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941.
Solution-focused counsellors use “scaling questions” to construct understandings of clients’ concerns and solutions to them. We examine how these questions are asked and answered, offering evidence of what is constructed from within counselling discourse. Also, clients and counsellors offer their retrospective accounts of their participation in question and answer sequences in their dialogues. We conclude by speaking to the implications we see from this research as it relates to collaborative and resourceful dialogue between counsellors and clients.  相似文献   
942.
ABSTRACT— Gene-environment interactions involving exogenous environmental factors are known to shape behavior and personality development. Although gene-environment interactions involving endogenous environmental factors are hypothesized to play an equally important role, this conceptual approach has not been empirically applied in the study of early-developing temperament in humans. Here we report evidence for a gene- endo environment (i.e., resting frontal brain electroencephalogram, EEG, asymmetry) interaction in predicting child temperament. The dopamine D4 receptor (DRD4) gene (long allele vs. short allele) moderated the relation between resting frontal EEG asymmetry (left vs. right) at 9 months and temperament at 48 months. Children who exhibited left frontal EEG asymmetry at 9 months and who possessed the DRD4 long allele were significantly more soothable at 48 months than other children. Among children with right frontal EEG asymmetry at 9 months, those with the DRD4 long allele had significantly more difficulties focusing and sustaining attention at 48 months than those with the DRD4 short allele. Resting frontal EEG asymmetry did not influence temperament in the absence of the DRD4 long allele. We discuss how the interaction of genetic and endoenvironmental factors may confer risk and protection for different behavioral styles in children.  相似文献   
943.
ABSTRACT— Functional imaging data were acquired during performance of a reward-contingency task in a unique cohort of adolescents (ages 14–18 years) who were characterized since infancy on measures of temperamental behavioral inhibition. Neural activation was examined in striatal structures (nucleus accumbens, putamen, caudate) with a known role in facilitating response to salient reward-related cues. Adolescents with a history of behavioral inhibition, relative to noninhibited adolescents, showed increased activation in the nucleus accumbens when they believed their selection of an action would affect reward outcome. Neural responses did not differ between the two groups when participants made a prespecified response that they knew would result in reward or when they produced random motor responses that they knew would not be rewarded. These results link inhibited temperament and perturbed neural responses to reward-contingency cues.  相似文献   
944.
Since genetic information has implications for family members, some choices about genetic risk may be influenced by perceptions of responsibility to relatives. Drawing upon 25 semi-structured interviews with test recipients in Canada, this study explored decisions about inherited breast-ovarian and colon cancer. Qualitative data analysis revealed the pervasive significance of genetic responsibility in test decisions. We highlight three dimensions of genetic responsibility: 1) to know about the self for self; 2) to know about the self for others; 3) to know about the self to oblige others to know. It is argued that these dimensions of genetic responsibility have implications for test decisions, family relationships and other family members’ desire to know (or not know) and to act (or not act) with respect to their own genetic risk. In particular, genetic responsibility may play out as a framing of a relative’s moral obligation to know their risk that could obviate any interest they might have in not knowing. We conclude that perceptions of responsibility to—and of−other family members be thoroughly explored in genetic counseling sessions.  相似文献   
945.
This study examined whether adolescent females with attention-deficit/hyperactivity disorder (ADHD) are differentially responsive than their male counterparts to extended-release stimulant medications. This investigation may bear special importance for an adolescent (as opposed to child) population, because hormonal and metabolism differences between sexes are most likely to emerge at this time. Male (n = 19) and female (n = 16) adolescents, ages 16–19 with ADHD, participated in a randomized, double-blind crossover study evaluating the effectiveness of osmotic-release methylphenidate, extended release amphetamine salts, placebo, and routine limited medication regimen. Medication efficacy was evaluated using ADHD symptom ratings from adolescent self-report and parent report, along with objective measures of inattention and hyperactivity/impulsivity during driving performance and neuropsychological tasks. Males and females were largely equivalent in impairment, and medication was similarly effective in reducing symptoms. No interactions were found between sex and medication on any measure of effectiveness or side effects. This finding suggests that the efficacy and tolerability of extended-release stimulant medications is equivalent for male and female adolescents with ADHD.  相似文献   
946.
A cornerstone of contemporary research in numerical cognition is the surprising link found between numbers and space. In particular, people react faster and more accurately to small numbers with a left-hand key and to large numbers with a right-hand key. Because this contingency is found in a variety of tasks, it has been taken to support the automatic activation of magnitude as well as the notion of a mental number line arranged from left to right. The present study challenges the presence of a link between left-right location, on the one hand, and small-large number, on the other hand. We show that a link exists between space and relative magnitude, a relationship that might or might not be unique to numbers.  相似文献   
947.
Previously, we demonstrated that mice in which the gene for the L-type voltage-gated calcium channel CaV1.3 is deleted (CaV1.3 knockout mice) exhibit an impaired ability to consolidate contextually-conditioned fear. Given that this form of Pavlovian fear conditioning is critically dependent on the basolateral complex of the amygdala (BLA), we were interested in the mechanisms by which CaV1.3 contributes to BLA neurophysiology. In the present study, we used in vitro amygdala slices prepared from CaV1.3 knockout mice and wild-type littermates to explore the role of CaV1.3 in long-term potentiation (LTP) and intrinsic neuronal excitability in the BLA. We found that LTP in the lateral nucleus (LA) of the BLA, induced by high-frequency stimulation of the external capsule, was significantly reduced in CaV1.3 knockout mice. Additionally, we found that BLA principal neurons from CaV1.3 knockout mice were hyperexcitable, exhibiting significant increases in firing rates and decreased interspike intervals in response to prolonged somatic depolarization. This aberrant increase in neuronal excitability appears to be at least in part due to a concomitant reduction in the slow component of the post-burst afterhyperpolarization. Together, these results demonstrate altered neuronal function in the BLA of CaV1.3 knockout mice which may account for the impaired ability of these mice to consolidate contextually-conditioned fear.  相似文献   
948.
Many clients who undergo methadone maintenance (MM) treatment for heroin and other opiate dependence prefer abstinence from methadone. Attempts at methadone detoxification are often unsuccessful, however, due to distressing physical as well as psychological symptoms. Outcomes from an MM client who voluntarily participated in an Acceptance and Commitment Therapy (ACT)–based methadone detoxification program are presented. The program consisted of a 1-month stabilization and 5-month gradual methadone dose reduction period, combined with weekly individual ACT sessions. Urine samples were collected twice weekly to assess for use of illicit drugs. The participant successfully completed the program and had favorable drug use outcomes during the course of treatment, and at the 1-month and 1-year follow-ups. Innovative behavior therapies, such as ACT, that focus on acceptance of the inevitable distress associated with opiate withdrawal may improve methadone detoxification outcomes.  相似文献   
949.
Background This study examines the effects of integrated and segregated schooling on Northern Irish children's self‐reported contact and friendship with members of the other denominational group in school and community settings. Aim To assess the effects of cross group friendships and cross group contacts in school and outside school on children's political attitudes. Sample A cross‐sectional design was employed with 1732 children being assessed at three age levels 11,12 & 14 years in eight‐matched integrated, maintained (Catholic) and controlled (Protestant) schools. Method Lisrel modelling was used to investigate the interrelationships among cross group friendship quality, cross group contacts in school and outside school and children's political attitudes. Results Intergroup contact within and outside school was reported frequently in integrated schools but only occasionally in segregated schools. Modelling revealed that cross group contacts in school and outside school were both associated with less extreme political attitudes. Friendship quality with cross group members had no significant effects on political attitudes. Conclusions The results provide support for educating Protestants and Catholics together as a means of moderating attitudes and creating cross‐community friendships in a divided society.  相似文献   
950.
In 2007 Protestants in China celebrated the 200th anniversary of their journey of faith. The continuing concern of Chinese Christian theological educators is to rejuvenate Christianity in China by critically adapting to the contemporary socialist order and the best religio‐cultural tradition of Chinese society. Chinese Christians have been challenged by the socialist order of society particularly because of the political and social changes that have taken place in China since the establishment of the People's Republic of China in 1949 and the changes brought about within Chinese society. With the end of the Cultural Revolution (1966–1976) and the change of political atmosphere in 1978 there has been once again an opening for public Christian activities within the confines of certain state regulations. This change has provided scope for pursuing the reconstruction in China of Christianity initiated in the 1950s under the Three Self Patriotic Movement (TSPM). Besides the revival of TSPM, the Chinese leaders have set up another instrument, the China Christian Council (CCC) especially to cater to the surging pastoral and congregational needs. This article briefly surveys the development of the vision of reconstructing Christianity through “theological reconstruction” and the need for ecumenical accompaniment.  相似文献   
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