Depressive symptoms during pregnancy: impact on neuroendocrine and neonatal outcomes

Objective

To explore the interplay of maternal depressive symptoms on the infant limbic-hypothalamic-pituitary axis (LHPA) and neurological development.

Design

Pregnant women were monitored for depressive symptoms using the Beck Depression Inventory (BDI) at 28, 32, and 37 weeks of gestation and at delivery. A mixture growth curve analysis divided the women into three risk groups: low/stable, intermediate, and high/increasing depression based on BDI scores. The infant neuroendocrine system was examined using cord blood for adrenocorticotrophic hormone (ACTH) and cortisol measurements. Two-week-old infants were examined using Neonatal Intensive Care Unit Neurobehavioral Scale (NNNS).

Results

Infants born to women of the high/increasing depression group had significant ACTH elevation at birth. On NNNS examination, these infants were more hypotonic and habituated to auditory and visual stimuli.

Conclusion

When compared to non-depressed women, maternal depressive symptoms, even in the absence of major depressive disorder, appeared to facilitate a different developmental pathway for the infant LHPA and early neurological development.     

Prayer to the Saints or the Virgin And Health Among Older Mexican Americans

The purpose of this study was to evaluate a conceptual model that assesses whether praying to the saints or the Virgin is associated with the health of older Mexican Americans. A survey was conducted of 1,005 older Mexican Americans (Mean age = 73.9 years; SD = 6.6 years). Data from 795 of the Catholic respondents are presented in this study. The findings support the following relationships that are embedded in the conceptual model: (1) older Mexican Americans who attend church more often are more likely to believe in the efficacy of prayer to the saints or the Virgin; (2) stronger beliefs in the efficacy of intercessory prayer are associated with more frequent prayer to the saints or the Virgin; (3) frequent prayer is to the saints or the Virgin is associated with greater God-mediated control beliefs; (4) stronger God-mediated control beliefs are associated with greater optimism; and (5) greater optimism is associated with better self-rated health.     

How do I remember that I know you know that I know?

Communication is aided greatly when speakers and listeners take advantage of mutually shared knowledge (i.e., common ground). How such information is represented in memory is not well known. Using a neuropsychological-psycholinguistic approach to real-time language understanding, we investigated the ability to form and use common ground during conversation in memory-impaired participants with hippocampal amnesia. Analyses of amnesics' eye fixations as they interpreted their partner's utterances about a set of objects demonstrated successful use of common ground when the amnesics had immediate access to common-ground information, but dramatic failures when they did not. These findings indicate a clear role for declarative memory in maintenance of common-ground representations. Even when amnesics were successful, however, the eye movement record revealed subtle deficits in resolving potential ambiguity among competing intended referents; this finding suggests that declarative memory may be critical to more basic aspects of the on-line resolution of linguistic ambiguity.     

The Perceived Prayers of Others,Stress, and Change in Depressive Symptoms Over Time

The purpose of this study was to see if believing that others are praying for them reduces the noxious effect of living in a rundown neighborhood on change in depressive symptoms among older people. Findings from a longitudinal nationwide survey of older adults reveal that the deleterious effect of living in a dilapidated neighborhood on depressive symptoms is significantly reduced for older individuals who believe others often pray for them. Further analyses suggest that the stress-buffering properties of beliefs about being prayed for by others remain virtually unchanged after emotional support from family members and close friends is taken into account. The findings have potentially important implications for studying church-based prayer groups as well as assessing the ways in which individuals might support each other during difficult times.     

Reported Contact with the Dead, Religious Involvement, and Death Anxiety in Late Life

The purpose of this study is to examine the relationship between contact with the dead and death anxiety. The data come from an ongoing nationwide survey of older adults. A conceptual model is developed that contains the following theoretical linkages: (1) making contact with the dead instills a deeper appreciation of the connection that exists among all people; (2) this fundamental sense of connectedness with others fosters a deeper sense of religious meaning in life; and (3) individuals with a deeper sense of religious meaning in life are less likely to experience feelings of death anxiety than people who have not been able to find meaning in life through religion. The findings from this study provide support for each of these relationships. The theoretical implications of these hypotheses are discussed.     

Seven-month-old infants chunk items in memory

Although working memory has a highly constrained capacity limit of three or four items, both adults and toddlers can increase the total amount of stored information by "chunking" object representations in memory. To examine the developmental origins of chunking, we used a violation-of-expectation procedure to ask whether 7-month-old infants, whose working memory capacity is still maturing, also can chunk items in memory. In Experiment 1, we found that in the absence of chunking cues, infants failed to remember three identical hidden objects. In Experiments 2 and 3, we found that infants successfully remembered three hidden objects when provided with overlapping spatial and featural chunking cues. In Experiment 4, we found that infants did not chunk when provided with either spatial or featural chunking cues alone. Finally, in Experiment 5, we found that infants also failed to chunk when spatial and featural cues specified different chunks (i.e., were pitted against each other). Taken together, these results suggest that chunking is available before working memory capacity has matured but still may undergo important development over the first year of life.