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81.
82.
The Francis Scale of Attitude toward Alcohol was completed by 324 adolescents (M= 17.1 yr., SD=3.6) in Northern Ireland to examine reliability of the measure among this age group. These data support its internal consistency (.89) and suggest that the Francis Scale of Attitude toward Alcohol is psychometrically appropriate for use among this age group. 相似文献
83.
84.
Drugs modulating gamma-aminobutyric acid (GABA) transmission via the benzodiazepine (BZ) site on the gamma-aminobutyric acid type A (GABAA) receptor have been in widespread use for more than 40 years to treat anxiety, epilepsy, and sleep disorders. These drugs have been shown to be safe, well tolerated, and effective although the mechanism by they produce a myriad of pharmacologic effects remains elusive. In recent years it has been discovered that, although the GABAA receptor is widely distributed in the brain, the substructure and composition of the receptor differs from between brain regions. Termed "GABAA receptor subtypes" their discovery leads to speculation that different subtypes may mediate specific effects of BZs such as anxiety or sedation. The phenotypic analysis of transgenic knock-in and knock-out mice in which particular GABAA receptors were rendered insensitive to the effects of BZ while others were unaffected confirmed this speculation. Subsequently, subtype-specific GABAA ligands were developed that, for example, retained the anxiolytic effects of BZs but were devoid of their sedative effects. Therefore, it may be possible to develop effective anxiolytic compounds that have a much reduced side-effect profile compared with existing drugs. 相似文献
85.
Gurry F 《Science and engineering ethics》2005,11(1):13-20
Intellectual property has historically been a self-contained policy at the international level. With the introduction of the
TRIPs Agreement in 1994 and developments since the conclusion of the TRIPs Agreement, the relationship between intellectual
property policy and other areas of public policy has become much more complex and interactive. This shift reflects the centrality
of intellectual property in the knowledge economy, the rapid development of enabling technologies, notably the Internet and
biotechnology, and the advent of the networked society. The consequences of this shift are manifold and herald the increased
sophistication and complexity that may be expected of intellectual property regimes in the knowledge economy.
An earlier version of this paper was presented at an international conference, “The Ethics of Intellectual Property Rights
and Patents,” held in Warsaw, Poland on 23–24 April, 2004. 相似文献
86.
Meza FR 《The journal of pastoral care & counseling : JPCC》2005,59(3):185-199
The author examines the history of theological method based on the term locus theologicus, the refinement of this method by Liberation Theologians and U. S. Hispanic/Latino/a Theologians, and describes one experience of using contextual theology to develop curriculum for Second-Year Clinical Pastoral Education (CPE) Residents. 相似文献
87.
The current research considered the effects of gaze direction on a fundamental aspect of social cogition: person memory. It was anticipated that a person's direction of gaze (i.e., direct or averted) would impact his or her subsequent memorability, such that recognition would be enhanced for targets previously displaying direct gaze. In Experiment 1, participants were presented with faces displaying either direct or averted gaze in a person-classification (i.e., conceptual) task. Then, in a surprise memory test, they were required to report whether a presented face had been seen before. As expected, a recognition advantage was observed for targets displaying direct gaze during the initial classification task. This finding was replicated and extended in a second experiment in which participants initially reported the spatial location (i.e., perceptual task) of each face. We consider the implications of these findings for basic aspects of social-cognitive functioning and person perception. 相似文献
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89.
The present study investigated the relative extent to which patients' adjustment to chronic low back pain (CLBP) was influenced by their fear-avoidance beliefs, their tendency to catastrophize, and their appraisals of control. Eighty-three CLBP patients completed a series of self-report measures before participating in a physical therapist-led intervention. Hierarchical multiple regression analyses revealed that patients' perceptions of their ability to decrease pain explained a small, but statistically significant, proportion of the variance in pain intensity. In addition, patients' levels of catastrophizing, as well as their fear-avoidance beliefs about both work and physical activity, were independently associated with levels of disability. Interestingly, however, when exploring the relative predictive utility of these three psychological factors, it became evident that fear-avoidance beliefs about physical activity (FABs-PA) were the only significant predictor of patients' disability. Specifically, those patients who exhibited higher levels of FABs-PA tended to report greater levels of disability, even after adjusting for age, sex and pain intensity. 相似文献
90.
The authors examined participants' estimates of own and parental psychometric intelligence (IQ) and emotional intelligence (EI). The authors asked 224 participants (82 men, 138 women, 4 people who did not report their gender) to estimate their own and their parents' IQ and EI scores on a normal distribution ranging from 55 to 145 points. The authors hypothesized that men would give higher IQ but lower EI self-estimates than women and that participants, regardless of gender, would rate their fathers as higher on IQ but lower on EI than their mothers. The results confirmed the hypotheses, supporting the view that people perceive psychometric intelligence as a primarily masculine attribute in contrast with emotional intelligence, which they perceive as a primarily feminine attribute. The results also showed that the intensity of the stereotypical perception of EI as a feminine attribute diminished when the authors asked participants to estimate their scores on a range of specific EI facets instead of providing a direct overall self-estimate. 相似文献