The functional anatomy of inspection time: a pilot fMRI study

Seven healthy subjects underwent functional magnetic resonance imaging (fMRI) of the brain while performing an inspection time task. Employing a block-type design, the task had three difficulty levels: a control condition, an easy (200 ms stimulus duration), and a more difficult (40 ms) discrimination. Based on group results, there were widespread significant areas of difference in brain activation and deactivation when pairwise comparisons were conducted among the three task conditions. When the difficult condition was compared with the easy condition, there was relative activation in areas of the following brain regions: cingulate gyrus and some frontal and parietal lobe areas. Areas within the following regions showed relative deactivation (greater blood oxygenation level-dependent, BOLD, signal in the easy condition): frontal, temporal, and parietal lobe. There were overlaps between these areas and those found to be active while performing higher cognitive tasks in other functional brain imaging studies. These pilot data encourage future studies of the functional anatomy of inspection time and its relevance to psychometric intelligence.     

Ontogenetic changes in the neural mechanisms of eyeblink conditioning

The rodent eyeblink conditioning paradigm is an ideal model system for examining the relationship between neural maturation and the ontogeny of associative learning. Elucidation of the neural mechanisms underlying the ontogeny of learning is tractable using eyeblink conditioning because the necessary neural circuitry (cerebellum and interconnected brainstem nuclei) underlying the acquisition and retention of the conditioned response (CR) has been identified in adult organisms. Moreover, the cerebellum exhibits substantial postnatal anatomical and physiological maturation in rats. The eyeblink CR emerges developmentally between postnatal day (PND) 17 and 24 in rats. A series of experiments found that the ontogenetic emergence of eyeblink conditioning is related to the development of associative learning and not related to changes in performance. More recent studies have examined the relationship between the development of eyeblink conditioning and the physiological maturation of the cerebellum, a brain structure that is necessary for eyeblink conditioning in adult organisms. Disrupting cerebellar development with lesions or antimitotic treatments impairs the ontogeny of eyeblink conditioning. Studies of the development of physiological processes within the cerebellum have revealed striking ontogenetic changes in stimulus-elicited and learning-related neuronal activity. Neurons in the interpositus nucleus and Purkinje cells in the cortex exhibit developmental increases in neuronal discharges following the unconditioned stimulus (US) and in neuronal discharges that model the amplitude and time-course of the eyeblink CR. The developmental changes in CR-related neuronal activity in the cerebellum suggest that the ontogeny of eyeblink conditioning depends on the development of mechanisms that estavlish cerebellar plasticity. Learning and the induction of neural plasticity depend on the magnitude of the US input to the cerebellum. The role of developmental changes in the efficacy of the US pathway has been investigated by monitoring neuronal activity in the inferior olive and with stimulation techniques. The results of these experiments indicate that the development of the conditioned eyeblink response may depend on dynamic interactions between multiple developmental processes within the eyeblink neural circuitry.     

Reflectivity, Reflection, and Counter-Education

This article sets forward a new concept of reflection, to be contrasted with more usual reading of the concept for which we use the term `reflectivity'. The contrast is related to a distinction between normalizing education and counter-education. We claim that within the framework of normalizing education there is no room for reflection, but only for reflectivity. In contrast to reflectivity, reflection manifests a struggle of the subject against the effects of power which govern the constitution of her conceptual apparatus, her knowledge, her consciousness and her limitations and possibilities for successful functioning. Reflectivity re-presents the hegemonic realm of self-evidence and the productive violence of social and cultural order. Reflection, by contrast, aims to challenge the supposedly self-evident and the present order of things. Reflection aims at transcendence and represents a moral commitment in respect of the otherness of the Other, which power relations in every realm of self-evidence oblige us to neglect, to destroy or consume. Transcendence is a concrete utopia, and so is the subject in her nonrepressive communication with the Other: they are part and parcel of our present possibilities, sometimes in microscopic arenas, struggled for, and from time to time even realized.     

Teachers' judgments of preschoolers' creativity

This study investigated the relationship of objective measures of preschoolers' ideational fluency and intelligence to teachers' ratings of creativity and desirability. The sample of 60 4-yr.-olds and 39 teachers were from six classrooms. Teachers' ratings of creativity were related to measures of intelligence (r = .46, p less than .001) but not to ideational fluency (r = .10). These findings are discussed in relation to possible halo effects and the ability to discriminate adequately cognitive abilities among preschool children.     

Outcome of hospitalization for defendants found incompetent to stand trial

This study assessed the outcome of hospitalization for incompetent criminal defendants admitted to the forensic unit of a state hospital for treatment during a 4-year period. Findings suggested that the overwhelming majority of the defendants were restored to competency. The defendants also showed significant improvement in overall severity of psychopathology during hospitalization. Further, the duration of hospitalization for these defendants was relatively short. Although these results are promising with regard to treatment of incompetent defendants, predicting the outcome of hospitalization for these defendants was problematic. Prediction of competency restoration was precluded because persistent incompetence was so infrequent. Moreover, multiple regression analyses suggested limited predictive ability with regard to defendants' discharge level of functioning or length of hospitalization. These findings are consistent with the view that examiners should exercise caution in making recommendations to the courts concerning treatability of incompetent defendants.     

Neuropsychological Aspects of Multiple Sclerosis

Since S. Rao's [Neuropsychology of Multiple Sclerosis: A Critical Review, A Journal of Clinical and Experimental Neuropsychology, Vol. 85, pp. 503–542] (1986) seminal review, considerable research has been undertaken on the neuropsychological consequences of multiple sclerosis. This review incorporates the research literature of the last decade in presenting an overview of the current state of our knowledge concerning the etiology, course, symptoms, assessment, consequences, and treatment of multiple sclerosis (MS). The concept of subcortical dementia is revisited in light of the most recent literature documenting the neuropsychological deficits in patients with MS. The view that cognitively heterogeneous patient groups may disguise more specific patterns of focal neuropsychological impairment is considered. A critical review of the recent literature is also presented, detailing the degree to which recent research has addressed the areas of research need identified by Rao in 1986. Given recent advances in our knowledge, the need for more attention to be directed toward the evaluation of rehabilitation and psychological intervention is highlighted.     

Poststroke depression: Prevalence,course, and associated factors

Despite the considerable amount of research that has been undertaken on poststroke depression, a review of the literature demonstrates that there are many inconclusive findings in the area. In particular, the causes and course of the disorder remain to be firmly established. While studies of prevalence differ with respect to the nature and timing of their assessment procedures, most conclude that poststroke depression has a negative impact on the rehabilitation of the stroke patient. Very little research is available on the relationship between poststroke depression and care-giver burden. However, recent studies have adopted more rigorous methodological procedures, allowing some insights into the complex mixture of factors which determine the occurrence of poststroke depression.