Selective attention and inhibitory deficits in ADHD: Does subtype or comorbidity modulate negative priming effects?

Selective attention has durable consequences for behavior and neural activation. Negative priming (NP) effects are assumed to reflect a critical inhibitory component of selective attention. The performance of adolescents with Attention Deficit/Hyperactivity Disorder (ADHD) was assessed across two conceptually based NP tasks within a selective attention procedure. Comorbidity (non-comorbid ADHD vs. comorbid ADHD) and subtype (ADHD combined vs. ADHD inattentive) were considered key issues. Results found NP effects to differ as a function of comorbidity but not subtype. Findings are discussed in light of functional neuroimaging evidence for neuronal enhancement for unattended stimuli relative to attended stimuli that strongly complements an inhibitory-based explanation for NP. Implications for the ‘AD’ in ADHD and contemporary process models of the disorder are considered.     

Aggravation of DSS-induced colitis after chronic subordinate colony (CSC) housing is partially mediated by adrenal mechanisms

Chronic subordinate colony housing (CSC) is a relevant chronic psycho-social stressor for male mice. Here, we investigated effects of CSC on the severity of dextran sulphate sodium (DSS)-induced colitis and the involvement of adrenal mechanisms. After 19 days of CSC, male C57BL/6 mice were treated with 1% DSS (8 days). After 8 days, inflammatory shortening of the colon and the histological inflammation score were increased in CSC mice. Additionally, the increased secretion of pro-inflammatory cytokines by mesenteric lymph node cells found on day 2 and 4 of DSS treatment was down-regulated in CSC mice on day 8 of DSS treatment, paralleled by an increase in plasma corticosterone. In contrast, in unstressed controls, elevation of cytokine secretion was delayed and only found on day 8 of DSS treatment, associated with a prompt rise in plasma corticosterone. To reveal adrenal mechanisms in CSC-induced effects on colitis, mice were adrenalectomized, exposed to CSC and treated with DSS (8 days). In adrenalectomized CSC mice, the severity of DSS-induced colitis was reduced, as body weight loss, shortening of colon, histological damage score, and cytokine secretion from mesenteric lymph node cells were diminished compared with sham-operated CSC mice. In conclusion, exposure to chronic psycho-social stress increases the severity of acute DSS colitis, an effect which is, at least partly, mediated by adrenal mechanisms.     

Detection strategies for malingering with the Miller Forensic Assessment of Symptoms Test: a confirmatory factor analysis of its underlying dimensions

Two of the most widely used measures for the assessment of malingering in forensic populations are the Miller Forensic Assessment of Symptoms Test (M-FAST) and the Structured Interview of Reported Symptoms (SIRS). The underlying dimensions of the SIRS have been well established in the literature, but the structure of the M-FAST remains relatively untested. Understanding of its dimensions is critical for construct validity and guiding its proper use. Confirmatory factor analysis was used to provide evidence of a single parsimonious malingering factor to account for the covariation of the M-FAST items in a sample of 244 forensic patients. In addition, the model was cross-validated with an independent sample of 210 forensic patients. Finally, the M-FAST factor was modeled in conjunction with two factors of the SIRS. Results provide further validation of the underlying detection strategy found in the M-FAST.     

Modular Treatment for Children and Adolescents With Problematic School Absenteeism: Development and Description of a Program in Germany

Problematic school absenteeism is defined as absence from school occurring with a clinical-level mental disorder. It represents a higher-order term for school refusal, school truancy, and the combination thereof and is associated with an increased risk for school dropout, prolonged mental disorders, and unemployment. This article describes the manualized modular treatment of problematic school absenteeism (MT) by a multiprofessional team. The manual was developed to target a broad spectrum of mental disorders characterized by internalizing but also externalizing behavior. The therapeutic focus is on the reintegration into school and on the cognitive behavioral treatment of the mental disorder. The MT is based on a multilevel model of problematic school absenteeism. The treatment is informed by an extensive case-conceptualization and addresses motivational aspects by offering a low-threshold therapeutic design and motivational interviewing. Core interventions are represented in four modules: cognitive behavioral therapy, family counseling, school counseling, and a psychoeducational physical exercise program. A case vignette provides an illustration of the treatment and the specific graduated approach for school reintegration. The current modular approach is discussed in relation to other cognitive-behavioral manuals targeting a broad spectrum of mental disorders or school refusal.     

The effects of priming subjective control on reports of fear

Motivation and Emotion - According to appraisal theories, fear-related emotions are essentially influenced by appraisals of personal control. Most appraisal theories propose that control appraisals...     

Whistle-Blowing from the Perspective of General Strain Theory

Authorities in many countries rely on whistle-blowing systems to boost control of organizational deviance. It can hardly be answered whether this practice is legitimate and efficient without knowing the patterns of whistle-blower behavior. So far, little is known about the development process as an interaction of specific individual, organizational, and situational conditions that spawns especially external reports. This article reconstructs such typical progressions based on interviews with whistle-blowers in Germany and from the perspective of the General Strain Theory. It turns out that external whistle-blowing is often the result of an escalating conflict that can be interpreted as a very personal experience of strain.     

Assessing the Influence of Psychosocial and Career Mentoring on Organizational Attractiveness

Past research on mentoring in organizational settings has focused on psychosocial and career mentoring functions more senior employees provide to new hires. In this study, we examined whether the perceived quality of psychosocial and career functions of pre‐hire mentoring and realistic job previews (RJPs) provided to students through mentoring impact organizational attraction and potential applicants' intentions to pursue or accept jobs at their mentors' organization, and ultimately their acceptance of positions with their mentors' organization. We compared face‐to‐face mentoring with online mentoring. A field study was conducted (n=194 European graduate students). Findings indicate that the quality of psychosocial mentoring plays a larger role in organizational attraction and intentions to pursue jobs than the perceived level/quality of career mentoring functions, with RJPs functioning as a suppressor variable. Obtaining a job with the mentors' organization was related to career, but not to psychosocial mentoring functions or RJPs.     

Extracellular amino acid levels in the paraventricular nucleus and the central amygdala in high- and low-anxiety dams rats during maternal aggression: regulation by oxytocin

Brain oxytocin (OT) regulates aspects of emotionality and stress coping including maternal behavior and maternal aggression. Maternal aggression correlates with the amount of OT released within the paraventricular nucleus (PVN) and the central amygdala (CeA). OT, a key neurotransmitter or neuromodulator, is likely to modulate other neurotransmitter systems. Here, we investigated the dynamic changes in extracellular concentrations of the amino acids aspartate, glutamate, gamma-aminobutyric acid (GABA), serine, histidine, arginine and taurine in the PVN and CeA in lactating rats bred for high (HAB) and low (LAB) anxiety-related behavior under basal conditions and during maternal aggression. Further, to determine whether local OT is involved in the regulation of amino acid release we infused a selective OT receptor antagonist (OTA) via local retrodialysis. Within the CeA, HAB and LAB dams differed in the basal release of glutamate and arginine. Infusion of a selective OTA increased the concentrations of glutamate and aspartate in LAB dams and GABA in HAB dams. In OTA-treated HAB and LAB dams taurine levels increased during maternal aggression. Within the PVN, the highly-aggressive HAB dams showed a more pronounced increase in aspartate and serine levels; the latter being attenuated by local OTA administration. However, OTA did not affect the level of any amino acid in the LAB dams. Thus, the extracellular concentrations of selected amino acids differed between lactating HAB and LAB dams under both basal conditions and following maternal aggression. The effects of OT within the CeA and PVN on maternal aggressive behavior might be related to its regulation of local amino acid release.     

Specifying what makes a personal memory unique enhances emotion regulation

During recollection of past experiences, the way autobiographical information is processed affects the intensity of the emotion aroused. Two main hypotheses were proposed in this respect: One focuses on the type of information activated during retrieval; the second is centered on the mode of processing at work. This article defends the notion that both perspectives need to be integrated to predict emotional arousal during autobiographical recollection. The authors explored the consequences on emotional feeling intensity by manipulating the type of information processed, together with the cognitive mode activated (specific vs. general level of processing). Results support previous findings that voluntarily specifying memories reduces emotional intensity. However, this was observed only when the details that make the event unique were processed.     

Temporal parameters and time course of perceptual latency priming

Visual stimuli (primes) reduce the perceptual latency of a target appearing at the same location (perceptual latency priming, PLP). Three experiments assessed the time course of PLP by masked and, in Experiment 3, unmasked primes. Experiments 1 and 2 investigated the temporal parameters that determine the size of priming. Stimulus onset asynchrony was found to exert the main influence accompanied by a small effect of prime duration. Experiment 3 used a large range of priming onset asynchronies. We suggest to explain PLP by the Asynchronous Updating Model which relates it to the asynchrony of 2 central coding processes, preattentive coding of basic visual features and attentional orienting as a prerequisite for perceptual judgments and conscious perception.