Overt naming fMRI pre- and post-TMS: Two nonfluent aphasia patients, with and without improved naming post-TMS

Two chronic, nonfluent aphasia patients participated in overt naming fMRI scans, pre- and post-a series of repetitive transcranial magnetic stimulation (rTMS) treatments as part of a TMS study to improve naming. Each patient received 10, 1-Hz rTMS treatments to suppress a part of R pars triangularis. P1 was a ‘good responder’ with improved naming and phrase length; P2 was a ‘poor responder’ without improved naming.Pre-TMS (10 years poststroke), P1 had significant activation in R and L sensorimotor cortex, R IFG, and in both L and R SMA during overt naming fMRI (28% pictures named). At 3 mo. post-TMS (42% named), P1 showed continued activation in R and L sensorimotor cortex, R IFG, and in R and L SMA. At 16 mo. post-TMS (58% named), he also showed significant activation in R and L sensorimotor cortex mouth and R IFG. He now showed a significant increase in activation in the L SMA compared to pre-TMS and at 3 mo. post-TMS (p < .02; p < .05, respectively). At 16 mo. there was also greater activation in L than R SMA (p < .08). At 46 mo. post-TMS (42% named), this new LH pattern of activation continued. He improved on the Boston Naming Test from 11 pictures named pre-TMS, to scores ranging from 14 to 18 pictures, post-TMS (2–43 mo. post-TMS). His longest phrase length (Cookie Theft picture) improved from three words pre-TMS, to 5–6 words post-TMS.Pre-TMS (1.5 years poststroke), P2 had significant activation in R IFG (3% pictures named). At 3 and 6 mo. post-TMS, there was no longer significant activation in R IFG, but significant activation was present in R sensorimotor cortex. On all three fMRI scans, P2 had significant activation in both the L and R SMA. There was no new, lasting perilesional LH activation across sessions for this patient. Over time, there was little or no change in his activation. His naming remained only at 1–2 pictures during all three fMRI scans. His BNT score and longest phrase length remained at one word, post-TMS.Lesion site may play a role in each patient’s fMRI activation pattern and response to TMS treatment. P2, the poor responder, had an atypical frontal lesion in the L motor and premotor cortex that extended high, near brain vertex, with deep white matter lesion near L SMA. P2 also had frontal lesion in the posterior middle frontal gyrus, an area important for naming (Duffau et al., 2003); P1 did not. Additionally, P2 had lesion inferior and posterior to Wernicke’s area, in parts of BA 21 and 37, whereas P1 did not.The fMRI data of our patient who had good response following TMS support the notion that restoration of the LH language network is linked in part, to better recovery of naming and phrase length in nonfluent aphasia.     

In‐group reassurance in a pain setting produces lower levels of physiological arousal: direct support for a self‐categorization analysis of social influence

A large body of research demonstrates a strong social component to people's pain experiences and pain‐related behaviours. We investigate this by examining the impact of social‐influence processes on laboratory‐induced pain responses by manipulating the social‐categorical relationship between the person experiencing pain and another who offers reassurance. We show that physiological arousal associated with laboratory‐induced pain is significantly lower in normal, healthy participants following reassurance about the pain‐inducing activity when that reassurance comes from an in‐group member in contrast to reassurance from an out‐group member and a no reassurance control. These data are consistent with predictions derived from self‐categorization theory, providing convincing empirical support of its analysis of social influence using a non‐reactive measure. These data also represent a clear advance within the pain literature by identifying a possible common process to the social‐psychological component of pain responses. Copyright © 2006 John Wiley & Sons, Ltd.     

Changes in attitudes towards war and violence after September 11, 2001

Two inter-related studies examined the effect of the September 11, 2001, terrorist attacks on attitudes towards war and violence. A three-wave between-subjects analysis revealed that attitudes towards war became more positive after September 11, 2001 and remained high over a year afterwards. Self-reported trait physical aggression also rose after September 11. Attitudes towards penal code violence (PCV) became more positive immediately after September 11, but were somewhat reduced a year afterward. A two-wave within subjects study revealed that war attitudes became even more positive at 2 months post-September 11. Attitudes towards PCV became less positive during this time period, but only for women. Other aggression-related attitudes were not affected in either study. These studies demonstrate that a large-scale event can change attitudes, but those attitudes must be directly relevant to the event.     

Community Mental Health Service Providers' Codes of Ethics and the Standards for Educational and Psychological Testing

This study compared the codes of ethics of 13 professional organizations for community mental health service providers that have been represented at the meetings of the Fair Access Coalition for Testing with the Standards for Educational and Psychological Testing (American Educational Research Association [AERA], American Psychological Association [APA], & National Council on Measurement in Education [NCME], 1985) and all those standards cited in the revised Standards (AERA, APA, & NCME, 1999) that the investigators identified as pertaining to clinical assessment, as these standards apply to test users. The results suggest that only 2 of the codes of ethics address many of the Standards. Implications and recommendations for professional organizations are provided.     

Empirical evaluation and justification of methodologies in psychological science.

The purpose of this article is to describe a relatively new movement in the history and philosophy of science, naturalism, a form of pragmatism emphasizing that methodological principles are empirical statements. Thus, methodological principles must be evaluated and justified on the same basis as other empirical statements. On this view, methodological statements may be less secure than the specific scientific theories to which they give rise. The authors examined the feasibility of a naturalistic approach to methodology using logical and historical analysis and by contrasting theories that predict new facts versus theories that explain already known facts. They provide examples of how differences over methodological issues in psychology and in science generally may be resolved using a naturalistic, or empirical, approach.     

On the heritability of inspection time and its covariance with IQ: a twin study

Using the classical twin design, this study investigates the influence of genetic factors on the large phenotypic variance in inspection time (IT), and whether the well established IT–IQ association can be explained by a common genetic factor. Three hundred ninety pairs of twins (184 monozygotic, MZ; 206 dizygotic, DZ) with a mean age of 16 years participated, and 49 pairs returned approximately 3 months later for retesting. As in many IT studies, the pi figure stimulus was used and IT was estimated from the cumulative normal ogive. IT ranged from 39.4 to 774.1 ms (159±110.1 ms) with faster ITs (by an average of 26.9 ms) found in the retest session from which a reliability of .69 was estimated. Full-scale IQ (FIQ) was assessed by the Multidimensional Aptitude Battery (MAB) and ranged from 79 to 145 (111±13). The phenotypic association between IT and FIQ was confirmed (−.35) and bivariate results showed that a common genetic factor accounted for 36% of the variance in IT and 32% of the variance in FIQ. The maximum likelihood estimate of the genetic correlation was −.63. When performance and verbal IQ (PIQ & VIQ) were analysed with IT, a stronger phenotypic and genetic relationship was found between PIQ and IT than with VIQ. A large part of the IT variance (64%) was accounted for by a unique environmental factor. Further genetic factors were needed to explain the remaining variance in IQ with a small component of unique environmental variance present. The separability of a shared genetic factor influencing IT and IQ from the total genetic variance in IQ suggests that IT affects a specific subcomponent of intelligence rather than a generalised efficiency.     

On the Strategic Weighting of Spectral Information in Consonant Identification

When identifying speech sounds, do listeners direct attention specifically to those frequency regions in which distinctive phonetic information is located? Scharf, Dai, and Miller (1988) concluded that they do, based on an experiment that involved listeners identifying the members of a pair of voiced stop consonants differing primarily in their third-formant transitions. Adding extra contrastive acoustic energy to the third-formant region of one of the consonants enhanced performance more than did adding energy to a region where the consonants were otherwise identical. The present experiments extended this paradigm to reveal evidence of an interaction between the frequency region in which extra distinctive energy was added and the class of consonant to which it was added. The results were more consistent with an account in terms of the effects of added energy on phonetic identity than one based on spectral selective attention.