parietal lobes, in the left inferior frontal lobe and in the precuneus during encoding of concrete compared to abstract nouns. This makes a single exclusive theory unlikely and rather suggests a combination of both models. Superior encoding of concrete words in the present study may result from (1) greater verbal context resources reflected by the activation of left parietal and frontal associative areas, and (2) the additional activation of a non-verbal, perhaps spatial imagery-based system, in the right parietal lobe.     

Interhemispheric inhibition, intrahemispheric activation, and lexical capacities of the right hemisphere: a tachistoscopic, divided visual-field study in normal subjects

This study proposes that the lexical-semantic capacities of the right hemisphere (RH) are underestimated in normal subjects and reexamines them in a "dynamic model" framework. As expected, overloading the left hemisphere by combining a lexical-decision task presented in divided visual field with a concurrent heavy verbal memory load, and activating the RH by combining the lexical-decision task with a concurrent visuo-imaged memory load, lead to enhanced left visual field-RH lexical performance. The RH appears to support a larger lexical-semantic network than suggested in the literature, including representations for long and nonimageable words, and the accessibility threshold for the representations stored therein is modulated by hemispheric activation-inhibition mechanisms.     

Mutual inhibition in collaborative recall: evidence for a retrieval-based account

In Experiment 1 participants gave 3 successive free recalls of items learned either individually or in pairwise collaboration. The first and third recalls were performed individually, the second alone or in collaboration. Collaborative recall led to an inhibitory effect after individual learning but not after collaborative learning, in which partners had similar retrieval strategies. Consistent with a retrieval locus for collaborative inhibition, non-recalled items reappeared in subsequent individual recall. Experiment 2 showed that collaborative inhibition was eliminated when a separate retrieval cue was given for each item. Experiments 2 and 3 also showed that when participants learned items in the same order, their retrieval strategies were more similar and they showed less collaborative inhibition. It is concluded that mutual interference in collaborative recall is due to the mutual disruption of individual retrieval strategies.     

Effects of directionality in deductive reasoning: I. The comprehension of single relational premises

Four experiments involving 123 university students tested directionality effects in the comprehension of spatial relations, quantified statements, and propositional connectives with a sentence-picture verification task. Presentation of the referents of terms in the statements was separated by 1 s, and presentation order was congruent or incongruent with the order of terms in the statement. Some relations showed faster verification times for congruent display order, others for incongruent display order, and still others showed no directionality effect. The authors proposed a 2-step process model for the construction of semantic representations of relational statements, in which a reference object is established first, and then the second object is attached in relation to it. This theory explains the various directionality effects as a general preference to process information about the reference object before information about the target object.