Genetic Cancer Risk Assessment and Counseling: Recommendations of the National Society of Genetic Counselors

These cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of identifying at-risk individuals through cancer risk assessment with or without genetic testing. They were developed by members of the Practice Issues Subcommittee of the National Society of Genetic Counselors Cancer Genetic Counseling Special Interest Group. The information contained in this document is derived from extensive review of the current literature on cancer genetic risk assessment and counseling as well as the personal expertise of genetic counselors specializing in cancer genetics. The recommendations are intended to provide information about the process of genetic counseling and risk assessment for hereditary cancer disorders rather than specific information about individual syndromes. Key components include the intake (medical and family histories), psychosocial assessment (assessment of risk perception), cancer risk assessment (determination and communication of risk), molecular testing for hereditary cancer syndromes (regulations, informed consent, and counseling process), and follow-up considerations. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. These recommendations do not displace a health care provider's professional judgment based on the clinical circumstances of a client.     

A psychological model that integrates ethics in engineering education

Ethics has become an increasingly important issue within engineering as the profession has become progressively more complex. The need to integrate ethics into an engineering curriculum is well documented, as education does not often sufficiently prepare engineers for the ethical conflicts they experience. Recent research indicates that there is great diversity in the way institutions approach the problem of teaching ethics to undergraduate engineering students; some schools require students to take general ethics courses from philosophical or religious perspectives, while others integrate ethics in existing engineering courses. The purpose of this paper is to propose a method to implement the integration of ethics in engineering education that is pedagogically based on Kohlberg’s stage theory of moral development.     

Haptic processing of the location of a known property: does knowing what you've touched tell you where it is?

The relationship between knowing where a haptic property is located and knowing what it is was investigated using a haptic-search paradigm. Across trials, from one to six stimuli were presented simultaneously to varying combinations of the middle three fingertips of both hands. Participants reported the presence/absence of a target or its location for four perceptual dimensions: rough/smooth, edge/no edge, relative position (right/left), and relative orientation (right/left). Reaction time data were plotted as a function of set size. The slope data indicated no difference in processing load for location as compared to identity processing. However, the intercept data did reveal a cost associated with processing location information. Location information was not obtained for "free" when identity was processed. The data also supported a critical distinction between material and edge dimensions versus geometric dimensions, as the size of the cost associated with processing location was larger for spatial than for intensive stimuli.     

Semantic priming of different affective categories

The authors investigated affective semantic priming using a lexical decision task with 4 affective categories of related word pairs: neutral, happy, fearful, and sad. Results demonstrated a striking and reliable effect of affective category on semantic priming. Neutral and happy prime-targets yielded significant semantic priming. Fearful pairs showed no or modest priming facilitation, and sad primes slowed reactions to sad targets. A further experiment established that affective primes do not have generalized facilitatory-inhibitory effects. The results are interpreted as showing that the associative mechanisms that support semantic priming for neutral words are also shared by happy valence words but not for negative valence words. This may reflect increased vigilance necessary in adverse contexts or suggest that the associative mechanisms that bind negative valence words are distinct.     

Cognitive-behavioural interventions in a patient with an anxiety disorder related to diabetes

This study extends the data on the efficacy of cognitive interventions for patients with chronic medical problems and describes the case of a 37-year-old woman with an anxiety disorder related to diabetes. The effects on panic frequency, use of safety behaviour and related beliefs were investigated after the introduction of two main cognitive-behavioral interventions. The results are consistent with predictions from the cognitive model of panic. This case demonstrates the usefulness of directly challenging the 'meaning' of the feared situation in order to produce clinically significant improvements in the management of physical disease.     

John Bowlby and Margaret s. Mahler: their lives and theories

Traumatic aspects of the lives of John Bowlby and Margaret Mahler can be seen to inform their intellectual careers, a perspective that suggests that attachment theory and separation-individuation theory are far more consonant with one another than otherwise. Articulating the domains of convergence between the two theories reveals the essential complementarity of the special strengths of each. Both theories were attempts to understand the role of experience in the development of mental representations. Mahler paid close clinical attention to inner mental states and their evolution, while Bowlby searched for behavioral correlates that could lend themselves to empirical observation and inferences about internal representations.     

A structural analysis of working memory and related cognitive skills in young children

The aim of this study was to investigate the functional organisation of working memory and related cognitive abilities in young children. A sample of 633 children aged between 4 and 6 years were tested on measures of verbal short-term memory, complex memory span, sentence repetition, phonological awareness, and nonverbal ability. The measurement model that provided the best fit of the data incorporates constructs that correspond to the central executive, phonological loop, and episodic buffer subcomponents of working memory, plus distinct but associated constructs associated with phonological awareness and nonverbal ability.     

College students and HIV/AIDS: more insights on knowledge, testing, and sexual practices

In this study, the authors confirm and expand previous findings (M. Anastasi, R. G. Sawyer, & P. J. Pinciaro, 1999; J. E. Lewis & R. M. Malow, 1997) concerning college students' knowledge and perceptions about HIV/AIDS. Although students are knowledgeable about HIV/AIDS, they have little personal concern about becoming infected and do not take appropriate safe sex precautions. Findings of the present study show that gender, ethnic background, and knowing someone infected by HIV/AIDS influence students' level of concern about infection. In addition, older students and those who know someone infected by HIV/AIDS are more likely to have been tested. Results are compared with national surveys of other age groups, and the authors suggest specific intervention strategies for college students.     

Haptic identification of common objects: effects of constraining the manual exploration process

In this article, we address the effects on haptic recognition of common objects when manual exploration is constrained by using two kinds of rigid links--sheaths (Experiment 1A) and probes (Experiments 1B and 2). The collective effects of five different constraints are considered, including three from previous research (i.e., reducing the number of end effectors, wearing a compliant finger cover, and splinting the fingers; Klatzky, Loomis, Lederman, Wake, & Fujita, 1993) and from two current constraints (i.e., wearing a rigid finger sheath and using a rigid probe). The resulting impairments are interpreted in terms of the loss of somatosensory information from cutaneous and/or kinesthetic inputs. In addition, we relate the results to the design of haptic interfaces for teleoperation and virtual environments, which share some of the same reduction of sensory cues that we have produced experimentally.     

Brief maternal interaction increases number, amplitude, and bout size of isolation-induced ultrasonic vocalizations in infant rats (Rattus norvegicus)

The number, amplitude, duration, and bout structure of isolation-induced ultrasonic vocalization (USV) of infant rats (Rattus norvegicus) were measured on postnatal Day 10. Measurements were made before and after a brief, 1-min, active interaction with their mother or before and after a "pick-up" control procedure. Consistent with prior studies, the number of USVs emitted was significantly increased in the period following the maternal reunion but not after the control procedure. The average amplitude of USVs was also greater following maternal reunion. Finally, analyses characterizing the bout structure of USV production indicated that the average bout size (i.e. number of USVs/bout) was increased severalfold following the reunion with the mother, accounting for the greater rate of USV production during the second isolation period.