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471.
Wassum KM Ostlund SB Balleine BW Maidment NT 《Learning & memory (Cold Spring Harbor, N.Y.)》2011,18(7):475-483
Here we attempted to clarify the role of dopamine signaling in reward seeking. In Experiment 1, we assessed the effects of the dopamine D(1)/D(2) receptor antagonist flupenthixol (0.5 mg/kg i.p.) on Pavlovian incentive motivation and found that flupenthixol blocked the ability of a conditioned stimulus to enhance both goal approach and instrumental performance (Pavlovian-to-instrumental transfer). In Experiment 2 we assessed the effects of flupenthixol on reward palatability during post-training noncontingent re-exposure to the sucrose reward in either a control 3-h or novel 23-h food-deprived state. Flupenthixol, although effective in blocking the Pavlovian goal approach, was without effect on palatability or the increase in reward palatability induced by the upshift in motivational state. This noncontingent re-exposure provided an opportunity for instrumental incentive learning, the process by which rats encode the value of a reward for use in updating reward-seeking actions. Flupenthixol administered prior to the instrumental incentive learning opportunity did not affect the increase in subsequent off-drug reward-seeking actions induced by that experience. These data suggest that although dopamine signaling is necessary for Pavlovian incentive motivation, it is not necessary for changes in reward experience, or for the instrumental incentive learning process that translates this experience into the incentive value used to drive reward-seeking actions, and provide further evidence that Pavlovian and instrumental incentive learning processes are dissociable. 相似文献
472.
The functions of the medial longitudinal arch have been the focus of much research in recent years. Several studies have shown kinematic differences between high- and low-arched runners. No literature currently compares the inter-segmental foot motion of high- and low-arched recreational athletes. The purpose of this study was to examine inter-segmental foot motion in the frontal plane during dynamic loading activities in high- and low-arched female athletes. Inter-segmental foot motions were examined in 10 high- and 10 low-arched female recreational athletes. Subjects performed five barefooted trials in each of the following randomized movements: walking, running, downward stepping and landing. Three-dimensional kinematic data were recorded. High-arched athletes had smaller peak ankle eversion angles in walking, running and downward stepping than low-arched athletes. At the rear-midfoot joint high-arched athletes reached peak eversion later in walking and downward stepping than the low-arched athletes. The high-arched athletes had smaller peak mid-forefoot eversion angles in walking, running and downward stepping than the low-arched athletes. The current findings show that differences in foot kinematics between the high- and low-arched athletes were in position and not range of motion within the foot. 相似文献
473.
手术室是高风险的医疗场所,手术室患者安全已成为医院患者安全管理的重中之重,尤其在广大患者对健康要求日益增加、维权意识逐步提高的今天,手术室患者安全再次被提到新的高度.本文从我国手术室患者安全的现状出发,深入剖析了影响手术室患者安全的相关因素,找出了适合手术室患者安全管理的应对策略,最后对影响手术室患者安全的深层次问题进行了必要的思考. 相似文献
474.
475.
文章采用教师组织公民行为与教师教学效能感问卷,对广州市的205名初中教师进行了研究,以探讨学校等级、性别、职称、学历、教龄等背景变量对初中教师组织公民行为、教学效能感的影响,以及教师组织公民行为与教师教学效能感之间的关系。结果发现:教师组织公民行为、教学效能感在学校等级和职称上存在着显著性差异;教师组织公民行为与教师教学效能感之间存在着显著性相关,教师组织公民行为中的认同组织和良心行为因子是教师教学效能感的有效预测变量。 相似文献
476.
Ten stuttering and ten nonstuttering children, ages 4–8 yr, served as subjects for a motor reaction task to simple and complex linguistic stimuli. The subjects reacted by pressing one of four panels on a touch-sensitive board that depicted the appropriate semantic relationship in response to 30 simple and complex linguistic stimuli. There was a significant increase in the reaction time of both groups with increasing linguistic complexity. No significant differences were found in the reaction time between the two groups, nor in the interaction between group and complexity. Implications regarding linguistic processing are discussed, and an “overload” hypothesis of stuttering is dispelled. It is concluded that stutterers and nonstutterers in this study did not differ in their reaction time nor in their processing time of linguistic material. 相似文献
477.
Children's ability to transfer what they learn in one situation to analogous problems was examined in a series of four studies. Subjects ranged in age from 3 to 10 years. The problems involved novel uses of familiar tools or simple biological themes such as mimicry as a method of defence. The data suggest that the apparent transfer reluctance shown by children in previous studies is the result of what they have been required to learn and the conditions under which they have been required to learn it. In the present studies, children as young as 3 years transferred readily if the problem domain was one they understood and engaged in, and if the traditional laboratory paradigm was modified so as to promote transfer rather than just to test for its spontaneous occurrence. 相似文献
478.
479.
Jerry Slotkin Rex Forehand Robert Fauber Amanda McCombs Nicholas Long 《Journal of abnormal child psychology》1988,16(2):207-217
The purpose of this study was to examine the relationship of both young adolescents' scores on the Children's Depression Inventory (CDI) and their mothers' ratings of the adolescents' depression (parent-completed CDI) to indices of their social and cognitive functioning obtained from a source outside the home. Subjects consisted of a nonclinic sample of 85 young adolescents (11–15 years of age), their mothers, and their social studies teachers. Recent school grades and teacher-completed measures served as the indices of adolescent social and cognitive competence. The results indicated that both adolescents' and mothers' CDI scores were significantly and negatively correlated with measures of adolescent cognitive and social functioning. Multiple regression analyses, utilizing adolescent- and parent-completed CDI scores as predictors, indicated that both predictor variables entered into the equations for cognitive functioning while only the mother-completed CDI entered into those for social functioning. When maternal depression was also entered into the multiple regressions, the findings regarding mother- and adolescent-completed CDI scores were not altered. The relationship of these findings to other somewhat disparate findings concerning the utility of mother and child reports of child depression is discussed.This research was supported, in part, by the William T. Grant Foundation and the University of Georgia's Institute for Behavioral Research. 相似文献