Spline smoothing with model-based penalties

Nonparametric regression techniques, which estimate functions directly from noisy data rather than relying on specific parametric models, now play a central role in statistical analysis. We can improve the efficiency and other aspects of a nonparametric curve estimate by using prior knowledge about general features of the curve in the smoothing process. Spline smoothing is extended in this paper to express this prior knowledge in the form of a linear differential operator that annihilates a specified parametric model for the data. Roughness in the fitted function is defined in terms of the integrated square of this operator applied to the fitted function. A fastO(n) algorithm is outlined for this smart smoothing process. Illustrations are provided of where this technique proves useful.     

Internalizing and externalizing characteristics of sexually and/or physically abused children

This study evaluates the behavioral consequences of childhood abuse (sexual, physical, or both), with particular focus on prevalence of posttraumatic stress disorder (PTSD). Three abuse type groups and nonabused controls were contrasted on behavioral rating scales and on structured psychiatric interview data. The participants (109 abused children and 16 normal control children) were recruited from Arkansas Children’s Hospital and local agencies for abused children. As expected, proportionately more females than males were sexually abused. Overall, males were rated as more disturbed than females. Type of abuse did not consistently influence behavioral ratings. Externalizing scores were significantly higher than internalizing scores in all abused groups. PTSD was diagnosed in 50% of the abused children, with a higher rate for boys who had been sexually abused as opposed to physically abused only (58% versus 13%). The most frequent comorbid condition with PTSD was Separation Anxiety. Sexually abused boys were hospitalized for psychiatric treatment at a higher rate than were other abused children.     

The organization of multidimensional selection on the basis of color and shape: An event-related brain potential study

In this paper, we examine whether color and shape, tied to a single object in space, (1) are identified and selected in series or in parallel, (2) are identified and selected in a dependent, self-terminating manner or in an independent and exhaustive manner, and (3) are conjoined by a feature integration process before or only after an initial stage of separate attribute analyses has finished. We measured response time and the selection negativity (SN) derived from event-related brain potentials when participants responded to a unique conjunction of color and shape in a go/no-go target detection task. The discriminability of the color and the shape of the conjunction was manipulated in three conditions. When color and shape were easy to discriminate, the SNs to color and shape started at the same time. When one attribute was less discriminable, the SN to that attribute started later, but not the SN to the complementary attribute. This suggests that color and shape are identified and selected in parallel. In all three discriminability conditions, the SNs to color and shape were initially independent but later interacted. This suggests that color and shape are initially selected independently and exhaustively, after which their conjunction is analyzed. The SN to local shape features started later than that to the conjunction of color and global shape features, which suggests that feature integration can start before the analyses of the separate attributes have finished.     

Perception of the Ponzo illusion by rhesus monkeys, chimpanzees, and humans: Similarity and difference in the three primate species

In Experiment 1, 3 rhesus monkeys and 1 chimpanzee were tested for their susceptibility to the Ponzo illusion. The subjects were first trained to report the length of the target bar presented at the center of the computer display by touching either of the two choice locations designated as “long” or “short.” When inverted-V context lines were superimposed on the target bar, the subjects tended to report “long” more often as the apex of these upward-converging lines approached the target bar. The perception of the Ponzo illusion was thus demonstrated. In Experiment 2, the same 3 rhesus monkeys and 2 new chimpanzees were tested using two types of context lines that provided different strengths of linear perspective. The subjects showed a bias similar to that found in Experiment 1, but there was no difference in the magnitude of the bias between the two types of context in either species. This failed to support the classic account for the Ponzo illusion, the perspective theory, raised by Gregory (1963). In Experiment 3, the magnitude of the illusion was compared between the inverted-V context and the context consisting of short vertical lines having the same gap as the former in the same 3 rhesus monkeys and 2 of the chimpanzees from the preceding experiments. While the chimpanzees showed the illusion for both types of stimuli, the monkeys showed no illusion for the latter. In Experiment 4, 6 humans were tested in a comparable procedure. As in the nonhuman primates, the illusion was unaffected by the strength of linear perspective. On the other hand, the humans showed considerably larger illusion for the context consisting of vertical lines than for contexts consisting of converging lines. Thus, there was a great species difference in the effect of the gap itself on the magnitude of the Ponzo illusion. Similarity found at first turned out to be no more than superficial. Possible sources of this species difference are discussed.     

Apocalyptic Argument and the Anticipation of Catastrophe: the Prediction of Risk and the Risks of Prediction

This essay proposes to extend the model of apocalyptic argument developedin my recent book Arguing the Apocalypse (OLeary, 1994) beyond the study ofreligious discourse, by applying this model to the debate over awell-publicized earthquake prediction that caused a widespread panic in theAmerican midwest in December, 1990. The first section of the essay willsummarize the essential elements of apocalyptic argument as I have earlierdefined them; the second section will apply the model to the case of the NewMadrid, Missouri, earthquake prediction, in order to demonstrate thatcertain patterns of reasoning characteristic of religious apocalyptic arepresent in the discourse over an anticipated local disaster. My ultimatepurpose is to show that predictions of global and local catastrophe mayserve as extreme cases that will illuminate the dynamics of predictiveargument in general. Thus my argument will seek to undercut Daniel Bellsdistinction between prophecy and prediction (Bell, 1973) by establishingthat these discourses share identifiable formal and substantivecharacteristics, and depend for their rhetorical effect on anxiety, hope,far, and excitement as modes of temporal anticipation.     

Imperialism,nationalism and missionaries: Lessons from Sudan for the twenty‐first century

Muslim‐Christian relations in modem Sudanese history involve the tensions created by the transition from imperial rule to independence and by the impact of contemporary processes of globalization. The conflicts between Christian missionaries and the newly‐independent government of Sudan in the early 1960s reflected the tensions between old mission‐station style Christian activities and attempts by a military régime to impose measures of ‘national’ unification. Opportunities for creating institutions for constructive interactions were missed or not even conceived. Lessons from the experiences of the early 1960s emphasize the importance of viewing Muslim‐Christian relations in the 1990s in the context of the actual current conditions rather than imposing out‐of‐date images on existing realities.     

The value of possessions in compulsive hoarding: Patterns of use and attachment

Hoarding behavior, patterns of use of possessions, and emotional attachment to possessions were examined among a sample of female undergraduates and a sample of community volunteers. Hoarding behavior was associated with a decreased frequency of use of possessions and excessive concern about maintaining control over possessions. Furthermore, high scores on the hoarding scale were associated with higher levels of perceived responsibility for: (1) being prepared; and (2) the well-being of the possession. Hoarding was also associated with greater emotional attachment to possessions and to the reliance on possessions for emotional comfort. The implications of these findings for the definition of hoarding are discussed.     

The effects of cocaine on behavior maintained by timeout from avoidance.

Rats were trained on concurrent schedules under which responses on one lever postponed shock (avoidance) and responses on the other lever produced brief (2-min) periods of signaled timeout from avoidance. For 6 rats, timeout from avoidance was programmed on a variable-interval 45-s schedule that generally resulted in rates that were lower than those on the avoidance lever. For another 6 rats, timeout was arranged on a variable-ratio 15 schedule that produced higher baseline rates. Cocaine (3 to 40 mg/kg) produced large, dose-dependent increases in behavior maintained by timeout in both groups of rats. Avoidance responding was also generally increased by cocaine, but the increases were of lesser magnitude. Increases in response rates were seen across a broad range of doses on behavior maintained by either interval or ratio schedules, an outcome that was unexpected on the basis of most studies of cocaine on food-maintained behavior. These results were similar to those of previous studies of the effects of amphetamine on behavior maintained by timeout from avoidance and suggest that stimulant drugs affect behavior maintained under a shock-postponement schedule differently than they affect behavior maintained by timeout from avoidance.     

Physicians' values and physician-value neutrality

For years articles have decried the lack of empathy in physicians' relationships with patients. In addition to being empathetic, physicians are called upon to assume the posture of value neutrality, i.e., not imposing one's values when dealing with patients. Empathy is clearly an expression of deeply held values; even the language used to define it is value-laden. Physicians are consistently called upon to exhibit traits which are expressions of their underlying values. However, if proponents of value-neutrality are to be taken literally one must not impose any of one's values on one's patients. But then one wonders how empathy could ever be expressed; further, it is hard to imagine what a truly value neutral physician would be like. It is time we recognize that any relationship between two persons requires the expression of values from both parties. These values help shape that relationship and define its further history. Physicians are not excluded from this process just because they consider themselves professionals. Divulging personal values to patients is both more honest and more in keeping with the concepts of justice, beneficence, non maleficence, and autonomy than to feign value-neutrality. A presentation of some type statement of values is timely and would give patients an idea of where a physician stands on a myriad of issues. Rather than being value-neutral, value non-neutrality seems a more right and reasonable posture for physicians to assume.