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21.
Amyotrophic Lateral Sclerosis is a neurodegenerative disorder characterized primarily by motor network disruption. Extra-motor manifestations including executive functions, social cognition, and behavioral changes are now well recognized as important features of ALS, and are associated with frontotemporal and frontostriatal network disruption. However, the presence and characterization of language changes has received less attention. This systematic review characterizes the profile of reported language dysfunction in ALS. PRISMA guidelines were implemented to carry out and report the review. Current evidence suggests that areas of neuroanatomical disruption in ALS spread to language centers such as posterior, inferior frontal and superior temporal areas leading to deficits in word retrieval, syntactic and grammatical processing, and spelling. However, the majority of studies of language in ALS have been limited by the recruitment of small clinic-based prevalent samples and important questions remain regarding the incidence and progression of language impairment in ALS. Further studies from population-based incident cohorts will help to determine the range of language deficits in ALS, and how these relate to previously defined executive and behavioral sub-phenotypes. 相似文献
22.
Although perceiving that social support is available is often associated with psychological benefits in times of stress, there is evidence that actually receiving support is associated with increased distress. To assess whether this latter association could be spurious, the authors conducted computer simulation studies to examine two theoretical models that could give rise to it. Study 1 examined a process whereby distress leads to provision of support rather than the reverse. Study 2 examined a process whereby an adverse event increases both support and distress. In both cases, substantial spurious associations were produced only when parameter values were markedly unrealistic. It was concluded that these possible sources of spuriousness are insufficient to explain the association between support and distress found in naturalistic studies. 相似文献
23.
Rafaeli E Cranford JA Green AS Shrout PE Bolger N 《Personality & social psychology bulletin》2008,34(12):1703-1718
The authors examined the effects of social hindrance and support on negative and positive relationship-specific feelings in three daily diary studies. Study 1 showed that hindrance and support independently predicted positive relationship feelings, but only hindrance predicted negative feelings. Study 2 used new measures of hindrance and support and showed that hindrance and support independently predicted same-day relationship feelings but that the effects of hindrance were stronger in magnitude. Study 3 yielded similar findings using the new measures of hindrance and support and controlling for morning feeling. These asymmetrical crossover effects suggest that bad is only stronger than good when it comes to bad outcomes; they also support the distinction between aversive and appetitive relational processes. 相似文献
24.
Spatial knowledge acquisition from maps and from navigation in real and virtual environments 总被引:9,自引:0,他引:9
In this study, the nature of the spatial representations of an environment acquired from maps, navigation, and virtual environments (VEs) was assessed. Participants first learned the layout of a simple desktop VE and then were tested in that environment. Then, participants learned two floors of a complex building in one of three learning conditions: from a map, from direct experience, or by traversing through a virtual rendition of the building. VE learners showed the poorest learning of the complex environment overall, and the results suggest that VE learners are particularly susceptible to disorientation after rotation. However, all the conditions showed similar levels of performance in learning the layout of landmarks on a single floor. Consistent with previous research, an alignment effect was present for map learners, suggesting that they had formed an orientation-specific representation of the environment. VE learners also showed a preferred orientation, as defined by their initial orientation when learning the environment. Learning the initial simple VE was highly predictive of learning a real environment, suggesting that similar cognitive mechanisms are involved in the two learning situations. 相似文献
25.
Properties of cognitive maps constructed from texts 总被引:2,自引:0,他引:2
Subjects in three experiments read texts describing the locations of landmarks in a fictitious town. Later they drew sketch maps and verified sentences describing the relative locations of the landmarks. We predicted that subjects would develop mental models of the town that were organized around important landmarks (“anchors”), as are cognitive maps constructed through real-world navigation. More specifically, we expected that landmarks used in the text as reference points for describing the locations of some other landmarks would emerge as anchors in the subjects’ cognitive maps and would consequently be recalled more accurately. Results showed that subjects represented such reference-point landmarks more accurately than they did the locations of other landmarks. This effect was independent of: (1) the perspective from which the text was written (route or survey); (2) whether or not a map was present at learning; (3) the order of information in the text (linear or anchors-first), and (4) the amount of information available to the subjects while drawing sketch maps (the full text, the landmark names only, or no information). 相似文献
26.
Personality and the Problems of Everyday Life: The Role of Neuroticism In Exposure and Reactivity to Daily Stressors 总被引:12,自引:0,他引:12
This article investigates mechanisms through which neuroticism leads to distress in daily life. Neuroticism may lead to distress through exposing people to a greater number of stressful events, through increasing their reactivity to those events, or through a mechanism unrelated to environmental events. This article evaluates the relative importance of these three explanations. Subjects were 339 persons who provided daily reports of minor stressful events and mood for 6 weeks. Exposure and reactivity to these minor stressors explained over 40% of the distress difference between high- and low-neuroticism subjects. Reactivity to stressors accounted for twice as much of the distress difference as exposure to stressors. These results suggest that reactions within stressful situations are more important than situation selection in explaining how neuroticism leads to distress in daily life. 相似文献
27.
Multicriteria decision making (MCDM) methods generally require information that is difficult and expensive to obtain. It is shown in this paper that given an ordering of criteria by importance, and whether each alternative is above the average evaluation of the alternatives for each criterion, considerable information can be extracted concerning the overall rankings of the alternatives. This is done by recognizing the similarity between criteria in MCDM, and voters in social choice theory. Multicriteria approval, proposed in this paper, is an MCDM adaptation of approval voting which can be used to classify decisions into one of several categories, depending on whether, and the manner in which, a superior alternative can be identified. An exhaustive examination of all possible decision situations of tractable size is made to measure the applicability of multicriteria approval, and the approach is demonstrated in an industrial procurement case. In addition to requiring minimal information from a decision maker, multicriteria approval satisfies several desirable criteria for MCDM techniques. © 1998 John Wiley & Sons, Ltd. 相似文献
28.
Cranford JA Shrout PE Iida M Rafaeli E Yip T Bolger N 《Personality & social psychology bulletin》2006,32(7):917-929
The recent growth in diary and experience sampling research has increased research attention on how people change over time in natural settings. Often however, the measures in these studies were originally developed for studying between-person differences, and their sensitivity to within-person changes is usually unknown. Using a Generalizability Theory framework, the authors illustrate a procedure for developing reliable measures of change using a version of the Profile of Mood States (POMS; McNair, Lorr, & Droppleman, 1992) shortened for diary studies. Analyzing two data sets, one composed of 35 daily reports from 68 persons experiencing a stressful examination and another composed of daily reports from 164 persons over a typical 28-day period, we demonstrate that three-item measures of anxious mood, depressed mood, anger, fatigue, and vigor have appropriate reliability to detect within-person change processes. 相似文献
29.
Mediation in experimental and nonexperimental studies: new procedures and recommendations 总被引:9,自引:0,他引:9
Mediation is said to occur when a causal effect of some variable X on an outcome Y is explained by some intervening variable M. The authors recommend that with small to moderate samples, bootstrap methods (B. Efron & R. Tibshirani, 1993) be used to assess mediation. Bootstrap tests are powerful because they detect that the sampling distribution of the mediated effect is skewed away from 0. They argue that R. M. Baron and D. A. Kenny's (1986) recommendation of first testing the X --> Y association for statistical significance should not be a requirement when there is a priori belief that the effect size is small or suppression is a possibility. Empirical examples and computer setups for bootstrap analyses are provided. 相似文献
30.
In this review we consider the new science of Darwinian medicine. While it has often been said that evolutionary theory is
the glue that holds the disparate branches of biological inquiry together and gives them direction and purpose, the links
to biomedical inquiry have only recently been articulated in a coherent manner. Our aim in this review is to make clear first
of all, how evolutionary theory is relevant to medicine; and secondly, how the biomedical sciences have enriched our understanding
of evolutionary processes. We will conclude our review with some observations of the philosophical significance of this interplay
between evolutionary theory and the biomedical sciences. 相似文献