Executive functions and social skills in survivors of pediatric brain tumor

Medical advances have resulted in increased survival rates for children with brain tumors. Consequently, issues related to survivorship have become more critical. The use of multimodal treatment, in particular cranial radiation therapy, has been associated with subsequent cognitive decline. Specifically, deficits in executive functions have been reported in survivors of various types of pediatric brain tumor. Survivors are left with difficulties, particularly in self-monitoring, initiation, inhibition, and planning, to name a few. Another domain in which survivors of pediatric brain tumor have been reported to show difficulty is that of social skills. Parents, teachers, and survivors themselves have reported decreased social functioning following treatment. Deficits in executive functions and social skills are likely interrelated in this population, as executive skills are needed to navigate various aspects of social interaction; however, this has yet to be studied empirically. Twenty-four survivors of pediatric brain tumor were assessed using a computerized task of executive functions, as well as paper-and-pencil measures of social skills and real-world executive skills. Social functioning was related to a specific aspect of executive functions, that is, the survivors' variability in response time, such that inconsistent responding was associated with better parent-reported and survivor-reported social skills, independent of intellectual abilities. Additionally, parent-reported real-world global executive abilities predicted parent-reported social skills. The implications of these findings for social skills interventions and future research are discussed.     

A Comparison of the Cross-Sectional and Sequential Designs when Assessing Longitudinal Mediation

Mediational studies are often of interest in psychology because they explore the underlying relationship between 2 constructs. Previous research has shown that cross-sectional designs are prone to biased estimates of longitudinal mediation parameters. The sequential design has become a popular alternative to the cross-sectional design for assessing mediation. This design is a compromise between the cross-sectional and longitudinal designs because it incorporates time in the model but has only 1 measurement each of X, M, and Y. As such, this design follows the recommendation of the MacArthur group approach, which stresses the importance of multiple waves of data for studying mediation. These 2 designs were compared to see whether the sequential design assesses longitudinal mediation more accurately than the cross-sectional design. Specifically, analytic expressions are derived for the bias of estimated direct and indirect effects as calculated from the sequential design when the actual mediational process follows a longitudinal autoregressive model. It was found that, in general, the sequential design does not assess longitudinal mediation more accurately than the cross-sectional design. As a result, neither design can be depended on to assess longitudinal mediation accurately.     

Threat to Whom? Conflict,Consensus, and Social Control

A number of observers have questioned the efficacy of model specifications designed to falsify the conflict perspective of crime control. Exploiting the quasi-experimental qualities of Cincinnati's recent race-related riot, this study employs interrupted time series techniques to evaluate a component of conflict theory, the racial threat hypothesis. In brief, the autoregressive integrated moving average (ARIMA) transfer function models indicate that, upon controlling for the potentially confounding effects of robbery offenses, the April 2001 riot led to a lasting increase in the level of robbery arrests. The implications of this investigation for distinguishing between the predictions of conflict and consensus theories of crime control are discussed.     

The role of perfectionism in cognitive behaviour therapy outcomes for clinically anxious children

The main aim of this study was to determine whether pre-treatment levels of child perfectionism impacted on anxiety treatment outcomes for school-aged children. In addition, it was investigated whether child perfectionism decreased following treatment for anxiety. Participants were sixty-seven clinically anxious children aged 6–13 years (female = 34; majority Caucasian) who were enrolled in a group-based cognitive behaviour therapy program, and their parents. They completed self-report questionnaires on anxiety and depressive symptoms and were administered a diagnostic interview to determine the type and clinician rated severity of anxiety and related disorders pre- and post-treatment and at 6-month follow-up. Self- and parent-rated perfectionism were also measured pre-treatment, while a subset of children completed perfectionism measures post-treatment as well. Self-Oriented Perfectionism, but not Socially Prescribed Perfectionism, predicted poorer self-reported treatment outcome (higher levels of anxiety symptoms) immediately following treatment and at 6-month follow-up when using a multi-informant approach. Additionally, both Self-Oriented and Socially Prescribed child perfectionism significantly reduced immediately following treatment. Despite reductions in child perfectionism following anxiety treatment, higher Self-Oriented Perfectionism may impact negatively on child anxiety treatment outcome.     

Focusing on Patient Needs and Preferences May Improve Genetic Counseling for Colorectal Cancer

During cancer genetic counseling, different items which counselors consider important are discussed. However, relatively little empirical evidence exists regarding the needs and preferences of counselees. In this study needs and preferences were assessed from counselees with a personal and/or family history of colorectal cancer (CRC), who were referred for genetic counseling regarding CRC. They received a slightly modified version of the QUOTE-GENE^ca questionnaire prior to their first visit to the Hereditary Cancer Clinic. Response rate was 60 % (48/80 participants). Counselees rated the importance of 45 items assessing their needs and preferences regarding the content and process of genetic counseling. Participants rated the items regarding discussion of information about their familial CRC risk (100 %) and preventive options (98 %) as important or very important. Fewer participants rated items concerning general information on genetics as important. Sensitive communication during counseling was considered very important by a large percentage of counselees. Generally, no major differences were seen between participants in relation to individual characteristics. Our data suggest that focusing on familial CRC risk and surveillance options, in combination with sensitive communication may lead to better satisfaction with genetic counseling.     

Acceptance of Genetic Counseling and Testing in a Hospital-Based Series of Patients with Gynecological Cancer

Referral of patients with endometrial (EC) and/or ovarian cancer (OC) for genetic counseling is based on age at diagnosis and family history. Many patients with hereditary cancers are missed by following this strategy. We determined acceptance and mutation detection rate of offering genetic counseling and testing to unselected EC and OC patients. Therefore, in 2007, EC and OC patients were invited for genetic counseling and testing. Patients were asked for their reasons to accept or decline. Nineteen out of fifty-two EC patients (36 %) and twenty-two out of thirty-five OC patients (63 %) accepted genetic counseling, mainly to receive risk assessment for themselves and relatives. Counseling was declined mainly because patients did not want more tests or had no relatives for whom it was relevant. Eighteen out of nineteen EC patients (95 %) and twenty out of twenty-two OC patients (91 %) underwent genetic testing. One EC patient carried an MSH6 mutation (mutation detection rate: 6 %). BRCA1/2 mutations were found in two out of twenty OC patients (10 %). Eleven patients (29 %) received surveillance recommendations for themselves and their relatives. Finally, family history recorded by the gynecologist was compared to that taken by the clinical geneticist. Gynecologists reported family history in ten out of forty-one participants (24 %). In conclusion, genetic counseling and testing are acceptable to patients with OC and/or EC. The 10 % BRCA1/2 mutation detection rate and underreporting of family history by gynecologists warrant referral for genetic counseling for all OC patients, followed by BRCA1/2 testing if indicated. We recommend that microsatellite instability and immunohistochemical analysis be performed in all EC patients, followed by genetic counseling if appropriate. These strategies will lead to better cancer prevention in gynecological cancer patients and their relatives.     

Construing a “Perfect Knight”: A Personal Construct Investigation of Mass Murder

We report three studies in which we examined the structure of interpersonal construct systems. We attempted to identify (a) the degree to which individuals' differentiation in the constructs they used to construe themselves paralleled the differentiation in the constructs they used to construe other and (b) the differences and similarities in the content of constructs used by subjects to construe themselves, liked peers, and disliked peers. In addition, we compared the content of the liked- and disliked-peer constructs with those used by employees construing co-workers in a previous study. Findings indicated that Ziller, Martell, and Morrison's (1977) checklist measure of self differentiation was weakly correlated in the first sample and uncorrelated in the second sample with Crockett's (1965) Role Category Questionnaire (RCQ), a measure of other differentiation. Differentiation scores from the other and self versions of the RCQ were moderately correlated. Content analyses revealed that self constructs were drawn largely from the same pool as those used in describing liked and disliked peers; they were more similar to the liked-peer constructs than the disliked-peer ones, but also drew heavily on the disliked-peer construct pool. Constructs used to describe liked and disliked peers were very similar to those used to describe co-workers but were clearly influenced by context. To account for the findings, we suggest that constructs become meaningful and thus prominent in a particular domain because of their usefulness for the particular construal tasks encountered in that domain.     

Mechanisms for the Relationship between Traditional Masculine Ideologies and Rape Myth Acceptance Among College Men

We explored mechanisms for the relationship between traditional masculine ideologies and rape myth acceptance. We hypothesized that locus of control would serve as a mediator for victim precipitation rape myths, and negative attitudes toward women would serve as a mediator for victim masochism and victim fabrication rape myths. Using a sample of 100 male college students, the results indicated that negative attitudes toward women mediated the relationship between traditional masculine ideologies and all 3 types of rape myths, but locus of control did not serve as a mediator for any. Implications and directions for future research are discussed.     

Short- and Long-Term Implicit Memory in Aging and Alzheimer's Disease

ABSTRACT

Implicit memory processes were investigated via picture naming in healthy young and older adults and in persons with mild Alzheimer's disease (AD). Repetition priming in picture-naming was intact in all groups over the course of a short retention interval (seconds), and only the AD group revealed a deficit over a longer interval (72 hours). In addition, the AD group showed impaired procedural memory, with no benefit of practice on picture-naming. Impaired long-term priming was related to severity of AD. Both theoretical and methodological implications are discussed.