Varenicline-induced mixed mood and psychotic episode in a patient with a past history of depression

Varenicline is a promising agent with demonstrated efficacy in the promotion of smoking cessation. However, from the time of initial trials, it has been associated with significant psychiatric adverse effects. We describe a case where mixed mood and psychotic disturbance developed in an individual with a history of depression and a family history of bipolar disorder. Based on this case, we hypothesize a possible mechanism of action for these adverse effects and preventive measures that could be undertaken in its effective use.     

The relationship between biological and psychosocial risk factors and resting‐state functional connectivity in 2‐month‐old Bangladeshi infants: A feasibility and pilot study

Childhood poverty has been associated with structural and functional alterations in the developing brain. However, poverty does not alter brain development directly, but acts through associated biological or psychosocial risk factors (e.g. malnutrition, family conflict). Yet few studies have investigated risk factors in the context of infant neurodevelopment, and none have done so in low‐resource settings such as Bangladesh, where children are exposed to multiple, severe biological and psychosocial hazards. In this feasibility and pilot study, usable resting‐state fMRI data were acquired in infants from extremely poor (n = 16) and (relatively) more affluent (n = 16) families in Dhaka, Bangladesh. Whole‐brain intrinsic functional connectivity (iFC) was estimated using bilateral seeds in the amygdala, where iFC has shown susceptibility to early life stress, and in sensory areas, which have exhibited less susceptibility to early life hazards. Biological and psychosocial risk factors were examined for associations with iFC. Three resting‐state networks were identified in within‐group brain maps: medial temporal/striatal, visual, and auditory networks. Infants from extremely poor families compared with those from more affluent families exhibited greater (i.e. less negative) iFC in precuneus for amygdala seeds; however, no group differences in iFC were observed for sensory area seeds. Height‐for‐age, a proxy for malnutrition/infection, was not associated with amygdala/precuneus iFC, whereas prenatal family conflict was positively correlated. Findings suggest that it is feasible to conduct infant fMRI studies in low‐resource settings. Challenges and practical steps for successful implementations are discussed.     

A Pilot Study Exploring PTSD Symptom Clusters as Mediators between Trauma Exposure and Attachment Behaviors in Married Adults

The purpose of this pilot study was to examine the mediating effect of posttraumatic stress disorder (PTSD) symptom clusters on the association between trauma exposure and attachment behaviors. Results from bootstrapped mediation analyses with a sample of 116 married adults revealed that total PTSD, avoidance, negative alterations in cognition/mood, and arousal symptoms partially mediated the effect of trauma exposure on perceived attachment behaviors in men only; the intrusion symptom cluster was not significant and there were no significant mediation effects for women. Findings shed light on possible gender variant mechanisms by which trauma may threaten secure attachment bonds in couples.     

Teleology and Structural Directedness

This paper examines the argument that scientific thinkers who embrace a religious tradition can promote intellectual integration between religion and science rather than fragmented discourse. It is argued that God’s Word as an event and the concept of structural directedness, an organized movement toward a future that does not demand a consciously intended end, may be helpful in understanding God’s actions in an indeterminant way.     

It Is Time to Observe the Creative Process: How to Use a Creative Process Report Diary (CRD)

Although the first research on the creative process was based on interviews with the aim of identifying the main stages (macro‐process), in the last 50 years researchers have focused more on the analysis of micro‐processes, i.e., the mechanisms underlying the generation of ideas. This interest in the micro‐processes is partly a result of the tools available to researchers to carry out rigorous studies on the creative process. In this article, we present a useful and relevant analytical tool for macro‐processes to assess the creative process in a natural context and when it occurs. Here, the reader will find advice on establishing a research protocol for the creative process by using diaries. Examples of diaries and results are presented. The advantage of this tool is that it enables a direct, rich, and inexpensive assessment of the creative process. Thus, the ecological validity of the diary method is particularly high.     

The influence of T-shirt graphics on perceptions and behavioral intentions

Do graphics on clothing drive perceptions? We used a between group design to test if athletic, academic, or suggestive graphics on clothing differentially influence perceptions and behavioral intentions. In study 1, participants (N = 199) rated five female t-shirt models, and in study 2 and 3, participants rated five male t-shirt models (N = 120) or university students (N = 50). Analyses of variance controlling for sex (ANCOVA) showed participants were least likely to want to interact with models/students wearing sexually suggestive graphics: Study 1, F(3,165) = 30.263, p < .001, η_p ²  = .30, power = 1.00; Study 2, F (3,119) = 11.630, p < .000, η_p ² = .234, and Study 3, F(1, 42) = 12.578, p < .000. Participants did not rate models in the academic and athletic graphic shirts differently from models with plain white shirts. Results support the concept that people form different perceptions based upon the clothing a person wears, changing behavioral intentions. Neither sex role ideation (Study 1) or sexism (Study 2) were significant covariates of perceptions and intentions.     

The effects of transcranial direct current stimulation (tDCS) on multitasking performance and oculometrics

Multitasking is the ability to perform more than one task simultaneously. The need to multitask is common in many industries especially within the military with tasks such as air traffic controllers, cyber defense operators and image analysts. However, as the time on task increases, information throughput can become overwhelming resulting in a performance decrement. Through task prioritizing, the operator is able to maintain performance on specific subtasks in which they selected as high importance while other subtasks experience a decrement. The objective of this study was to evaluate the effects of transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal cortex (ldLPFC) on information processing capabilities to improve individual and overall multitasking performance while performing the multi-attribute task battery (MATB). Two groups of 8 participants each received either 2 mA of anodal or sham tDCS while performing MATB. In addition, eye tracking was implemented to record eye movement patterns. In doing so, we were able to determine how much time the operator allocated to each of the subtasks within MATB and how their task priorities changed as workload demands increased. The findings provided evidence that 2 mA of anodal tDCS during MATB significantly improved overall information throughput compared to the sham group. With respect to the individual subtasks, communication and system monitoring displayed the greatest enhancement with anodal tDCS. Our data suggests that tDCS could be a useful tool to enhance information processing capabilities during a multitasking paradigm resulting in improved processing capabilities and information throughput.     

Organizational factors related to attracting job seekers higher in hardiness

Building an organization of workers who thrive in demanding environments begins with recruitment of workers with personality traits predictive of resilience. We integrate fit theories to determine how job advertisement information may attract job seekers higher in psychological hardiness (sense of control, feelings of commitment to many things in life, perceptions of challenge). Across two studies, we manipulated hypothetical job advertisements that were presented to current workers seeking new employment. Job seekers higher in hardiness were more attracted to working with hardy coworkers, less attracted to coping resources, and more attracted to high emotional labor demands compared to job seekers lower in hardiness. A discussion for how organizations may craft job advertisement content to improve their recruitment efforts is provided.     

The impact of individual trauma symptoms of deployed soldiers on relationship satisfaction.

Research traditionally has focused on the development of individual symptoms in those who experienced trauma directly but has overlooked the interpersonal impact of trauma. The current study reports data from 45 male Army soldiers who recently returned from a military deployment to Iraq (Operation Iraqi Freedom) or Afghanistan (Operation Enduring Freedom) and their female spouses/partners. The results indicated that increased trauma symptoms, particularly sleep problems, dissociation, and severe sexual problems, in the soldiers significantly predicted lower marital/relationship satisfaction for both soldiers and their female partners. The results suggest that individual trauma symptoms negatively impact relationship satisfaction in military couples in which the husband has been exposed to war trauma.