MIGHT KANTIAN CONTRACTUALISM BE THE SUPREME PRINCIPLE OF MORALITY?

According to Parfit, the best version of Kantian ethics takes as its central principle Kantian Contractualism: the thesis that everyone ought to follow the principles whose universal acceptance everyone could rationally will. This paper examines that thesis, identifies a class of annoying counterexamples, and suggests that when Kantian Contractualism is modified in response to these examples, the resulting principle is too complex and ad hoc to serve as the 'supreme principle of morality'.     

The Effectiveness of Family History Questionnaires in Cancer Genetic Counseling

The number of individuals receiving genetic counseling for hereditary breast and ovarian cancer syndrome has steadily risen. To triage patients for genetic counseling and to help reduce the amount of time needed by a genetic counselor in direct patient contact, many clinics have implemented the use of family history questionnaires. Although such questionnaires are widely used, scant literature exists evaluating their effectiveness. This article explores the extent to which family history questionnaires are being used in Ontario and addresses the utility of such questionnaires in one familial cancer clinic. By comparing the pedigrees created from questionnaires to those updated during genetic counseling, the accuracy and effectiveness of the questionnaires was explored. Of 121 families recruited into the study, 12% acquired changes to their pedigree that led to a revised probability estimate for having a BRCA1 or BRCA2 mutation and 5% acquired changes that altered their eligibility for genetic testing. No statistically significant difference existed between the eligibility for genetic testing prior to and post counseling. This suggests that family history questionnaires can be effective at obtaining a family history and accurately assessing eligibility for genetic testing. Based on the variables that were significantly associated with a change in probability estimate, we further present recommendations for improving the clarity of such questionnaires and therefore the ease of use by patients.     

Bayesian journey-to-crime modelling of juvenile and adult offenders by gender in Manchester

This study tested the Bayesian journey-to-crime (JTC) model by gender and age for serial offenders from Manchester, England. The data were 4056 crimes committed by 171 serial offenders between 2003 and 2006. The data were subdivided by gender and age group to examine whether accuracy and precision varied by these subgroups. In general, the centre of minimum distance was found to be the most accurate measure, but the Bayesian risk and product measures were found to be the most precise measurements. The traditional ‘distance decay’ type of JTC function did not produce estimates that are as accurate nor as precise as the Bayesian approach. Tests were conducted on whether specific gender and age group JTC functions and origin–destination matrices improved predictability. With the exception of juvenile male offenders, the general functions were more accurate and precise. In terms of building an accurate and precise geographical profiling methodology, the results point to the need to include information on the likely predisposition of neighbourhoods to produce offenders as well as information on the crime opportunities available to offenders. Copyright © 2009 John Wiley & Sons, Ltd.     

Jaynes' chimeric faces: Another look into the mirror

In The Origin of Consciousness in the Breakdown of the Bicameral Mind, Jaynes (1976) presented a technique—involving the selection of the happier of two line-drawing chimeric faces—that is theorized to measure hemispheric laterality. Certain imperfections in the published stimuli have led some critics to question the task's validity, while others maintain that even the flawed stimuli are measuring some aspect of laterality. In this study, further data are presented to show that this task, despite its inherent biases, is still sensitive to differences in perception between left-handers and right-handers. The implications of this sensitivity are discussed.     

Slowed lexical access in nonfluent aphasia: a case study.

A list priming paradigm (LPP) was used to examine the hypothesis that nonfluent aphasics are literally slowed down in automatic access to lexical information. In this paradigm, words are presented visually, and the subject's task is to make a lexical decision on each word as quickly as possible after its presentation. As soon as a lexical decision is made on one word, that word is removed and, after a predetermined interword interval, the next word is presented. In this way, a continuous "list" effect is obtained. Prior studies with both college-age and elderly subjects using the LPP have shown that, independently of age, on the LPP, priming obtains at interword delays of 500 to 800 msec, but not at either shorter or longer interword delays. In the study reported here, the LPP was used to examine delays at which priming obtained for LD, a nonfluent aphasic with a lesion primarily in the left frontal region. Examining interword delays ranging from 500 to 1800 msec, the subject showed priming only at a delay of 1500 msec, a considerably longer delay than that at which neurologically intact subjects have shown priming. Based on these results, it is argued that while automatic access is retained, that access is much slower in a nonfluent aphasic than in neurologically intact elderly subjects. These results are discussed in terms of how slowed lexical access might impact on discourse comprehension.