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131.
Evidence for a gene-environment interaction in predicting behavioral inhibition in middle childhood 总被引:8,自引:0,他引:8
Fox NA Nichols KE Henderson HA Rubin K Schmidt L Hamer D Ernst M Pine DS 《Psychological science》2005,16(12):921-926
Gene-environment interactions are presumed to shape human behavior during early development. However, no human research has demonstrated that such interactions lead to stable individual differences in fear responses. We tested this possibility by focusing on a polymorphism in the promoter region of the gene for the serotonin transporter (5-HTT). This polymorphism has been linked to many indices of serotonin activity. Specifically, we tested the hypothesis that an interaction between children's 5-HTT status and maternal reports of social support predicts inhibited behavior with unfamiliar peers in middle childhood. Results were consistent with this hypothesis: Children with the combination of the short 5-HTT allele and low social support had increased risk for behavioral inhibition in middle childhood. 相似文献
132.
Researchers working on children's moral understanding maintain that the child's capacity to distinguish morality from convention shows that children regard moral violations as objectively wrong (e.g. Nucci, L. (2001). Education in the moral domain. Cambridge: Cambridge University Press). However, one traditional way to cast the issue of objectivism is to focus not on conventionality, but on whether moral properties depend on our responses, as with properties like icky and fun. This paper argues that the moral/conventional task is inadequate for assessing whether children regard moral properties as response-dependent. Unfortunately, children's understanding of response-dependent properties has been neglected in recent research. Two experiments are reported showing that children are more likely to treat properties like fun and icky as response-dependent than moral properties like good and bad. Hence, this helps support the claim that children are moral objectivists. 相似文献
133.
134.
Chronic exposure to mild unpredictable stress has been found to depress the consumption of, and preference for, highly palatable sucrose solution in rats. Stress-induced behavioral deficits may be maintained for a long time, however chronic administration of clinically effective antidepressants can restore normal behavior. This is the first report showing that Sprague-Dawley rats can be used in this model. A preference deficit in this strain of rats took at least 7 weeks to develop; about twice the time required when hooded Lister or Wistar rats are used in this model. Water consumption was not effected by chronic exposure to the mild stress regime and/or by chronic administration of the selective serotonin (5-HT) releasing agent MMAI (5-methoxy-6-methyl-2-aminoindan). The stress-induced deficit in sucrose intake was completely reversed by chronic treatment with MMAI (5 mg/kg, 2 x day) over 3 weeks in the two-bottle tests. In single-bottle tests, chronic treatment with the selective 5-HT releasers, MMAI (5 mg/kg, 2 x day) or MTA (p-methylthioamphetamine; 5 mg/kg, 2 x day), reversed the deficit in rewarded behavior (anhedonia) measured as a decrease in the consumption of 1% sucrose solution in the chronic mild stress model of depression in rats. With the experimental procedure employed, and at a dose of 10 mg/kg/day of 5-HT releasers, the magnitude and onset of this effect were greater than observed following similar administration of the selective 5-HT reuptake inhibitor (SSRI) sertraline (10 mg/kg/day), used as a standard anti-depressant drug. 相似文献
135.
To date, applications of automated assessment techniques in personality testing have largely been limited to objective personality instruments with text stimuli; few assessment applications have involved graphic stimuli. Although projective personality instruments generally include ambiguous graphic or pictorial stimuli, computer applications with these procedures have been limited to automated scoring and interpretation, administration of sentence completion devices employing text stimuli, and the use of mechanical methods rather than computer graphics to display visual stimuli. In the present report, we describe a Macintosh HyperCard application for administering an objective personality test with visual stimuli, the Barron-Welsh Revised Art Scale of the Welsh Figure Preference Test. This test consists of a series of figural stimuli and a binary “like”/“dislike” response format, and it thus represents an administration procedure between standard objective self-report inventories involving text stimuli and a “true”/“false” response or variant, and tests such as the Rorschach or TAT that are both figural and free-response. The HyperCard language provides a variety of promising techniques useful for microcomputer test administration. 相似文献
136.
In his paper entitled “Ethics and the Funding of Research and Development at Universities”1 Spier examines some of the potential problems of the relationship between 1) corporate sponsors of research and 2) the universities
(and faculty) that receive that funding. Citing “He who pays the piper, calls the tune,” Spier suggests that a better way
of funding research would be to “set up a dedicated publicly sponsored research establishment” with the stated goal of achieving
particular technical or engineering objectives. (Spier cited the successful Animal Virus Research of the UK as an example).
Spier states that researchers at these establishments are “not subjected to the triple requirement to teach, research and
administer as are university members, so they do not have to face the same ethical challenges of the academics.” This paper
will examine the stated dangers of public/corporate research partnerships and whether the proposed alternative shares equally
troubling ethical issues. 相似文献
137.
Nichols DS 《Journal of personality assessment》1996,67(3):516-528
An impressionistic list of methodological considerations that may be of consequence in Minnesota Multiphasic Personality Inventory (MMPI)-Rorschach studies is presented. These include the potential effects of the multidimensionality of the basic clinical MMPI scales in comparison studies, issues of deception and response style in such studies, and the rote of theory in guiding the selection of variables in the search for MMPI-Rorschach correspondences. The recently established necessity of controls for the total number of Rorschach responses provides the basis for suggestions for further controls in MMPI-Rorschach studies, including those for level of distress and for the minimization/exaggeration of psychopathology. An effort is made to contrast these two instruments in terms borrowed from information theory as a way of illuminating their complementary aspects, and suggesting means by which each may contribute to an enhanced understanding of the other. 相似文献
138.
139.
Goal attribution in chimpanzees 总被引:1,自引:0,他引:1
Does the chimpanzee attribute goals to others? Recent infant studies using the looking time measure have been interpreted as evidence that human infants attribute goals. An experiment modeled on these studies was carried out on chimpanzees, and the chimpanzees responded the way infants do. This indicates that chimpanzees also attribute goals and hence that this capacity is not distinctively human. 相似文献
140.
Kristine Klussman Austin Lee Nichols Julia Langer 《International journal of psychology》2021,56(6):834-842
People who have meaningful lives generally experience less anxiety and depression. Meaning salience, or the awareness of the meaning in one's life, is believed to partially explain this relationship. However, in times of isolation, what might be most salient to people are the meaningful aspects of their lives that have disappeared. This study seeks to understand how making gained versus lost meaning salient affects anxiety and depression. Participants either wrote for 5 minutes about how their life gained meaning (n = 29) or lost meaning (n = 30) due to the coronavirus restrictions, or about music (i.e., the control condition; n = 32). Those who wrote about gained meaning experienced less momentary anxiety than those who wrote about lost meaning. In addition, meaning salience moderated the relationship between meaning and both anxiety and depression. Those who wrote about gained meaning appeared to exhibit a positive relationship between meaning in life (MIL) and both anxiety and depression, while those who wrote about lost meaning exhibited negative relationships. In all, this suggests that meaning salience is not always positive and that researchers and practitioners should consider how making positive meaning salient may be more beneficial than a general focus on MIL. 相似文献