排序方式: 共有87条查询结果,搜索用时 6 毫秒
71.
Zinn CG Bevilaqua LR Rossato JI Medina JH Izquierdo I Cammarota M 《Neurobiology of learning and memory》2009,91(3):266-272
Evidence suggests that the NO/sGC/PKG pathway plays a key role in memory processing but the actual participation of this signaling cascade in the amygdala during memory consolidation remains unknown. Here, we show that when infused in the amygdala immediately after inhibitory avoidance training, but not later, the NO synthase inhibitor L-NNA hindered long-term memory retention without affecting locomotion, exploratory behavior, anxiety state or retrieval of the avoidance response. The amnesic effect of L-NNA was not state-dependent and was mimicked by the soluble guanylyl cyclase inhibitor LY83583 and the PKG inhibitor KT-5823. On the contrary, post-training intra-amygdala infusion of the NOS substrate L-Arg, the NO-releasing compound SNAP or the non-hydrolysable analog of cGMP 8Br-cGMP increased memory retention in a dose-dependent manner. Co-infusion of 8Br-cGMP reversed the amnesic effect of L-NNA and LY83583 but not that of KT-5823. Our data indicate that the NO-induced activation of PKG in the amygdala is a necessary step for consolidation of inhibitory avoidance memory. 相似文献
72.
The study of memories that pop into one's mind without any conscious attempt to retrieve them began only recently. While there are some studies on involuntary autobiographical memories (e.g., ) research on involuntary semantic memories or mind-popping is virtually non-existent. The latter is defined as an involuntary conscious occurrence of brief items of one's network of semantic knowledge. The recall of these items (e.g., a word, a name, a tune) is not accompanied by additional contextual information and/or involvement of self-a standard feature of involuntary autobiographical memories. The paper reports several diary and questionnaire studies which looked into the nature and frequency of occurrence of these memories. The data show that people do experience involuntary semantic memories which tend to occur without any apparent cues while being engaged in relatively automatic activities. Possible mechanisms of involuntary semantic memories are discussed (e.g., very long-term priming), and the results of the study provide information on the possible duration of the priming effects in everyday life. Related theoretical and methodological issues and future avenues of research in this neglected area are outlined. 相似文献
73.
Cammarota M Bevilaqua LR Medina JH Izquierdo I 《Learning & memory (Cold Spring Harbor, N.Y.)》2004,11(5):572-578
It has been suggested that retrieval during a nonreinforced test induces reconsolidation instead of extinction of the mnemonic trace. Reconsolidation would preserve the original memory from the labilization induced by its nonreinforced recall through a hitherto uncharacterized mechanism requiring protein synthesis. Given the importance that such a process would have in terms of maintaining, as part of the animal behavioral repertoire, a learned response that has been devalued by experience, we analyzed its existence for the memory associated with a one-trial, step-down inhibitory avoidance task (IA), a memory whose consolidation and extinction require protein synthesis in the CA1 region of the dorsal hippocampus (CA1) and involve the participation of the basolateral amygdala (BLA) and entorhinal cortex (ENT). Rats were trained in IA, and 24 h later they were submitted either to a pure reactivation session (retrieval without stepping down), which was unable by itself to initiate extinction of the avoidance response, or to a second training session. Fifteen minutes before or 3 h after either the reactivation or the retraining sessions, animals were infused with the protein synthesis inhibitor anisomycin (ANI) into CA1, BLA, or ENT. Contrary to the prediction of the reconsolidation hypothesis, none of these treatments affected subsequent memory retention. Because reconsolidation is regarded to be a direct consequence of retrieval, one would expect that, when given before a retention test or a pure reactivation session, enhancers of memory expression should permanently improve retention and, therefore, facilitate retrieval both in that and in subsequent sessions. Using two well-known retrieval enhancers, noradrenaline and adrenocorticotropin(1-24), we could not find any evidence suggestive of reconsolidation. Hence, our results indicate that there is no retrieval-induced, protein synthesis-dependent process that would cause reconsolidation of IA memory. 相似文献
74.
Kelly Jakubowski Amy M. Belfi Lia Kvavilashvili Abbigail Ely Mark Gill Gemma Herbert 《British journal of psychology (London, England : 1953)》2023,114(3):580-604
Previous research has found that music brings back more vivid and emotional autobiographical memories than various other retrieval cues. However, such studies have often been low in ecological validity and constrained by relatively limited cue selection and predominantly young adult samples. Here, we compared music to food as cues for autobiographical memories in everyday life in young and older adults. In two separate four-day periods, 39 younger (ages 18–34) and 39 older (ages 60–77) adults recorded their music- and food-evoked autobiographical memories in paper diaries. Across both age groups, music triggered more frequent autobiographical memories, a greater proportion of involuntary memories, and memories rated as more personally important in comparison to food cues. Age differences impacted music- and food-evoked memories similarly, with older adults consistently recalling older and less specific memories, which they rated as more positive, vivid, and rehearsed. However, young and older adults did not differ in the number or involuntary nature of their recorded memories. This work represents an important step in understanding the phenomenology of naturally occurring music-evoked autobiographical memories across adulthood and provides new insights into how and why music may be a more effective trigger for personally valued memories than certain other everyday cues. 相似文献
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76.
Tracy L. Durksen Man-Wai Chu Zaheen F. Ahmad Amanda I. Radil Lia M. Daniels 《Social Psychology of Education》2016,19(2):241-260
Self-determination theory (SDT) is one of the most well-known approaches to achievement motivation. However, the three basic psychological needs of SDT have not received equivalent attention in the literature: priority has been given to autonomy, followed by the need for competence, with research into relatedness lacking (Bachman and Stewart in Teach Psychol 38: 180–187, 2011. doi: 10.1177/0098628311411798). One new educational setting where relatedness may be particularly important is massive open online courses (MOOCs), which provide unprecedented opportunities for either relatedness or isolation. The purpose of the research was to use Bayesian networks (BN) to establish probabilistic relationships between learners’ basic psychological needs in the context of one MOOC. The majority (59 %) of participants (N = 1037; 50 % female and 50 % male) were under 45 (age range was 18–74 years). This sample represented approximately 88 regions and countries. Participants completed a revised Basic Student Needs Scale (Betoret and Artiga in Electron J Res Educ Psychol 9(2): 463–496, 2011). In order to reveal the best structural understanding of SDT within a MOOC learning environment, analysis of the data involved the development of a BN probabilistic model. The best fitting BN model included autonomy, competence, and relatedness—resulting in a probabilistic accuracy of 77.41 %. Analyses revealed participants with high autonomy had an 80.01 % probability of having a moderate level of competence. Relatedness was distinct from the autonomy and competence relationship. The strong inter-connections between autonomy and competence support existing research. The notion that relatedness may be a distinct need, at least in this context, was supported and warrants future research. 相似文献
77.
Filip Drozd Lia Mork Bettina Nielsen Sabine Raeder Cato Alexander Bjørkli 《The journal of positive psychology》2014,9(5):377-388
The internet seems promising for delivering interventions to enhance well-being in a normal population. The aim of this study was to test the effects of an internet-based positive psychology intervention targeting gratitude, pleasant activities, strengths, mastery, acts of kindness, optimism, flow, attributions, and mindfulness. One-hundred and twelve participants were randomized to the intervention and 94 to the control group, and data were collected at baseline, one, two, and six months after intervention onset. The balance of positive to negative affect increased over time among participants in the intervention group (unstandardized beta coefficient [B]?=?0.07, p?<?0.01), as compared to the controls (B?=?0.02, p?=?010). The intervention worked equally well regardless of participants’ gender, age, or education. However, optimism did not mediate the effect of the intervention on affect balance. In conclusion, the intervention had a small, but significant effect on affect balance among healthy adults. 相似文献
78.
Zeynep Biringen Della Derscheid Nicole Vliegen Lia Closson M. Ann Easterbrooks 《Developmental Review》2014
Emotional availability (EA), as a construct, refers to the capacity of a dyad to share an emotionally healthy relationship. The Emotional Availability (EA) Scales assess this construct using a multi-dimensional framework, with scales measuring the affect and behavior of both the child and adult partner (caregiver). The four caregiver components are sensitivity, structuring, non-intrusiveness, and non-hostility. The two child components are the child’s responsiveness to the caregiver and the child’s involvement of the caregiver. We first describe this relationship construct, look at psychometric properties in basic and prevention/intervention efforts, then review the extant empirical literature in order to examine the scope of studies assessing EA by using the EA Scales. We also explore its use in clinical practice. Throughout, we critically evaluate the knowledge base in this area as well as identify areas for further growth. 相似文献
79.
Wendy S. Francis Randolph S. Taylor Marisela Gutiérrez Mary K. Liaño Diana G. Manzanera Renee M. Penalver 《Memory (Hove, England)》2018,26(10):1364-1378
Two experiments investigated how well bilinguals utilise long-standing semantic associations to encode and retrieve semantic clusters in verbal episodic memory. In Experiment 1, Spanish-English bilinguals (N?=?128) studied and recalled word and picture sets. Word recall was equivalent in L1 and L2, picture recall was better in L1 than in L2, and the picture superiority effect was stronger in L1 than in L2. Semantic clustering in word and picture recall was equivalent in L1 and L2. In Experiment 2, Spanish-English bilinguals (N?=?128) and English-speaking monolinguals (N?=?128) studied and recalled word sequences that contained semantically related pairs. Data were analyzed using a multinomial processing tree approach, the pair-clustering model. Cluster formation was more likely for semantically organised than for randomly ordered word sequences. Probabilities of cluster formation, cluster retrieval, and retrieval of unclustered items did not differ across languages or language groups. Language proficiency has little if any impact on the utilisation of long-standing semantic associations, which are language-general. 相似文献
80.
Parker Patti C. Perry Raymond P. Chipperfield Judith G. Hamm Jeremy M. Daniels Lia M. Dryden Robert P. 《Social Psychology of Education》2022,25(5):1031-1049
Social Psychology of Education - Research suggests that when dealing with personal setbacks, secondary control (SC) adjustment and acceptance beliefs can foster psychological wellbeing. However,... 相似文献