What is Genetic Information,and why is it Significant? A Contextual,Contrastive, Approach

abstract Is genetic information of special ethical significance? Does it require special regulation? There is considerable contemporary debate about this question (the ‘genetic exceptionalism’ debate). ‘Genetic information’ is an ambiguous term and, as an aid to avoiding conflation in the genetic exceptionalism debate, a detailed account is given of just how and why ‘genetic information’ is ambiguous. Whilst ambiguity is a ubiquitous problem of communication, it is suggested that ‘genetic information’ is ambiguous in a particular way, one that gives rise to the problem of ‘significance creep’ (i.e., where claims about the significance of certain kinds of genetic information in one context influence our thinking about the significance of other kinds of genetic information in other contexts). A contextual and contrastive methodology is proposed: evaluating the significance of genetic information requires us to be sensitive to the polysemy of ‘genetic information’ across contexts and then examine the contrast in significance (if any) of genetic, as opposed to nongenetic, information within contexts. This, in turn, suggests that a proper solution to the regulatory question requires us to pay more attention to how and why information, and its acquisition, possession and use, come to be of ethical significance.     

Generation and context memory

Generation enhances memory for occurrence but may not enhance other aspects of memory. The present study further delineates the negative generation effect in context memory reported in N. W. Mulligan (2004). First, the negative generation effect occurred for perceptual attributes of the target item (its color and font) but not for extratarget aspects of context (location and background color). Second, nonvisual generation tasks with either semantic or nonsemantic generation rules (antonym and rhyme generation, respectively) produced the same pattern of results. In contrast, a visual (or data-driven) generation task (letter transposition) did not disrupt context memory for color. Third, generating nonwords produced no effect on item memory but persisted in producing a negative effect on context memory for target attributes, implying that (a) the negative generation effect in context memory is not mediated by semantic encoding, and (b) the negative effect on context memory can be dissociated from the positive effect on item memory. The results are interpreted in terms of the processing account of generation. The original, perceptual-conceptual version of this account is too narrow, but a modified processing account, based on a more generic visual versus nonvisual processing distinction, accommodates the results.     

Emotional expressions forecast approach-avoidance behavior

The contention that basic behavioral intentions are forecasted by emotional expressions has received surprisingly little empirical support. We introduce a behavioral task that gauges the speed with which movement of angry and fearful faces (toward or away from an expressor's gaze) are accurately detected. In two studies we found that perceivers were faster to correctly detect approaching anger faces (i.e., faces that moved in the direction of their own gaze). The opposite, however, was not true for fear expressions. These findings offer evidence that, at least for anger displays, the basic behavioral intent to approach is strongly transmitted and at very low-levels of processing, even priming congruent behavioral responses in observers. The null results for fear faces may indicate that these signal a “freezing” response or behavioral inhibition rather than flight per se. The results of this work are discussed in relation to contemporary theories of emotion.     

Large-scale investigation of the role of trait activation theory for understanding assessment center convergent and discriminant validity

This study used trait activation theory as a theoretical framework to conduct a large-scale test of the interactionist explanation of the convergent and discriminant validity findings obtained in assessment centers. Trait activation theory specifies the conditions in which cross-situationally consistent and inconsistent candidate performances are likely to occur. Results obtained by aggregating correlations across 30 multitrait-multimethod matrices supported the propositions of trait activation theory, shedding a more positive light on the construct validity puzzle in assessment centers. Overall, convergence among assessment center ratings was better between exercises that provided an opportunity to observe behavior related to the same trait, and discrimination among ratings within exercises was generally better for dimensions that were not expressions of the same underlying traits. Implications for assessment center research and practice are discussed.     

Relation of game location and experience on mood states

The study investigated relationships between game location, performers' experience, and mood states. 31 experienced collegiate soccer players completed the Brunel Mood Scale to assess anger, calmness, confusion, depression, fatigue, happiness, tension, and vigor before eight competitive games (four home and four away). Participants were categorized into Experienced and Less Experienced groups, based on the level of performance at which they played. Repeated-measures multivariate analyses of variance compared mean mood scores across location and experience, and follow-up univariate analyses suggested the increase in mood scores on Tension and decrease in scores on Calmness, Happiness, and Vigor between playing away and at home were significantly greater for Less experienced soccer players than Experienced players. Implications of these findings for the applied practitioner are discussed.     

Hypermnesia and total retrieval time

Recall performance sometimes improves over repeated recall attempts, a phenomenon dubbed hypermnesia. A critical theoretical issue is whether hypermnesia is due to repeated testing per se or increased retrieval time. The present experiments investigated by contrasting five testing conditions. All participants were presented with the same study list followed by either two shorter recall tests or a single longer test. In the multiple test conditions, the tests were either separated by a (filled) 7-minute interval (the multiple-split condition), or presented consecutively, with no break (the multiple-immediate condition). In the single test conditions, the test either began at the start of the recall session, after a (filled) 7-minute delay, or with a 7-minute interruption inserted in the middle. The multiple-split condition produced more reminiscence and hypermnesia than the multiple-immediate condition. More importantly, the multiple-split condition produced greater cumulative recall than any of the other conditions (which did not differ among themselves). That is, single and repeated recall tests of equal total duration are not functionally equivalent.     

The analysis of classroom talk: Methods and methodologies

This article describes methods for analysing classroom talk, comparing their strengths and weaknesses. Both quantitative and qualitative methods are described and assessed for their strengths and weaknesses, with a discussion of the mixed use of such methods. It is acknowledged that particular methods are often embedded in particular methodologies, which are based on specific theories of social action, research paradigms, and disciplines; and so a comparison is made of two contemporary methodologies, linguistic ethnography, and sociocultural research. The article concludes with some comments on the current state of development of this field of research and on ways that it might usefully progress.     

Positive and negative remember judgments and ROCs in the plurals paradigm: Evidence for alternative decision strategies

Using old-new ratings and remember-know judgments we explored the plurals paradigm, in which studied words must be distinguished from plurality-changed lures. The paradigm allowed us to investigate negative remembering—that is, the remembering of a plural-altered study item; capacity for this judgment was found to be poorer than or equivalent to the conventional positive remembering. A response-bias manipulation affected positive but not negative remembering. The ratings were used to construct ROC curves and test the prediction of the most common dual-process theory of recognition memory (Yonelinas, 2001) that the amount of recollection can be independently estimated from ROC curves and from remember judgments. By fitting the individual data with pure signal detection theory (SDT) models and dual-process models that combined SDT and high-threshold components (HTSDT), we identified two types of subjects. For those who were better described by HTSDT, the predicted convergence of remember-know and ROC measures was observed. For those who were better described by SDT, the ROC intercept could not predict the remember rate. The data are consistent with the idea that all subjects rely on the same representation but base their decisions on different partitions of a decision space.     

Effects of survival processing and retention interval on true and false recognition in the DRM and category repetition paradigms

ABSTRACT

Two experiments examined the effects of survival processing and delay on true and related false recognition. Experiment 1 used the Deese-Roediger-McDermott paradigm and found survival processing to increase true and related false recognition. Extending the delay from 5-mins to 1-day reduced true, but not false memory. Measures of the characteristics of true and false memories showed survival processing increased “remember” and “know” responses for related false memory, “know” responses for true memory and gist processing. Experiment 2 made use of the category repetition procedure and found a broadly similar pattern of results for true memory. However, related false memory was decreased by survival processing. Except for one result, no interactions were found between encoding task and delay. Overall, survival processing produced similar or different effects on true/false memory depending on the nature of the list. The mechanisms that might underpin these are evaluated and considered in relation to future work.     

On the importance of models in interpreting remember-know experiments: Comments on Gardiner et al.'s (2002) meta-analysis

From a meta-analysis of recognition experiments using the remember-know-guess paradigm, Gardiner, Ramponi, and Richardson-Klavehn (2002) reported two findings that they viewed as evidence against the one-dimensional model for that paradigm: (1) Memory strength increased when know responses were added to remember responses, decreasing when guess responses were also included. (2) The accuracy of guess responses was correlated with the location of the old-new criterion in the one-dimensional model for the paradigm, implying that guesses were influenced by decision processes. We question both findings. The first result is contradicted by a signal-detection (SDT) analysis, which shows that both know and guess responses reduced estimated memory strength. The discrepancy results from the properties of A′, the measure of accuracy used by Gardiner et al., which we argue is flawed. The second result follows directly from the one-dimensional model, in which accuracy and response criteria are fixed. The authors' reasons for rejecting the one-dimensional model are thus not persuasive, but it can nonetheless be rejected because ROC curves implied by the data are inconsistent with ROCs derived from ratings experiments. A two-dimensional SDT model (Rotello, Macmillan, & Reeder, 2004) accounts for both sets of data. The analysis illustrates the importance of models in interpreting remember-know data.