The Dopamine Receptor D4 Gene (<Emphasis Type="Italic">DRD4</Emphasis>) Moderates Family Environmental Effects on ADHD

Attention-Deficit/Hyperactivity Disorder (ADHD) is a prime candidate for exploration of gene-by-environment interaction (i.e., G x E), particularly in relation to dopamine system genes, due to strong evidence that dopamine systems are dysregulated in the disorder. Using a G x E design, we examined whether the DRD4 promoter 120-bp tandem repeat polymorphism, previously associated with ADHD, moderated the effects of inconsistent parenting and marital conflict on ADHD or Oppositional-Defiant Disorder (ODD). Participants were 548 children with ADHD and non-ADHD comparison children and their parents. Homozygosity for the DRD4 promoter 120-bp tandem repeat insertion allele increased vulnerability for ADHD and ODD only in the presence of inconsistent parenting and appeared to increase susceptibility to the influence of increased child self-blame for marital conflict on ADHD inattention. DRD4 genotypes may interact with these proximal family environmental risk factors by increasing the individual’s responsivity to environmental contingencies.     

The effect of local kinematic changes on anticipation judgments

Skilled tennis players rely on a more global than local perceptual strategy when anticipating an opponent’s shot direction in tennis (Williams, Huys, Cañal-Bruland, & Hagemann, 2009). Global perceptual strategy refers to the pick-up of dynamic information across different body areas rather than from a single source such as the arm or racket. We extend previous work by examining the spatiotemporal characteristics of visual information pick-up when anticipating shot direction in tennis. We perturbed information from various body locations by interchanging the dynamics of selected areas with those from strokes played to the opposite side of the court. In addition, we presented each manipulation under four different temporal occlusion conditions (from 240 ms prior to racket-ball contact) to examine the time course of information extraction. Skilled tennis players outperformed less skilled counterparts in predicting shot direction, even at early phases of the opponent’s motion. Moreover, skilled players showed significant decrements in performance when the arms and racket were perturbed, highlighting the relevance of distal information when anticipating opponents’ intentions.     

African American Women’s Limited Knowledge and Experiences with Genetic Counseling for Hereditary Breast Cancer

Genetic counseling and testing for hereditary breast cancer have the potential benefit of early detection and early interventions in African American women. However, African American women have low use of these services compared to White women. We conducted two focus groups with African American women diagnosed with breast cancer (affected group, n?=?13) and women with at least one first-degree relative with breast/ovarian cancer (unaffected group, n?=?8). A content analysis approach was employed to analyze interview data. Breast cancer survivors had more knowledge about genetic counseling and testing than participants who were unaffected with cancer. However, knowledge about genetic counseling was limited in both groups. Barriers to pursuing genetic counseling and testing included poor understanding of the genetic counseling and testing process, fear of carrying the mutation, concerns about discrimination, and cost. Motivators to participate in genetic counseling and testing included desire to help family members, insurance coverage, and potential of benefiting the larger African American community. Education efforts are needed to increase genetic counseling and testing awareness in the African American community.     

An Assessment of Time Involved in Pre-test Case Review and Counseling for a Whole Genome Sequencing Clinical Research Program

Whole genome sequencing (WGS) is being used for evaluation of individuals with undiagnosed disease of suspected genetic origin. Implementing WGS into clinical practice will place an increased burden upon care teams with regard to pre-test patient education and counseling about results. To quantitate the time needed for appropriate pre-test evaluation of participants in WGS testing, we documented the time spent by our clinical research group on various activities related to program preparation, participant screening, and consent prior to WGS. Participants were children or young adults with autism, intellectual or developmental disability, and/or congenital anomalies, who have remained undiagnosed despite previous evaluation, and their biologic parents. Results showed that significant time was spent in securing allocation of clinical research space to counsel participants and families, and in acquisition and review of participant’s medical records. Pre-enrollment chart review identified two individuals with existing diagnoses resulting in savings of $30,000 for the genome sequencing alone, as well as saving hours of personnel time for genome interpretation and communication of WGS results. New WGS programs should plan for costs associated with additional pre-test administrative planning and patient evaluation time that will be required to provide high quality care.     

ABA and ABC Renewal during Ongoing Omission Training

The Psychological Record - Renewal is one form of behavioral relapse in which a previously reduced response reemerges following a contextual change. Renewal is prevalent during clinical...     

It’s a Matter of Organizational Pride: How Perceptions of Organizational Virtuousness and Competence Affect Employee Behaviors

Journal of Business and Psychology - Companies often discuss the importance of organizational pride and what they believe leads to it, yet research on this topic in the organizational sciences has...     

The Role of Parents’ School Climate Perceptions on Attainment Expectations for Black Middle Schoolers

Journal of Child and Family Studies - Parents’ beliefs about their children’s schools are important influences on their parenting and on their children’s outcomes. Because of...     

Validation of the Karitane Parenting Confidence Scale in Measuring Parental Self-Efficacy of Australian Fathers

Journal of Child and Family Studies - Parental Self Efficacy (PSE) is a key predictor of positive parenting practices and child outcomes. The Karitane Parenting Confidence Scale (KPCS) is a global...     

African American Children’s Racial Discrimination Experiences and Mental Health

Journal of Child and Family Studies - The current study examined how African American children’s experiences of perceived personal racial discrimination and perceived vicarious racial...